Regulation of A disintegrin and metalloproteinase (ADAM) family sheddases ADAM10 and ADAM17: The emerging role of tetraspanins and rhomboids AL Matthews, PJ Noy, JS Reyat, MG Tomlinson Platelets 28 (4), 333-341, 2017 | 143 | 2017 |
The transcription factor encyclopedia D Yusuf, SL Butland, MI Swanson, E Bolotin, A Ticoll, WA Cheung, ... Genome biology 13, 1-25, 2012 | 141 | 2012 |
TspanC8 tetraspanins and a disintegrin and metalloprotease 10 (ADAM10) interact via their extracellular regions: evidence for distinct binding mechanisms for different TspanC8 … PJ Noy, J Yang, JS Reyat, AL Matthews, AE Charlton, J Furmston, ... Journal of Biological Chemistry 291 (7), 3145-3157, 2016 | 109 | 2016 |
Scissor sisters: regulation of ADAM10 by the TspanC8 tetraspanins AL Matthews, J Szyroka, R Collier, PJ Noy, MG Tomlinson Biochemical Society Transactions 45 (3), 719-730, 2017 | 86 | 2017 |
Multimerin-2 is a ligand for group 14 family C-type lectins CLEC14A, CD93 and CD248 spanning the endothelial pericyte interface KA Khan, AJ Naylor, A Khan, PJ Noy, M Mambretti, P Lodhia, J Athwal, ... Oncogene 36 (44), 6097-6108, 2017 | 81 | 2017 |
RhoJ interacts with the GIT–PIX complex and regulates focal adhesion disassembly E Wilson, K Leszczynska, NS Poulter, F Edelmann, VA Salisbury, PJ Noy, ... Journal of cell science 127 (14), 3039-3051, 2014 | 75 | 2014 |
Blocking CLEC14A-MMRN2 binding inhibits sprouting angiogenesis and tumour growth PJ Noy, P Lodhia, K Khan, X Zhuang, DG Ward, AR Verissimo, A Bacon, ... Oncogene 34 (47), 5821-5831, 2015 | 70 | 2015 |
TRPM7 kinase controls calcium responses in arterial thrombosis and stroke in mice SK Gotru, W Chen, P Kraft, IC Becker, K Wolf, S Stritt, S Zierler, ... Arteriosclerosis, thrombosis, and vascular biology 38 (2), 344-352, 2018 | 68 | 2018 |
PRH/Hhex controls cell survival through coordinate transcriptional regulation of vascular endothelial growth factor signaling P Noy, H Williams, A Sawasdichai, K Gaston, PS Jayaraman Molecular and cellular biology 30 (9), 2120-2134, 2010 | 56 | 2010 |
ADAM10-interacting tetraspanins Tspan5 and Tspan17 regulate VE-cadherin expression and promote T lymphocyte transmigration JS Reyat, M Chimen, PJ Noy, J Szyroka, G Rainger, MG Tomlinson The Journal of Immunology 199 (2), 666-676, 2017 | 51 | 2017 |
CK2 phosphorylation of the PRH/Hex homeodomain functions as a reversible switch for DNA binding A Soufi, P Noy, M Buckle, A Sawasdichai, K Gaston, PS Jayaraman Nucleic acids research 37 (10), 3288-3300, 2009 | 46 | 2009 |
The tetraspanin Tspan15 is an essential subunit of an ADAM10 scissor complex CZ Koo, N Harrison, PJ Noy, J Szyroka, AL Matthews, HE Hsia, SA Müller, ... Journal of Biological Chemistry 295 (36), 12822-12839, 2020 | 45 | 2020 |
Sprouting angiogenesis is regulated by shedding of the C‐type lectin family 14, member A (CLEC14A) ectodomain, catalyzed by rhomboid‐like 2 protein (RHBDL2) PJ Noy, RK Swain, K Khan, P Lodhia, R Bicknell The FASEB Journal 30 (6), 2311-2323, 2016 | 39 | 2016 |
Protein kinase CK2 inactivates PRH/Hhex using multiple mechanisms to de-repress VEGF-signalling genes and promote cell survival P Noy, A Sawasdichai, PS Jayaraman, K Gaston Nucleic acids research 40 (18), 9008-9020, 2012 | 38 | 2012 |
The metalloprotease ADAM10 (a disintegrin and metalloprotease 10) undergoes rapid, postlysis autocatalytic degradation T Brummer, M Pigoni, A Rossello, H Wang, PJ Noy, MG Tomlinson, ... The FASEB Journal 32 (7), 3560, 2018 | 37 | 2018 |
The PRH/Hex repressor protein causes nuclear retention of Groucho/TLE co-repressors C Desjobert, P Noy, T Swingler, H Williams, K Gaston, PS Jayaraman Biochemical Journal 417 (1), 121-132, 2009 | 32 | 2009 |
Tetraspanin Tspan9 regulates platelet collagen receptor GPVI lateral diffusion and activation EJ Haining, AL Matthews, PJ Noy, HM Romanska, HJ Harris, J Pike, ... Platelets 28 (7), 629-642, 2017 | 31 | 2017 |
Tspan18 is a novel regulator of the Ca2+ channel Orai1 and von Willebrand factor release in endothelial cells PJ Noy, RL Gavin, D Colombo, EJ Haining, JS Reyat, H Payne, ... Haematologica 104 (9), 1892, 2018 | 22 | 2018 |
Dasatinib inhibits leukaemic cell survival by decreasing PRH/Hhex phosphorylation resulting in increased repression of VEGF signalling genes P Noy, K Gaston, PS Jayaraman Leukemia research 36 (11), 1434-1437, 2012 | 15 | 2012 |
DNA compaction by the higher-order assembly of PRH/Hex homeodomain protein oligomers A Soufi, A Sawasdichai, A Shukla, P Noy, T Dafforn, C Smith, ... Nucleic acids research 38 (21), 7513-7525, 2010 | 9 | 2010 |