| ATP binding to the motor domain from an ABC transporter drives formation of a nucleotide sandwich dimer PC Smith, N Karpowich, L Millen, JE Moody, J Rosen, PJ Thomas, ... Molecular cell 10 (1), 139-149, 2002 | 1004 | 2002 |
| Defective protein folding as a basis of human disease PJ Thomas, BH Qu, PL Pedersen Trends in biochemical sciences 20 (11), 456-459, 1995 | 802 | 1995 |
| Quantum liquid droplets in a mixture of Bose-Einstein condensates CR Cabrera, L Tanzi, J Sanz, B Naylor, P Thomas, P Cheiney, L Tarruell Science 359 (6373), 301-304, 2018 | 756 | 2018 |
| Defining the disease liability of variants in the cystic fibrosis transmembrane conductance regulator gene PR Sosnay, KR Siklosi, F Van Goor, K Kaniecki, H Yu, N Sharma, ... Nature genetics 45 (10), 1160-1167, 2013 | 723 | 2013 |
| Dynamic association of proteasomal machinery with the centrosome W Christian Wigley, RP Fabunmi, MG Lee, CR Marino, S Muallem, ... The Journal of cell biology 145 (3), 481-490, 1999 | 633 | 1999 |
| Gating of CFTR by the STAS domain of SLC26 transporters SBH Ko, W Zeng, MR Dorwart, X Luo, KH Kim, L Millen, H Goto, S Naruse, ... Nature cell biology 6 (4), 343-350, 2004 | 528 | 2004 |
| Endoproteolytic activity of the proteasome CW Liu, MJ Corboy, GN DeMartino, PJ Thomas Science 299 (5605), 408-411, 2003 | 516 | 2003 |
| Aberrant CFTR-dependent HCO-3 transport in mutations associated with cystic fibrosis JY Choi, D Muallem, K Kiselyov, MG Lee, PJ Thomas, S Muallem Nature 410 (6824), 94-97, 2001 | 509 | 2001 |
| Structure of nucleotide‐binding domain 1 of the cystic fibrosis transmembrane conductance regulator HA Lewis, SG Buchanan, SK Burley, K Conners, M Dickey, M Dorwart, ... The EMBO journal 23 (2), 282-293, 2004 | 493 | 2004 |
| Cooperative, ATP-dependent association of the nucleotide binding cassettes during the catalytic cycle of ATP-binding cassette transporters JE Moody, L Millen, D Binns, JF Hunt, PJ Thomas Journal of Biological Chemistry 277 (24), 21111-21114, 2002 | 423 | 2002 |
| Crystal structures of the MJ1267 ATP binding cassette reveal an induced-fit effect at the ATPase active site of an ABC transporter N Karpowich, O Martsinkevich, L Millen, YR Yuan, PL Dai, K MacVey, ... Structure 9 (7), 571-586, 2001 | 395 | 2001 |
| A molecular mechanism for aberrantCFTR-dependent HCO3− transport in cystic fibrosis SBH Ko, N Shcheynikov, JY Choi, X Luo, K Ishibashi, PJ Thomas, JY Kim, ... The EMBO journal 21 (21), 5662-5672, 2002 | 383 | 2002 |
| A precipitating role for truncated α-synuclein and the proteasome in α-synuclein aggregation: implications for pathogenesis of Parkinson disease CW Liu, BI Giasson, KA Lewis, VM Lee, GN DeMartino, PJ Thomas Journal of Biological Chemistry 280 (24), 22670-22678, 2005 | 348 | 2005 |
| CFTR regulatory region interacts with NBD1 predominantly via multiple transient helices JMR Baker, RP Hudson, V Kanelis, WY Choy, PH Thibodeau, PJ Thomas, ... Nature structural & molecular biology 14 (8), 738-745, 2007 | 340 | 2007 |
| The crystal structure of the MJ0796 ATP-binding cassette: implications for the structural consequences of ATP hydrolysis in the active site of an ABC transporter YR Yuan, S Blecker, O Martsinkevich, L Millen, PJ Thomas, JF Hunt Journal of Biological Chemistry 276 (34), 32313-32321, 2001 | 334 | 2001 |
| Effects of joint lavage and steroid injection in patients with osteoarthritis of the knee: results of a multicenter, randomized, controlled trial P Ravaud, L Moulinier, B Giraudeau, X Ayral, C Guerin, E Noel, P Thomas, ... Arthritis & Rheumatism: Official Journal of the American College of …, 1999 | 310 | 1999 |
| Requirements for efficient correction of ΔF508 CFTR revealed by analyses of evolved sequences JL Mendoza, A Schmidt, Q Li, E Nuvaga, T Barrett, RJ Bridges, ... Cell 148 (1), 164-174, 2012 | 293 | 2012 |
| Nucleoplasmic bridges are a sensitive measure of chromosome rearrangement in the cytokinesis-block micronucleus assay P Thomas, K Umegaki, M Fenech Mutagenesis 18 (2), 187-194, 2003 | 291 | 2003 |
| Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis DM Hutt, D Herman, APC Rodrigues, S Noel, JM Pilewski, J Matteson, ... Nature chemical biology 6 (1), 25-33, 2010 | 289 | 2010 |
| CFTR modulator theratyping: Current status, gaps and future directions JP Clancy, CU Cotton, SH Donaldson, GM Solomon, DR VanDevanter, ... Journal of Cystic Fibrosis 18 (1), 22-34, 2019 | 286 | 2019 |
