Glucose metabolism links astroglial mitochondria to cannabinoid effects D Jimenez-Blasco, A Busquets-Garcia, E Hebert-Chatelain, R Serrat, ... Nature 583 (7817), 603-608, 2020 | 222 | 2020 |
Astrocyte NMDA receptors' activity sustains neuronal survival through a Cdk5–Nrf2 pathway D Jimenez-Blasco, P Santofimia-Castaño, A Gonzalez, A Almeida, ... Cell Death & Differentiation 22 (11), 1877-1889, 2015 | 190 | 2015 |
Astrocytic mitochondrial ROS modulate brain metabolism and mouse behaviour C Vicente-Gutierrez, N Bonora, V Bobo-Jimenez, D Jimenez-Blasco, ... Nature metabolism 1 (2), 201-211, 2019 | 164 | 2019 |
Fatty acid oxidation organizes mitochondrial supercomplexes to sustain astrocytic ROS and cognition B Morant-Ferrando, D Jimenez-Blasco, P Alonso-Batan, J Agulla, ... Nature metabolism 5 (8), 1290-1302, 2023 | 80 | 2023 |
Melatonin induces the expression of Nrf2-regulated antioxidant enzymes via PKC and Ca2+ influx activation in mouse pancreatic acinar cells P Santofimia-Castaño, DC Ruy, L Garcia-Sanchez, D Jimenez-Blasco, ... Free Radical Biology and Medicine 87, 226-236, 2015 | 69 | 2015 |
DJ1 represses glycolysis and cell proliferation by transcriptionally upregulating pink1 R Requejo-Aguilar, I Lopez-Fabuel, D Jimenez-Blasco, E Fernandez, ... The Biochemical Journal 467 (2), 303, 2015 | 67 | 2015 |
Targeting PFKFB3 alleviates cerebral ischemia-reperfusion injury in mice O Burmistrova, A Olias-Arjona, R Lapresa, D Jimenez-Blasco, ... Scientific reports 9 (1), 11670, 2019 | 61 | 2019 |
Regulation of Bcl-xL–ATP synthase interaction by mitochondrial cyclin B1–cyclin-dependent kinase-1 determines neuronal survival MVP de Tudela, M Delgado-Esteban, C Maestre, V Bobo-Jiménez, ... Journal of Neuroscience 35 (25), 9287-9301, 2015 | 61 | 2015 |
Cell identity and nucleo-mitochondrial genetic context modulate OXPHOS performance and determine somatic heteroplasmy dynamics AV Lechuga-Vieco, A Latorre-Pellicer, IG Johnston, G Prota, U Gileadi, ... Science advances 6 (31), eaba5345, 2020 | 46 | 2020 |
γ-Linolenic acid in maternal milk drives cardiac metabolic maturation A Paredes, R Justo-Méndez, D Jiménez-Blasco, V Núñez, I Calero, ... Nature 618 (7964), 365-373, 2023 | 45 | 2023 |
Cross-talk between energy and redox metabolism in astrocyte-neuron functional cooperation A Almeida, D Jimenez-Blasco, JP Bolaños Essays in Biochemistry 67 (1), 17-26, 2023 | 43 | 2023 |
LRRK2 expression is deregulated in fibroblasts and neurons from Parkinson patients with mutations in PINK1 G Azkona, R López de Maturana, P Del Rio, A Sousa, N Vazquez, ... Molecular neurobiology 55 (1), 506-516, 2018 | 41 | 2018 |
Intertwined ROS and metabolic signaling at the neuron-astrocyte interface C Vicente-Gutiérrez, D Jiménez-Blasco, R Quintana-Cabrera Neurochemical Research 46 (1), 23-33, 2021 | 29 | 2021 |
Aberrant upregulation of the glycolytic enzyme PFKFB3 in CLN7 neuronal ceroid lipofuscinosis I Lopez-Fabuel, M Garcia-Macia, C Buondelmonte, O Burmistrova, ... Nature Communications 13 (1), 536, 2022 | 24 | 2022 |
Neuronal p38α mediates age‐associated neural stem cell exhaustion and cognitive decline L Moreno‐Cugnon, M Revuelta, O Arrizabalaga, S Colie, ... Aging Cell 18 (6), e13044, 2019 | 23 | 2019 |
Abrogating mitochondrial ROS in neurons or astrocytes reveals cell-specific impact on mouse behaviour C Vicente-Gutierrez, N Bonora, D Jimenez-Blasco, I Lopez-Fabuel, ... Redox Biology 41, 101917, 2021 | 15 | 2021 |
Weak neuronal glycolysis sustains cognition and organismal fitness D Jimenez-Blasco, J Agulla, R Lapresa, M Garcia-Macia, V Bobo-Jimenez, ... Nature Metabolism, 1-15, 2024 | 13 | 2024 |
p38γ and p38δ regulate postnatal cardiac metabolism through glycogen synthase 1 AM Santamans, V Montalvo-Romeral, A Mora, JA Lopez, ... PLoS biology 19 (11), e3001447, 2021 | 12 | 2021 |
Brightness and shadows of mitochondrial ROS in the brain D Jimenez-Blasco, A Almeida, JP Bolaños Neurobiology of Disease 184, 106199, 2023 | 8 | 2023 |
Potent, selective and reversible hMAO-B inhibition by benzalphthalides: Synthesis, enzymatic and cellular evaluations and virtual docking and predictive studies E Del Olmo, B Barboza, M Delgado-Esteban, N Escala, D Jimenez-Blasco, ... Bioorganic Chemistry 146, 107255, 2024 | 2 | 2024 |