| High-level semi-synthetic production of the potent antimalarial artemisinin CJ Paddon, PJ Westfall, DJ Pitera, K Benjamin, K Fisher, D McPhee, ... Nature 496 (7446), 528-532, 2013 | 2347 | 2013 |
| Production of amorphadiene in yeast, and its conversion to dihydroartemisinic acid, precursor to the antimalarial agent artemisinin PJ Westfall, DJ Pitera, JR Lenihan, D Eng, FX Woolard, R Regentin, ... Proceedings of the National Academy of Sciences 109 (3), E111-E118, 2012 | 848 | 2012 |
| Semi-synthetic artemisinin: a model for the use of synthetic biology in pharmaceutical development CJ Paddon, JD Keasling Nature reviews microbiology 12 (5), 355-367, 2014 | 824 | 2014 |
| Recombination-mediated PCR-directed plasmid construction in vivo in yeast O Kevin R, KT Vo, S Michaelis, C Paddon Nucleic acids research 25 (2), 451-452, 1997 | 687 | 1997 |
| Balancing a heterologous mevalonate pathway for improved isoprenoid production in Escherichia coli DJ Pitera, CJ Paddon, JD Newman, JD Keasling Metabolic engineering 9 (2), 193-207, 2007 | 553 | 2007 |
| Global Transcriptional Response of Bacillus subtilis to Heat Shock JD Helmann, MFW Wu, PA Kobel, FJ Gamo, M Wilson, MM Morshedi, ... Journal of Bacteriology 183 (24), 7318-7328, 2001 | 332 | 2001 |
| De novo sequencing, assembly and analysis of the genome of the laboratory strain Saccharomyces cerevisiae CEN.PK113-7D, a model for modern industrial … JF Nijkamp, M van den Broek, E Datema, S de Kok, L Bosman, MA Luttik, ... Microbial cell factories 11, 1-17, 2012 | 298 | 2012 |
| The Global Transcriptional Response of Bacillus subtilis to Peroxide Stress Is Coordinated by Three Transcription Factors JD Helmann, MFW Wu, A Gaballa, PA Kobel, MM Morshedi, P Fawcett, ... Journal of Bacteriology 185 (1), 243-253, 2003 | 289 | 2003 |
| Defining the Bacillus subtilis σW regulon: a comparative analysis of promoter consensus search, run-off transcription/macroarray analysis (ROMA), and transcriptional profiling … M Cao, PA Kobel, MM Morshedi, MFW Wu, C Paddon, JD Helmann Journal of molecular biology 316 (3), 443-457, 2002 | 235 | 2002 |
| Induction of multiple pleiotropic drug resistance genes in yeast engineered to produce an increased level of anti-malarial drug precursor, artemisinic acid DK Ro, M Ouellet, EM Paradise, H Burd, D Eng, CJ Paddon, JD Newman, ... BMC biotechnology 8, 1-14, 2008 | 231 | 2008 |
| Functional coupling of mammalian receptors to the yeast mating pathway using novel yeast/mammalian G protein α‐subunit chimeras AJ Brown, SL Dyos, MS Whiteway, JHM White, MAEA Watson, ... Yeast 16 (1), 11-22, 2000 | 229 | 2000 |
| Developing fermentative terpenoid production for commercial usage MD Leavell, DJ McPhee, CJ Paddon Current opinion in biotechnology 37, 114-119, 2016 | 130 | 2016 |
| Approaches and recent developments for the commercial production of semi-synthetic artemisinin SH Kung, S Lund, A Murarka, D McPhee, CJ Paddon Frontiers in plant science 9, 87, 2018 | 113 | 2018 |
| Expression of Bacillus amyloliquefaciens extracellular ribonuclease (barnase) in Escherichia coli following an inactivating mutation CJ Paddon, RW Hartley Gene 53 (1), 11-19, 1987 | 80 | 1987 |
| Developing commercial production of semi-synthetic artemisinin, and of β-Farnesene, an isoprenoid produced by fermentation of Brazilian sugar KR Benjamin, IR Silva, JP Cherubim, D McPhee, CJ Paddon Journal of the Brazilian Chemical Society 27 (8), 1339-1345, 2016 | 70 | 2016 |
| Cloning, sequencing and transcription of an inactivated copy of Bacillus amyloliquefaciens extracellular ribonuclease (barnase) CJ Paddon, RW Hartley Gene 40 (2-3), 231-239, 1985 | 56 | 1985 |
| Analysis of the localization of STE6/CFTR chimeras in a Saccharomyces cerevisiae model for the cystic fibrosis defect CFTRΔF508 C Paddon, D Loayza, L Vangelista, R Solari, S Michaelis Molecular microbiology 19 (5), 1007-1017, 1996 | 36 | 1996 |
| Translation and processing of Bacillus amyloliquefaciens extracellular RNase CJ Paddon, N Vasantha, RW Hartley Journal of bacteriology 171 (2), 1185-1187, 1989 | 32 | 1989 |
| Use of plasmid pTV1 in transposon mutagenesis and gene cloning in Bacillus amyloliquefaciens RW Hartley, CJ Paddon Plasmid 16 (1), 45-51, 1986 | 21 | 1986 |
| Exploring yeast glucans for vaccine enhancement: Sustainable strategies for overcoming adjuvant challenges in a SARS-CoV-2 model F Silva......Paddon, Fox European Journal of pharmaceutics and biopharmaceutics, 2024 | | 2024 |
