| G protein-coupled receptors: novel targets for drug discovery in cancer R Lappano, M Maggiolini Nature reviews Drug discovery 10 (1), 47-60, 2011 | 779 | 2011 |
| G protein–coupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17β-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells L Albanito, A Madeo, R Lappano, A Vivacqua, V Rago, A Carpino, ... Cancer research 67 (4), 1859-1866, 2007 | 530 | 2007 |
| Estrogenic GPR30 signalling induces proliferation and migration of breast cancer cells through CTGF DP Pandey, R Lappano, L Albanito, A Madeo, M Maggiolini, D Picard The EMBO journal 28 (5), 523-532, 2009 | 399 | 2009 |
| Bisphenol A induces gene expression changes and proliferative effects through GPER in breast cancer cells and cancer-associated fibroblasts M Pupo, A Pisano, R Lappano, MF Santolla, EM De Francesco, ... Environmental health perspectives 120 (8), 1177-1182, 2012 | 329 | 2012 |
| HIF-1α/GPER signaling mediates the expression of VEGF induced by hypoxia in breast cancer associated fibroblasts (CAFs) EM De Francesco, R Lappano, MF Santolla, S Marsico, A Caruso, ... Breast Cancer Research 15, 1-18, 2013 | 268 | 2013 |
| A review on the antimicrobial activity of Schiff bases: Data collection and recent studies J Ceramella, D Iacopetta, A Catalano, F Cirillo, R Lappano, MS Sinicropi Antibiotics 11 (2), 191, 2022 | 252 | 2022 |
| The novel estrogen receptor, G protein-coupled receptor 30, mediates the proliferative effects induced by 17β-estradiol on mouse spermatogonial GC-1 cell line R Sirianni, A Chimento, C Ruggiero, A De Luca, R Lappano, S Andò, ... Endocrinology 149 (10), 5043-5051, 2008 | 198 | 2008 |
| Epidermal growth factor induces G protein-coupled receptor 30 expression in estrogen receptor-negative breast cancer cells L Albanito, D Sisci, S Aquila, E Brunelli, A Vivacqua, A Madeo, R Lappano, ... Endocrinology 149 (8), 3799-3808, 2008 | 184 | 2008 |
| G protein-coupled receptor 30 expression is up-regulated by EGF and TGFα in estrogen receptor α-positive cancer cells A Vivacqua, R Lappano, P De Marco, D Sisci, S Aquila, F De Amicis, ... Molecular Endocrinology 23 (11), 1815-1826, 2009 | 174 | 2009 |
| Copper activates HIF-1α/GPER/VEGF signalling in cancer cells DC Rigiracciolo, A Scarpelli, R Lappano, A Pisano, MF Santolla, ... Oncotarget 6 (33), 34158, 2015 | 161 | 2015 |
| GPER mediates activation of HIF1α/VEGF signaling by estrogens EM De Francesco, M Pellegrino, MF Santolla, R Lappano, E Ricchio, ... Cancer research 74 (15), 4053-4064, 2014 | 158 | 2014 |
| The lauric acid-activated signaling prompts apoptosis in cancer cells R Lappano, A Sebastiani, F Cirillo, DC Rigiracciolo, GR Galli, R Curcio, ... Cell death discovery 3 (1), 1-9, 2017 | 157 | 2017 |
| Estriol acts as a GPR30 antagonist in estrogen receptor-negative breast cancer cells R Lappano, C Rosano, P De Marco, EM De Francesco, V Pezzi, ... Molecular and cellular endocrinology 320 (1-2), 162-170, 2010 | 145 | 2010 |
| Retracted: G-protein–coupled receptor 30 and estrogen receptor-α are involved in the proliferative effects induced by atrazine in ovarian cancer cells L Albanito, R Lappano, A Madeo, A Chimento, ER Prossnitz, AR Cappello, ... Environmental Health Perspectives 116 (12), 1648-1655, 2008 | 145 | 2008 |
| The cholesterol metabolite 25-hydroxycholesterol activates estrogen receptor α-mediated signaling in cancer cells and in cardiomyocytes R Lappano, AG Recchia, EM De Francesco, T Angelone, MC Cerra, ... PloS one 6 (1), e16631, 2011 | 126 | 2011 |
| GPCRs and cancer R Lappano, M Maggiolini Acta pharmacologica sinica 33 (3), 351-362, 2012 | 125 | 2012 |
| GPER function in breast cancer: an overview R Lappano, A Pisano, M Maggiolini Frontiers in endocrinology 5, 66, 2014 | 124 | 2014 |
| Insulin-like growth factor-I regulates GPER expression and function in cancer cells P De Marco, V Bartella, A Vivacqua, R Lappano, MF Santolla, ... Oncogene 32 (6), 678-688, 2013 | 121 | 2013 |
| MIBE acts as antagonist ligand of both estrogen receptor α and GPER in breast cancer cells R Lappano, MF Santolla, M Pupo, MS Sinicropi, A Caruso, C Rosano, ... Breast Cancer Research 14, 1-13, 2012 | 119 | 2012 |
| G protein-coupled estrogen receptor mediates the up-regulation of fatty acid synthase induced by 17β-estradiol in cancer cells and cancer-associated fibroblasts MF Santolla, R Lappano, P De Marco, M Pupo, A Vivacqua, D Sisci, ... Journal of Biological Chemistry 287 (52), 43234-43245, 2012 | 111 | 2012 |
