The antiparasitic drug ivermectin is a novel FXR ligand that regulates metabolism L Jin, X Feng, H Rong, Z Pan, Y Inaba, L Qiu, W Zheng, S Lin, R Wang, ... Nature communications 4 (1), 1937, 2013 | 166 | 2013 |
STIM1 overexpression promotes colorectal cancer progression, cell motility and COX-2 expression JY Wang, J Sun, MY Huang, YS Wang, MF Hou, Y Sun, H He, N Krishna, ... Oncogene 34 (33), 4358-4367, 2015 | 156 | 2015 |
Fascin controls metastatic colonization and mitochondrial oxidative phosphorylation by remodeling mitochondrial actin filaments S Lin, C Huang, V Gunda, J Sun, SP Chellappan, Z Li, V Izumi, B Fang, ... Cell reports 28 (11), 2824-2836. e8, 2019 | 74 | 2019 |
Mitochondrial calcium uniporter drives metastasis and confers a targetable cystine dependency in pancreatic cancer X Wang, Y Li, Z Li, S Lin, H Wang, J Sun, C Lan, L Wu, D Sun, C Huang, ... Cancer research 82 (12), 2254-2268, 2022 | 70 | 2022 |
How does fascin promote cancer metastasis? S Lin, MD Taylor, PK Singh, S Yang The FEBS journal 288 (5), 1434-1446, 2021 | 61 | 2021 |
Fascin promotes lung cancer growth and metastasis by enhancing glycolysis and PFKFB3 expression S Lin, Y Li, D Wang, C Huang, D Marino, O Bollt, C Wu, MD Taylor, W Li, ... Cancer letters 518, 230-242, 2021 | 57 | 2021 |
Monoubiquitination inhibits the actin bundling activity of fascin S Lin, S Lu, M Mulaj, B Fang, T Keeley, L Wan, J Hao, M Muschol, J Sun, ... Journal of Biological Chemistry 291 (53), 27323-27333, 2016 | 45 | 2016 |
Identification of an oleanane-type triterpene hedragonic acid as a novel farnesoid X receptor ligand with liver protective effects and anti-inflammatory activity Y Lu, W Zheng, S Lin, F Guo, Y Zhu, Y Wei, X Liu, S Jin, L Jin, Y Li Molecular pharmacology 93 (2), 63-72, 2018 | 36 | 2018 |
Structural basis for iloprost as a dual peroxisome proliferator-activated receptor α/δ agonist L Jin, S Lin, H Rong, S Zheng, S Jin, R Wang, Y Li Journal of Biological Chemistry 286 (36), 31473-31479, 2011 | 35 | 2011 |
The mitochondrial deoxyguanosine kinase is required for cancer cell stemness in lung adenocarcinoma S Lin, C Huang, J Sun, O Bollt, X Wang, E Martine, J Kang, MD Taylor, ... EMBO molecular medicine 11 (12), e10849, 2019 | 34 | 2019 |
Identification of the antibiotic ionomycin as an unexpected peroxisome proliferator-activated receptor γ (PPARγ) ligand with a unique binding mode and effective glucose … W Zheng, X Feng, L Qiu, Z Pan, R Wang, S Lin, D Hou, L Jin, Y Li Diabetologia 56, 401-411, 2013 | 34 | 2013 |
Revealing a natural marine product as a novel agonist for retinoic acid receptors with a unique binding mode and inhibitory effects on cancer cells S Wang, Z Wang, S Lin, W Zheng, R Wang, S Jin, J Chen, L Jin, Y Li Biochemical Journal 446 (1), 79-87, 2012 | 24 | 2012 |
Revealing a steroid receptor ligand as a unique PPARγ agonist S Lin, Y Han, Y Shi, H Rong, S Zheng, S Jin, SY Lin, SC Lin, Y Li Cell research 22 (4), 746-756, 2012 | 24 | 2012 |
A novel class of natural fxr modulators with a unique mode of selective co‐regulator assembly W Zheng, Y Lu, S Lin, R Wang, L Qiu, Y Zhu, B Yao, F Guo, S Jin, L Jin, ... ChemBioChem 18 (8), 721-725, 2017 | 21 | 2017 |
The fucose salvage pathway inhibits invadopodia formation and extracellular matrix degradation in melanoma cells T Keeley, S Lin, DK Lester, EK Lau, S Yang PloS one 13 (6), e0199128, 2018 | 17 | 2018 |
AXIN is an essential co-activator for the promyelocytic leukemia protein in p53 activation Q Li, Y He, L Wei, X Wu, D Wu, S Lin, Z Wang, Z Ye, SC Lin Oncogene 30 (10), 1194-1204, 2011 | 16 | 2011 |
Disseminating melanoma cells surf on calcium waves J Sun, S Lin, T Keeley, S Yang Molecular & cellular oncology 2 (4), e1002714, 2015 | 8 | 2015 |
Characterization of human placenta-derived exosome (pExo) as a potential osteoarthritis disease modifying therapeutic C Huang, Y Zhao, S Lin, L Li, X Guo, S Yumiseba, J Yang, R Hariri, Q Ye, ... Arthritis Research & Therapy 25 (1), 229, 2023 | 4 | 2023 |
Spatiotemporal regulation of store-operated calcium entry in cancer metastasis F Lu, Y Li, S Lin, H Cheng, S Yang Biochemical Society Transactions 49 (6), 2581-2589, 2021 | 4 | 2021 |
Characterization of CRISPR/Cas9-edited human placental allogenic stromal cells with low tissue factor expression and reduced thrombotic effects C Huang, Y Zhao, Q Ye, J Gleason, V Rousseva, B Stout, S Lin, R Hariri, ... Cytotherapy 25 (12), 1265-1270. e2, 2023 | 2 | 2023 |