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H. Tomas Rube
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The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer
RJA Bell, HT Rube, A Kreig, A Mancini, SD Fouse, RP Nagarajan, S Choi, ...
Science 348 (6238), 1036-1039, 2015
6062015
Understanding TERT promoter mutations: a common path to immortality
RJA Bell, HT Rube, A Xavier-Magalhaes, BM Costa, A Mancini, JS Song, ...
Molecular Cancer Research 14 (4), 315-323, 2016
3162016
General inflaton potentials in supergravity
R Kallosh, A Linde, T Rube
Physical Review D—Particles, Fields, Gravitation, and Cosmology 83 (4), 043507, 2011
2752011
Microbiota modulate transcription in the intestinal epithelium without remodeling the accessible chromatin landscape
JG Camp, CL Frank, CR Lickwar, H Guturu, T Rube, AM Wenger, J Chen, ...
Genome research 24 (9), 1504-1516, 2014
1432014
Chaotic inflation and supersymmetry breaking
R Kallosh, A Linde, KA Olive, T Rube
Physical Review D—Particles, Fields, Gravitation, and Cosmology 84 (8), 083519, 2011
1342011
Measuring DNA mechanics on the genome scale
A Basu, DG Bobrovnikov, Z Qureshi, T Kayikcioglu, TTM Ngo, A Ranjan, ...
Nature 589 (7842), 462-467, 2021
1252021
AsCas12a ultra nuclease facilitates the rapid generation of therapeutic cell medicines
L Zhang, JA Zuris, R Viswanathan, JN Edelstein, R Turk, B Thommandru, ...
Nature communications 12 (1), 3908, 2021
1202021
Accurate and sensitive quantification of protein-DNA binding affinity
C Rastogi, HT Rube, JF Kribelbauer, J Crocker, RE Loker, GD Martini, ...
Proceedings of the National Academy of Sciences 115 (16), E3692-E3701, 2018
1172018
Prediction of protein–ligand binding affinity from sequencing data with interpretable machine learning
HT Rube, C Rastogi, S Feng, JF Kribelbauer, A Li, B Becerra, LAN Melo, ...
Nature biotechnology 40 (10), 1520-1527, 2022
872022
Sequence features accurately predict genome-wide MeCP2 binding in vivo
HT Rube, W Lee, M Hejna, H Chen, DH Yasui, JF Hess, JM LaSalle, ...
Nature communications 7 (1), 11025, 2016
532016
A unified approach for quantifying and interpreting DNA shape readout by transcription factors
HT Rube, C Rastogi, JF Kribelbauer, HJ Bussemaker
Molecular systems biology 14 (2), e7902, 2018
452018
Systematic in vitro profiling of off-target affinity, cleavage and efficiency for CRISPR enzymes
L Zhang, HT Rube, CA Vakulskas, MA Behlke, HJ Bussemaker, MA Pufall
Nucleic acids research 48 (9), 5037-5053, 2020
392020
Nearly supersymmetric dark atoms
SR Behbahani, M Jankowiak, T Rube, JG Wacker
Advances in High Energy Physics 2011 (1), 709492, 2011
392011
SelexGLM differentiates androgen and glucocorticoid receptor DNA-binding preference over an extended binding site
L Zhang, GD Martini, HT Rube, JF Kribelbauer, C Rastogi, VD FitzPatrick, ...
Genome research 28 (1), 111-121, 2018
382018
Context-dependent gene regulation by homeodomain transcription factor complexes revealed by shape-readout deficient proteins
JF Kribelbauer, RE Loker, S Feng, C Rastogi, N Abe, HT Rube, ...
Molecular cell 78 (1), 152-167. e11, 2020
352020
𝒩= 8 Supergravity 4-point amplitudes
R Kallosh, CH Lee, T Rube
Journal of High Energy Physics 2009 (02), 050, 2009
302009
Boosting genome editing efficiency in human cells and plants with novel LbCas12a variants
L Zhang, G Li, Y Zhang, Y Cheng, N Roberts, SE Glenn, ...
Genome Biology 24 (1), 102, 2023
242023
Categorical spectral analysis of periodicity in nucleosomal DNA
H Jin, HT Rube, JS Song
Nucleic acids research 44 (5), 2047-2057, 2016
242016
Transcription factor paralogs orchestrate alternative gene regulatory networks by context-dependent cooperation with multiple cofactors
S Feng, C Rastogi, R Loker, WJ Glassford, H Tomas Rube, ...
Nature Communications 13 (1), 3808, 2022
232022
Quantitative analysis and prediction of G-quadruplex forming sequences in double-stranded DNA
M Kim, A Kreig, CY Lee, HT Rube, J Calvert, JS Song, S Myong
Nucleic acids research 44 (10), 4807-4817, 2016
232016
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