Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies NA Doria-Rose, CA Schramm, J Gorman, PL Moore, JN Bhiman, ... Nature 509 (7498), 55-62, 2014 | 818 | 2014 |
Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G GBE Stewart-Jones, C Soto, T Lemmin, GY Chuang, A Druz, R Kong, ... Cell 165 (4), 813-826, 2016 | 444 | 2016 |
Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody R Kong, K Xu, T Zhou, P Acharya, T Lemmin, K Liu, G Ozorowski, C Soto, ... Science 352 (6287), 828-833, 2016 | 361 | 2016 |
Structural repertoire of HIV-1-neutralizing antibodies targeting the CD4 supersite in 14 donors T Zhou, RM Lynch, L Chen, P Acharya, X Wu, NA Doria-Rose, MG Joyce, ... Cell 161 (6), 1280-1292, 2015 | 342 | 2015 |
Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody M Bonsignori, T Zhou, Z Sheng, L Chen, F Gao, MG Joyce, G Ozorowski, ... Cell 165 (2), 449-463, 2016 | 338 | 2016 |
Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1 K Xu, P Acharya, R Kong, C Cheng, GY Chuang, K Liu, MK Louder, ... Nature medicine 24 (6), 857, 2018 | 301 | 2018 |
Envelope residue 375 substitutions in simian–human immunodeficiency viruses enhance CD4 binding and replication in rhesus macaques H Li, S Wang, R Kong, W Ding, FH Lee, Z Parker, E Kim, GH Learn, ... Proceedings of the National Academy of Sciences 113 (24), E3413-E3422, 2016 | 228 | 2016 |
Optimal combinations of broadly neutralizing antibodies for prevention and treatment of HIV-1 clade C infection K Wagh, T Bhattacharya, C Williamson, A Robles, M Bayne, J Garrity, ... PLoS pathogens 12 (3), e1005520, 2016 | 206 | 2016 |
Improving Neutralization potency and breadth by combining broadly reactive HIV-1 antibodies targeting major neutralization epitopes R Kong, MK Louder, K Wagh, RT Bailer, K Greene, H Gao, JD Taft, ... Journal of virology 89 (5), 2659-2671, 2015 | 149 | 2015 |
Functional interrogation and mining of natively paired human VH:VL antibody repertoires B Wang, BJ DeKosky, MR Timm, J Lee, E Normandin, J Misasi, R Kong, ... Nature biotechnology 36 (2), 152, 2018 | 143 | 2018 |
Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization R Kong, H Duan, Z Sheng, K Xu, P Acharya, X Chen, C Cheng, ... Cell 178 (3), 567-584. e19, 2019 | 120 | 2019 |
A neutralizing antibody recognizing primarily N-linked glycan targets the silent face of the HIV envelope T Zhou, A Zheng, U Baxa, GY Chuang, IS Georgiev, R Kong, S O’Dell, ... Immunity 48 (3), 500-513. e6, 2018 | 88 | 2018 |
Gene-specific substitution profiles describe the types and frequencies of amino acid changes during antibody somatic hypermutation Z Sheng, CA Schramm, R Kong, JC Mullikin, JR Mascola, PD Kwong, ... Frontiers in immunology 8, 537, 2017 | 86 | 2017 |
Broad and potent neutralizing antibody responses elicited in natural HIV-2 infection R Kong, H Li, F Bibollet-Ruche, JM Decker, NN Zheng, GS Gottlieb, ... Journal of virology 86 (2), 947-960, 2012 | 78 | 2012 |
Mapping Polyclonal HIV-1 Antibody Responses via Next-Generation Neutralization Fingerprinting NA Doria-Rose, HR Altae-Tran, RS Roark, SD Schmidt, MS Sutton, ... PLoS pathogens 13 (1), e1006148, 2017 | 62 | 2017 |
Consistent elicitation of cross-clade HIV-neutralizing responses achieved in guinea pigs after fusion peptide priming by repetitive envelope trimer boosting C Cheng, K Xu, R Kong, GY Chuang, AR Corrigan, H Geng, KR Hill, ... PloS one 14 (4), e0215163, 2019 | 48 | 2019 |
Preclinical development of a fusion peptide conjugate as an HIV vaccine immunogen L Ou, WP Kong, GY Chuang, M Ghosh, K Gulla, S O’Dell, J Varriale, ... Scientific reports 10 (1), 1-13, 2020 | 41 | 2020 |
Epitope mapping of broadly neutralizing human HIV-2 monoclonal antibodies R Kong, H Li, I Georgiev, A Changela, F Bibollet-Ruche, JM Decker, ... Journal of Virology, 2012 | 35* | 2012 |
Development of a 3mut-apex-stabilized envelope trimer that expands HIV-1 neutralization breadth when used to boost fusion peptide-directed vaccine-elicited responses GY Chuang, YT Lai, JC Boyington, C Cheng, H Geng, S Narpala, R Rawi, ... Journal of virology 94 (13), e00074-20, 2020 | 28 | 2020 |
Mutational fitness landscapes reveal genetic and structural improvement pathways for a vaccine-elicited HIV-1 broadly neutralizing antibody B Madan, B Zhang, K Xu, CW Chao, S O’Dell, JR Wolfe, GY Chuang, ... Proceedings of the National Academy of Sciences 118 (10), 2021 | 24 | 2021 |