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Mark N Adams
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Structure, function and pathophysiology of protease activated receptors
MN Adams, R Ramachandran, MK Yau, JY Suen, DP Fairlie, ...
Pharmacology & therapeutics, 2011
4792011
Nucleophosmin: from structure and function to disease development
JK Box, N Paquet, MN Adams, D Boucher, E Bolderson, KJ O’Byrne, ...
BMC molecular biology 17, 1-12, 2016
3002016
Chemotherapeutic compounds targeting the DNA double-strand break repair pathways: the good, the bad, and the promising
C Jekimovs, E Bolderson, A Suraweera, M Adams, KJ O’Byrne, ...
Frontiers in oncology 4, 86, 2014
1442014
Proteolysis-induced n-terminal ectodomain shedding of the integral membrane glycoprotein CUB domain-containing protein 1 (CDCP1) is accompanied by tyrosine phosphorylation of …
Y He, A Wortmann, LJ Burke, JC Reid, MN Adams, I Abdul-Jabbar, ...
Journal of Biological Chemistry 285 (34), 26162-26173, 2010
862010
Expression of CDCA3 is a prognostic biomarker and potential therapeutic target in non–small cell lung cancer
MN Adams, JT Burgess, Y He, K Gately, C Snell, SD Zhang, JD Hooper, ...
Journal of Thoracic Oncology 12 (7), 1071-1084, 2017
792017
Epidermal growth factor receptor (EGFR)-mutated non-small-cell lung cancer (NSCLC)
C O’Leary, H Gasper, KB Sahin, M Tang, A Kulasinghe, MN Adams, ...
Pharmaceuticals 13 (10), 273, 2020
662020
The Role of Palmitoylation in Signalling, Cellular Trafficking and Plasma Membrane Localization of Protease-Activated Receptor-2
MN Adams, ME Christensen, Y He, NJ Waterhouse, JD Hooper
PLoS One 6 (11), e28018, 2011
632011
Cell line and patient-derived xenograft models reveal elevated CDCP1 as a target in high-grade serous ovarian cancer
BS Harrington, Y He, CM Davies, SJ Wallace, MN Adams, EA Beaven, ...
British journal of cancer 114 (4), 417-426, 2016
602016
Elevated CDCP1 predicts poor patient outcome and mediates ovarian clear cell carcinoma by promoting tumor spheroid formation, cell migration and chemoresistance
Y He, AC Wu, BS Harrington, CM Davies, SJ Wallace, MN Adams, ...
Oncogene 35 (4), 468-478, 2016
602016
Prostatic trypsin-like kallikrein-related peptidases (KLKs) and other prostate-expressed tryptic proteinases as regulators of signalling via proteinase-activated receptors (PARs)
AJ Ramsay, JC Reid, MN Adams, H Samaratunga, Y Dong, JA Clements, ...
Biological chemistry 389 (6), 653-668, 2008
552008
Barrier-to-autointegration factor 1 (Banf1) regulates poly [ADP-ribose] polymerase 1 (PARP1) activity following oxidative DNA damage
E Bolderson, JT Burgess, J Li, NS Gandhi, D Boucher, LV Croft, S Beard, ...
Nature communications 10 (1), 5501, 2019
502019
hSSB1 (NABP2/OBFC2B) is required for the repair of 8-oxo-guanine by the hOGG1-mediated base excision repair pathway
N Paquet, MN Adams, V Leong, NW Ashton, C Touma, R Gamsjaeger, ...
Nucleic acids research 43 (18), 8817-8829, 2015
492015
hSSB1 (NABP2/OBFC2B) is regulated by oxidative stress
N Paquet, MN Adams, NW Ashton, C Touma, R Gamsjaeger, L Cubeddu, ...
Scientific reports 6 (1), 27446, 2016
402016
EGF inhibits constitutive internalization and palmitoylation-dependent degradation of membrane-spanning procancer CDCP1 promoting its availability on the cell surface
MN Adams, BS Harrington, Y He, CM Davies, SJ Wallace, NP Chetty, ...
Oncogene 34 (11), 1375-1383, 2015
392015
Human single-stranded DNA binding protein 1 (hSSB1, OBFC2B), a critical component of the DNA damage response
LV Croft, E Bolderson, MN Adams, S El-Kamand, R Kariawasam, ...
Seminars in cell & developmental biology 86, 121-128, 2019
372019
CDCP1 enhances Wnt signaling in colorectal cancer promoting nuclear localization of β-catenin and E-cadherin
Y He, CM Davies, BS Harrington, L Hellmers, Y Sheng, A Broomfield, ...
Oncogene 39 (1), 219-233, 2020
342020
Transcriptomic profiling of cardiac tissues from SARS‐CoV‐2 patients identifies DNA damage
A Kulasinghe, N Liu, CW Tan, J Monkman, JE Sinclair, DD Bhuva, ...
Immunology 168 (3), 403-419, 2023
332023
Spatial profiling identifies prognostic features of response to adjuvant therapy in triple negative breast cancer (TNBC)
A Kulasinghe, J Monkman, ET Shah, N Matigian, MN Adams, K O’Byrne
Frontiers in Oncology 11, 798296, 2022
322022
Targeting NF-κB-mediated inflammatory pathways in cisplatin-resistant NSCLC
SL Ryan, S Beard, MP Barr, K Umezawa, S Heavey, P Godwin, SG Gray, ...
Lung Cancer 135, 217-227, 2019
322019
Activation and cleavage of SASH1 by caspase-3 mediates an apoptotic response
JT Burgess, E Bolderson, MN Adams, AM Baird, SD Zhang, KA Gately, ...
Cell death & disease 7 (11), e2469-e2469, 2016
312016
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