Hydrogels with tunable stress relaxation regulate stem cell fate and activity O Chaudhuri, L Gu, D Klumpers, M Darnell, SA Bencherif, JC Weaver, ... Nature materials 15 (3), 326-334, 2016 | 2673* | 2016 |
Substrate stress relaxation regulates cell spreading O Chaudhuri, L Gu, M Darnell, D Klumpers, SA Bencherif, JC Weaver, ... Nature communications 6 (1), 6365, 2015 | 883 | 2015 |
Matrix elasticity of void-forming hydrogels controls transplanted-stem-cell-mediated bone formation N Huebsch, E Lippens, K Lee, M Mehta, ST Koshy, MC Darnell, RM Desai, ... Nature materials 14 (12), 1269-1277, 2015 | 507 | 2015 |
Performance and biocompatibility of extremely tough alginate/polyacrylamide hydrogels MC Darnell, JY Sun, M Mehta, C Johnson, PR Arany, Z Suo, DJ Mooney Biomaterials 34 (33), 8042-8048, 2013 | 378 | 2013 |
The CLEC-2–podoplanin axis controls the contractility of fibroblastic reticular cells and lymph node microarchitecture JL Astarita, V Cremasco, J Fu, MC Darnell, JR Peck, JM Nieves-Bonilla, ... Nature immunology 16 (1), 75-84, 2015 | 288 | 2015 |
Matrix viscoelasticity controls spatiotemporal tissue organization A Elosegui-Artola, A Gupta, AJ Najibi, BR Seo, R Garry, CM Tringides, ... Nature materials 22 (1), 117-127, 2023 | 164 | 2023 |
Substrate stress‐relaxation regulates scaffold remodeling and bone formation in vivo M Darnell, S Young, L Gu, N Shah, E Lippens, J Weaver, G Duda, ... Advanced healthcare materials 6 (1), 1601185, 2017 | 135 | 2017 |
Material microenvironmental properties couple to induce distinct transcriptional programs in mammalian stem cells M Darnell, A O’Neil, A Mao, L Gu, LL Rubin, DJ Mooney Proceedings of the National Academy of Sciences 115 (36), E8368-E8377, 2018 | 123 | 2018 |
Leveraging advances in biology to design biomaterials M Darnell, DJ Mooney Nature materials 16 (12), 1178-1185, 2017 | 123 | 2017 |
Injectable, tough alginate cryogels as cancer vaccines TY Shih, SO Blacklow, AW Li, BR Freedman, S Bencherif, ST Koshy, ... Advanced healthcare materials 7 (10), 1701469, 2018 | 121 | 2018 |
RNA-seq reveals diverse effects of substrate stiffness on mesenchymal stem cells M Darnell, L Gu, D Mooney Biomaterials 181, 182-188, 2018 | 99 | 2018 |
Skeletal muscle regeneration with robotic actuation–mediated clearance of neutrophils BR Seo, CJ Payne, SL McNamara, BR Freedman, BJ Kwee, S Nam, ... Science translational medicine 13 (614), eabe8868, 2021 | 74 | 2021 |
Switchable release of entrapped nanoparticles from alginate hydrogels CJ Kearney, H Skaat, SM Kennedy, J Hu, M Darnell, TM Raimondo, ... Advanced healthcare materials 4 (11), 1634, 2015 | 64 | 2015 |
Viscoelastic hydrogels with fast stress relaxation L Gu, O Chaudhuri, ND Huebsch, DJ Mooney, MC Darnell, S Young US Patent 11,065,362, 2021 | 12 | 2021 |
TRAFfic signals: High-throughput CAR discovery in NK cells reveals novel TRAF-binding endodomains that drive enhanced persistence and cytotoxicity MD Williams, AT Chen, MR Stone, L Guo, BJ Belmont, R Turk, N Bogard, ... bioRxiv, 2023.08. 02.551530, 2023 | 1 | 2023 |
Mechanotransduction Across Time and Length Scales MC Darnell Harvard University, 2017 | 1 | 2017 |
Viscoelastic hydrogels with fast stress relaxation L Gu, O Chaudhuri, ND Huebsch, DJ Mooney, MC Darnell, S Young US Patent 11,806,441, 2023 | | 2023 |
Identification of novel CAR transmembrane and endodomains for improved persistence and cytotoxicity of NK cell therapies M Williams, A Chen, M Stone, R Turk, N Kearns, N Bogard, L Guo, ... Cancer Research 83 (7_Supplement), 2911-2911, 2023 | | 2023 |
Switching circuits: Modulating NK cell response to TGF-β using novel receptors R Turk, L Guo, BJ Belmont, N Bogard, AT Chen, MD Williams, M Young, ... bioRxiv, 2023.12. 10.570687, 2023 | | 2023 |
An On-Demand Nanoparticle Delivery System for Precise Temporal Presentation of Bioagents CJ Kearney, H Skaat, SM Kennedy, J Hu, M Darnell, TM Raimondo, ... TISSUE ENGINEERING PART A 21, S332-S333, 2015 | | 2015 |