| Network biology concepts in complex disease comorbidities JX Hu, CE Thomas, S Brunak Nature Reviews Genetics 17 (10), 615-629, 2016 | 384 | 2016 |
| A deep learning algorithm to predict risk of pancreatic cancer from disease trajectories D Placido, B Yuan, JX Hjaltelin, C Zheng, AD Haue, PJ Chmura, C Yuan, ... Nature medicine 29 (5), 1113-1122, 2023 | 167 | 2023 |
| NetSig: network-based discovery from cancer genomes H Horn, MS Lawrence, CR Chouinard, Y Shrestha, JX Hu, E Worstell, ... Nature methods 15 (1), 61-66, 2018 | 107 | 2018 |
| Disease trajectory browser for exploring temporal, population-wide disease progression patterns in 7.2 million Danish patients T Siggaard, R Reguant, IF Jørgensen, AD Haue, M Lademann, ... Nature communications 11 (1), 4952, 2020 | 97 | 2020 |
| Randomized phase II study of nivolumab with or without ipilimumab combined with stereotactic body radiotherapy for refractory metastatic pancreatic cancer (CheckPAC) IM Chen, JS Johansen, S Theile, JX Hjaltelin, SI Novitski, S Brunak, ... Journal of Clinical Oncology 40 (27), 3180-3189, 2022 | 68 | 2022 |
| A large-cohort, longitudinal study determines precancer disease routes across different cancer types JX Hu, M Helleberg, AB Jensen, S Brunak, J Lundgren Cancer research 79 (4), 864-872, 2019 | 30 | 2019 |
| Comorbidity landscape of the Danish patient population affected by chromosome abnormalities IF Jørgensen, F Russo, AB Jensen, D Westergaard, M Lademann, JX Hu, ... Genetics in Medicine 21 (11), 2485-2495, 2019 | 19 | 2019 |
| Identification of hyper-rewired genomic stress non-oncogene addiction genes across 15 cancer types JX Hjaltelin, JMG Izarzugaza, LJ Jensen, F Russo, D Westergaard, ... NPJ Systems Biology and Applications, 2019 | 15 | 2019 |
| Pancreatic cancer risk predicted from disease trajectories using deep learning D Placido, B Yuan, JX Hjaltelin, AD Haue, PJ Chmura, C Yuan, J Kim, ... BioRxiv, 2021.06. 27.449937, 2021 | 14 | 2021 |
| A comparative analysis of network mutation burdens across 21 tumor types augments discovery from cancer genomes H Horn, MS Lawrence, JX Hu, E Worstell, N Ilic, Y Shrestha, E Kim, ... BioRxiv, 025445, 2015 | 11 | 2015 |
| Complete Topological Mapping of a Cellular Protein Interactome Reveals Bow-Tie Motifs as Ubiquitous Connectors of Protein Complexes K Niss, C Gomez-Casado, JX Hjaltelin, T Joeris, WW Agace, KG Belling, ... Cell Reports, 2020 | 7 | 2020 |
| Multi-cancer risk stratification based on national health data: a retrospective modelling and validation study AW Jung, PC Holm, K Gaurav, JX Hjaltelin, D Placido, LH Mortensen, ... The Lancet Digital Health 6 (6), e396-e406, 2024 | 6 | 2024 |
| Pancreatic cancer symptom trajectories from Danish registry data and free text in electronic health records JX Hjaltelin, SI Novitski, IF Jørgensen, T Siggaard, SA Vulpius, ... Elife 12, e84919, 2023 | 6 | 2023 |
| Reduced vitamin D-induced cathelicidin production and killing of Mycobacterium tuberculosis in macrophages from a patient with a non-functional vitamin D receptor: A case report FAH Al-Jaberi, CG Crone, T Lindenstrøm, NS Arildsen, ES Lindeløv, ... Frontiers in Immunology 13, 1038960, 2022 | 5 | 2022 |
| Visualising disease trajectories from population-wide data JX Hjaltelin, H Currant, IF Jørgensen, S Brunak Frontiers in Bioinformatics 3, 3, 2023 | 4 | 2023 |
| Plasma YKL-40 is associated with prognosis in patients with metastatic pancreatic cancer receiving immune checkpoint inhibitors in combination with radiotherapy AZ Johansen, SI Novitski, JX Hjaltelin, S Theile, MK Boisen, S Brunak, ... Frontiers in Immunology 14, 1228907, 2023 | 2 | 2023 |
| Bow-tie motifs enable protein multifunctionality by connecting cellular processes in the interactome K Niss, JX Hjaltelin, C Gomez-Casado, T Joeris, WW Agace, KG Belling, ... BioRxiv, 495895, 2018 | 2 | 2018 |
| Disease Trajectories from Healthcare Data: Methodologies, Key Results, and Future Perspectives IF Jørgensen, AD Haue, D Placido, JX Hjaltelin, S Brunak Annual review of biomedical data science 7 (1), 251-276, 2024 | 1 | 2024 |
| Randomized phase 2 study of nivolumab with or without ipilimumab in combination with stereotactic body radiotherapy in patients with refractory metastatic pancreatic cancer … IM Chen, JS Johansen, S Theile, JX Hjaltelin, SI Novitski, S Brunak, ... Journal of Clinical Oncology 40 (4_suppl), 554-554, 2022 | 1 | 2022 |
| Combing the hairball: Improving visualization of miRNA–target interaction networks F Russo, JX Hu, JA Romero Herrera, S Brunak MicroRNA target identification: Methods and protocols, 279-289, 2019 | 1 | 2019 |