| Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression U Võsa, A Claringbould, HJ Westra, MJ Bonder, P Deelen, B Zeng, ... Nature genetics 53 (9), 1300-1310, 2021 | 1164 | 2021 |
| Whole-genome sequence variation, population structure and demographic history of the Dutch population Nature genetics 46 (8), 818-825, 2014 | 739 | 2014 |
| A comparison of automatic cell identification methods for single-cell RNA sequencing data T Abdelaal, L Michielsen, D Cats, D Hoogduin, H Mei, MJT Reinders, ... Genome biology 20, 1-19, 2019 | 548 | 2019 |
| Unraveling the polygenic architecture of complex traits using blood eQTL metaanalysis U Võsa, A Claringbould, HJ Westra, MJ Bonder, P Deelen, B Zeng, ... BioRxiv, 447367, 2018 | 516 | 2018 |
| Human-iPSC-derived cardiac stromal cells enhance maturation in 3D cardiac microtissues and reveal non-cardiomyocyte contributions to heart disease E Giacomelli, V Meraviglia, G Campostrini, A Cochrane, X Cao, ... Cell stem cell 26 (6), 862-879. e11, 2020 | 501 | 2020 |
| Disease variants alter transcription factor levels and methylation of their binding sites MJ Bonder, R Luijk, DV Zhernakova, M Moed, P Deelen, M Vermaat, ... Nature genetics 49 (1), 131-138, 2017 | 490 | 2017 |
| Identification of context-dependent expression quantitative trait loci in whole blood DV Zhernakova, P Deelen, M Vermaat, M Van Iterson, M Van Galen, ... Nature genetics 49 (1), 139-145, 2017 | 472 | 2017 |
| Genetic and environmental influences interact with age and sex in shaping the human methylome J Van Dongen, MG Nivard, G Willemsen, JJ Hottenga, Q Helmer, ... Nature communications 7 (1), 11115, 2016 | 390 | 2016 |
| Single-cell reconstruction of follicular remodeling in the human adult ovary X Fan, M Bialecka, I Moustakas, E Lam, V Torrens-Juaneda, ... Nature communications 10 (1), 3164, 2019 | 205 | 2019 |
| Blood lipids influence DNA methylation in circulating cells KF Dekkers, M van Iterson, RC Slieker, MH Moed, MJ Bonder, ... Genome biology 17, 1-12, 2016 | 199 | 2016 |
| DNA methylation analysis identifies loci for blood pressure regulation MA Richard, T Huan, S Ligthart, R Gondalia, MA Jhun, JA Brody, MR Irvin, ... The American Journal of Human Genetics 101 (6), 888-902, 2017 | 193 | 2017 |
| RNA sequencing data integration reveals an miRNA interactome of osteoarthritis cartilage RC de Almeida, YFM Ramos, A Mahfouz, W den Hollander, N Lakenberg, ... Annals of the rheumatic diseases 78 (2), 270-277, 2019 | 177 | 2019 |
| Improving phenotypic prediction by combining genetic and epigenetic associations S Shah, MJ Bonder, RE Marioni, Z Zhu, AF McRae, A Zhernakova, ... The American Journal of Human Genetics 97 (1), 75-85, 2015 | 162 | 2015 |
| Age-related accrual of methylomic variability is linked to fundamental ageing mechanisms RC Slieker, M van Iterson, R Luijk, M Beekman, DV Zhernakova, ... Genome biology 17, 1-13, 2016 | 150 | 2016 |
| Improved imputation quality of low-frequency and rare variants in European samples using the ‘Genome of The Netherlands’ P Deelen, A Menelaou, EM Van Leeuwen, A Kanterakis, F Van Dijk, ... European Journal of Human Genetics 22 (11), 1321-1326, 2014 | 127 | 2014 |
| Population-specific genotype imputations using minimac or IMPUTE2 EM Van Leeuwen, A Kanterakis, P Deelen, MV Kattenberg, PE Slagboom, ... Nature protocols 10 (9), 1285-1296, 2015 | 112 | 2015 |
| A high-quality human reference panel reveals the complexity and distribution of genomic structural variants JY Hehir-Kwa, T Marschall, WP Kloosterman, LC Francioli, JA Baaijens, ... Nature communications 7 (1), 12989, 2016 | 110 | 2016 |
| Refined mapping of autoimmune disease associated genetic variants with gene expression suggests an important role for non-coding RNAs I Ricaño-Ponce, DV Zhernakova, P Deelen, O Luo, X Li, A Isaacs, ... Journal of autoimmunity 68, 62-74, 2016 | 91 | 2016 |
| Genomic analysis reveals recurrent deletion of JAK‐STAT signaling inhibitors HNRNPK and SOCS1 in mycosis fungoides AN Bastidas Torres, D Cats, H Mei, K Szuhai, R Willemze, MH Vermeer, ... Genes, Chromosomes and Cancer 57 (12), 653-664, 2018 | 74 | 2018 |
| Retrospective validation of a metagenomic sequencing protocol for combined detection of RNA and DNA viruses using respiratory samples from pediatric patients S van Boheemen, AL van Rijn, N Pappas, EC Carbo, RHP Vorderman, ... The Journal of Molecular Diagnostics 22 (2), 196-207, 2020 | 72 | 2020 |
