| Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation H Huang, H Weng, W Sun, X Qin, H Shi, H Wu, BS Zhao, A Mesquita, ... Nature cell biology 20 (3), 285-295, 2018 | 2340 | 2018 |
| FTO plays an oncogenic role in acute myeloid leukemia as a N6-methyladenosine RNA demethylase Z Li, H Weng, R Su, X Weng, Z Zuo, C Li, H Huang, S Nachtergaele, ... Cancer cell 31 (1), 127-141, 2017 | 1380 | 2017 |
| R-2HG exhibits anti-tumor activity by targeting FTO/m6A/MYC/CEBPA signaling R Su, L Dong, C Li, S Nachtergaele, M Wunderlich, Y Qing, X Deng, ... Cell 172 (1), 90-105. e23, 2018 | 982 | 2018 |
| The dynamic N1-methyladenosine methylome in eukaryotic messenger RNA D Dominissini, S Nachtergaele, S Moshitch-Moshkovitz, E Peer, N Kol, ... Nature 530 (7591), 441-446, 2016 | 963 | 2016 |
| RNA m6A methylation regulates the ultraviolet-induced DNA damage response Y Xiang, B Laurent, CH Hsu, S Nachtergaele, Z Lu, W Sheng, C Xu, ... Nature 543 (7646), 573-576, 2017 | 848 | 2017 |
| Structural basis of Smoothened regulation by its extracellular domains EFX Byrne, R Sircar, PS Miller, G Hedger, G Luchetti, S Nachtergaele, ... Nature 535 (7613), 517-522, 2016 | 381 | 2016 |
| Oxysterols are allosteric activators of the oncoprotein Smoothened S Nachtergaele, LK Mydock, K Krishnan, J Rammohan, PH Schlesinger, ... Nature chemical biology 8 (2), 211-220, 2012 | 330 | 2012 |
| Cholesterol activates the G-protein coupled receptor Smoothened to promote Hedgehog signaling G Luchetti, R Sircar, JH Kong, S Nachtergaele, A Sagner, EFX Byrne, ... Elife 5, e20304, 2016 | 248 | 2016 |
| The emerging biology of RNA post-transcriptional modifications S Nachtergaele, C He RNA biology 14 (2), 156-163, 2017 | 245 | 2017 |
| Chemical modifications in the life of an mRNA transcript S Nachtergaele, C He Annual review of genetics 52 (1), 349-372, 2018 | 200 | 2018 |
| Structure and function of the Smoothened extracellular domain in vertebrate Hedgehog signaling S Nachtergaele, DM Whalen, LK Mydock, Z Zhao, T Malinauskas, ... Elife 2, e01340, 2013 | 192 | 2013 |
| Evolution of a reverse transcriptase to map N1-methyladenosine in human messenger RNA H Zhou, S Rauch, Q Dai, X Cui, Z Zhang, S Nachtergaele, C Sepich, C He, ... Nature methods 16 (12), 1281-1288, 2019 | 165 | 2019 |
| A novel osteogenic oxysterol compound for therapeutic development to promote bone growth: activation of hedgehog signaling and osteogenesis through smoothened binding SR Montgomery, T Nargizyan, V Meliton, S Nachtergaele, R Rohatgi, ... Journal of Bone and Mineral Research 29 (8), 1872-1885, 2014 | 80 | 2014 |
| mRNA regulation by RNA modifications WV Gilbert, S Nachtergaele Annual Review of Biochemistry 92 (1), 175-198, 2023 | 79 | 2023 |
| Functional role of Tet-mediated RNA hydroxymethylcytosine in mouse ES cells and during differentiation J Lan, N Rajan, M Bizet, A Penning, NK Singh, D Guallar, E Calonne, ... Nature communications 11 (1), 4956, 2020 | 72 | 2020 |
| Three-dimensional nanocrystal superlattices grown in nanoliter microfluidic plugs MI Bodnarchuk, L Li, A Fok, S Nachtergaele, RF Ismagilov, DV Talapin Journal of the American Chemical Society 133 (23), 8956-8960, 2011 | 67 | 2011 |
| Our views of dynamic N6-methyladenosine RNA methylation BS Zhao, S Nachtergaele, IA Roundtree, C He Rna 24 (3), 268-272, 2018 | 50 | 2018 |
| Functional divergence in the role of N-linked glycosylation in smoothened signaling S Marada, G Navarro, A Truong, DP Stewart, AM Arensdorf, ... PLoS genetics 11 (8), e1005473, 2015 | 47 | 2015 |
| The METTL5-TRMT112 N6-methyladenosine methyltransferase complex regulates mRNA translation via 18S rRNA methylation C Sepich-Poore, Z Zheng, E Schmitt, K Wen, ZS Zhang, XL Cui, Q Dai, ... Journal of Biological Chemistry 298 (3), 2022 | 45 | 2022 |
| Simple Host− Guest Chemistry To Modulate the Process of Concentration and Crystallization of Membrane Proteins by Detergent Capture in a Microfluidic Device L Li, S Nachtergaele, AM Seddon, V Tereshko, N Ponomarenko, ... Journal of the American Chemical Society 130 (43), 14324-14328, 2008 | 40 | 2008 |