The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide S Viaud, F Saccheri, G Mignot, T Yamazaki, R Daillère, D Hannani, ... science 342 (6161), 971-976, 2013 | 2119 | 2013 |
Single-cell transcriptomics of human and mouse lung cancers reveals conserved myeloid populations across individuals and species R Zilionis, C Engblom, C Pfirschke, V Savova, D Zemmour, HD Saatcioglu, ... Immunity 50 (5), 1317-1334. e10, 2019 | 1245 | 2019 |
Cancer cell–autonomous contribution of type I interferon signaling to the efficacy of chemotherapy A Sistigu, T Yamazaki, E Vacchelli, K Chaba, DP Enot, J Adam, I Vitale, ... Nature medicine 20 (11), 1301-1309, 2014 | 1119 | 2014 |
Low-dose irradiation programs macrophage differentiation to an iNOS+/M1 phenotype that orchestrates effective T cell immunotherapy F Klug, H Prakash, PE Huber, T Seibel, N Bender, N Halama, C Pfirschke, ... Cancer cell 24 (5), 589-602, 2013 | 1084 | 2013 |
Immunogenic chemotherapy sensitizes tumors to checkpoint blockade therapy C Pfirschke, C Engblom, S Rickelt, V Cortez-Retamozo, C Garris, F Pucci, ... Immunity 44 (2), 343-354, 2016 | 970 | 2016 |
Successful anti-PD-1 cancer immunotherapy requires T cell-dendritic cell crosstalk involving the cytokines IFN-γ and IL-12 CS Garris, SP Arlauckas, RH Kohler, MP Trefny, S Garren, C Piot, ... Immunity 49 (6), 1148-1161. e7, 2018 | 905 | 2018 |
The role of myeloid cells in cancer therapies C Engblom, C Pfirschke, MJ Pittet Nature Reviews Cancer 16 (7), 447-462, 2016 | 779 | 2016 |
Tumour-associated macrophages act as a slow-release reservoir of nano-therapeutic Pt (IV) pro-drug MA Miller, YR Zheng, S Gadde, C Pfirschke, H Zope, C Engblom, ... Nature communications 6 (1), 1-13, 2015 | 465 | 2015 |
Osteoblasts remotely supply lung tumors with cancer-promoting SiglecFhigh neutrophils C Engblom, C Pfirschke, R Zilionis, J da Silva Martins, SA Bos, G Courties, ... Science 358 (6367), eaal5081, 2017 | 362 | 2017 |
Predicting therapeutic nanomedicine efficacy using a companion magnetic resonance imaging nanoparticle MA Miller, S Gadde, C Pfirschke, C Engblom, MM Sprachman, RH Kohler, ... Science translational medicine 7 (314), 314ra183-314ra183, 2015 | 359 | 2015 |
SCS macrophages suppress melanoma by restricting tumor-derived vesicle–B cell interactions F Pucci, C Garris, CP Lai, A Newton, C Pfirschke, C Engblom, D Alvarez, ... Science 352 (6282), 242-246, 2016 | 343 | 2016 |
Author correction: crizotinib-induced immunogenic cell death in non-small cell lung cancer P Liu, L Zhao, J Pol, S Levesque, A Petrazzuolo, C Pfirschke, C Engblom, ... Nature Communications 10 (1), 1-1, 2019 | 270* | 2019 |
Crizotinib-induced immunogenic cell death in non-small cell lung cancer P Liu, L Zhao, J Pol, S Levesque, A Petrazzuolo, C Pfirschke, C Engblom, ... Nature communications 10 (1), 1-17, 2019 | 265 | 2019 |
Durable and controlled depletion of neutrophils in mice G Boivin, J Faget, PB Ancey, A Gkasti, J Mussard, C Engblom, C Pfirschke, ... Nature communications 11 (1), 1-9, 2020 | 246 | 2020 |
Radiation therapy primes tumors for nanotherapeutic delivery via macrophage-mediated vascular bursts MA Miller, R Chandra, MF Cuccarese, C Pfirschke, C Engblom, ... Science translational medicine 9 (392), eaal0225, 2017 | 225 | 2017 |
Heterogeneity of macrophage infiltration and therapeutic response in lung carcinoma revealed by 3D organ imaging MF Cuccarese, JM Dubach, C Pfirschke, C Engblom, C Garris, MA Miller, ... Nature communications 8 (1), 1-10, 2017 | 181 | 2017 |
PF4 promotes platelet production and lung cancer growth F Pucci, S Rickelt, AP Newton, C Garris, E Nunes, C Evavold, C Pfirschke, ... Cell reports 17 (7), 1764-1772, 2016 | 111 | 2016 |
Tumor-promoting Ly-6G+ SiglecFhigh cells are mature and long-lived neutrophils C Pfirschke, C Engblom, J Gungabeesoon, Y Lin, S Rickelt, R Zilionis, ... Cell reports 32 (12), 108164, 2020 | 99 | 2020 |
Immune-dependent antineoplastic effects of cisplatin plus pyridoxine in non-small-cell lung cancer F Aranda, N Bloy, J Pesquet, B Petit, K Chaba, A Sauvat, O Kepp, ... Oncogene 34 (23), 3053-3062, 2015 | 86 | 2015 |
Coexpression of the T-cell receptor constant α domain triggers tumor reactivity of single-chain TCR-transduced human T cells RH Voss, S Thomas, C Pfirschke, B Hauptrock, S Klobuch, J Kuball, ... Blood, The Journal of the American Society of Hematology 115 (25), 5154-5163, 2010 | 77 | 2010 |