| TIA1 prevents skipping of a critical exon associated with spinal muscular atrophy NN Singh, J Seo, EW Ottesen, M Shishimorova, D Bhattacharya, ... Molecular and cellular biology 31 (5), 935-954, 2011 | 105 | 2011 |
| Spinal muscular atrophy: an update on therapeutic progress J Seo, MD Howell, NN Singh, RN Singh Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1832 (12 …, 2013 | 81 | 2013 |
| Severe impairment of male reproductive organ development in a low SMN expressing mouse model of spinal muscular atrophy EW Ottesen, MD Howell, NN Singh, J Seo, EM Whitley, RN Singh Scientific Reports, 2016 | 77 | 2016 |
| A multi-exon-skipping detection assay reveals surprising diversity of splice isoforms of spinal muscular atrophy genes NN Singh, J Seo, SJ Rahn, RN Singh PLoS One 7 (11), e49595, 2012 | 74 | 2012 |
| Human Survival Motor Neuron genes generate a vast repertoire of circular RNAs EW Ottesen, D Luo, J Seo, NN Singh, RN Singh Nucleic acids research 47 (6), 2884-2905, 2019 | 73 | 2019 |
| A novel human-specific splice isoform alters the critical C-terminus of Survival Motor Neuron protein J Seo, NN Singh, EW Ottesen, BM Lee, RN Singh Scientific reports 6 (1), 30778, 2016 | 63 | 2016 |
| Oxidative stress triggers body-wide skipping of multiple exons of the spinal muscular atrophy gene J Seo, NN Singh, EW Ottesen, S Sivanesan, M Shishimorova, RN Singh PloS one 11 (4), e0154390, 2016 | 57 | 2016 |
| A short antisense oligonucleotide ameliorates symptoms of severe mouse models of spinal muscular atrophy JM Keil, J Seo, MD Howell, WH Hsu, RN Singh, CJ DiDonato Molecular Therapy-Nucleic Acids 3, 2014 | 56 | 2014 |
| Understanding BRCA2 function as a tumor suppressor based on domain-specific activities in DNA damage responses PR Andreassen, J Seo, C Wiek, H Hanenberg Genes 12 (7), 1034, 2021 | 45 | 2021 |
| Hepatic Ago2-mediated RNA silencing controls energy metabolism linked to AMPK activation and obesity-associated pathophysiology C Zhang, J Seo, K Murakami, ESB Salem, E Bernhard, VJ Borra, K Choi, ... Nature communications 9 (1), 3658, 2018 | 43 | 2018 |
| A Multilayered Control of the Human Survival Motor Neuron Gene Expression by Alu Elements EW Ottesen, J Seo, NN Singh, RN Singh Frontiers in Microbiology 8, 2252, 2017 | 42 | 2017 |
| TIA1 is a gender-specific disease modifier of a mild mouse model of spinal muscular atrophy MD Howell, EW Ottesen, NN Singh, RL Anderson, J Seo, S Sivanesan, ... Scientific reports 7 (1), 7183, 2017 | 36 | 2017 |
| Diverse targets of SMN2-directed splicing-modulating small molecule therapeutics for spinal muscular atrophy EW Ottesen, NN Singh, D Luo, B Kaas, BJ Gillette, J Seo, HJ Jorgensen, ... Nucleic Acids Research 51 (12), 5948-5980, 2023 | 26 | 2023 |
| RNA in spinal muscular atrophy: therapeutic implications of targeting RN Singh, J Seo, NN Singh Expert opinion on therapeutic targets 24 (8), 731-743, 2020 | 26 | 2020 |
| Antisense methods to modulate pre-mRNA splicing J Seo, EW Ottesen, RN Singh Spliceosomal Pre-mRNA Splicing: Methods and Protocols, 271-283, 2014 | 22 | 2014 |
| A super minigene with a short promoter and truncated introns recapitulates essential features of transcription and splicing regulation of the SMN1 and SMN2 genes EW Ottesen, J Seo, D Luo, NN Singh, RN Singh Nucleic Acids Research 52 (7), 3547-3571, 2024 | 5 | 2024 |
| Cellular approaches in investigating Argonaute2-dependent RNA silencing C Zhang, J Seo, T Nakamura Argonaute Proteins: Methods and Protocols, 205-215, 2018 | 2 | 2018 |
| Identification of splicing cis‐elements through an ultra‐refined antisense microwalk NN Singh, J Seo, RN Singh Alternative Pre‐mRNA Splicing: theory and Protocols, 210-217, 2012 | 2 | 2012 |
| U1 snRNA interactions with deep intronic sequences regulate splicing of multiple exons of spinal muscular atrophy genes EW Ottesen, NN Singh, J Seo, RN Singh Frontiers in Neuroscience 18, 1412893, 2024 | | 2024 |
| Severe impairment of male reproductive organ development in a low SMN expressing mouse model of spinal muscular atrophy R Singh, M Howell, N Singh, J Seo, E Whitley, E Ottesen | | 2016 |
