| Application of cardiac electrophysiology simulations to pro‐arrhythmic safety testing GR Mirams, MR Davies, Y Cui, P Kohl, D Noble British journal of pharmacology 167 (5), 932-945, 2012 | 118 | 2012 |
| Prediction of thorough QT study results using action potential simulations based on ion channel screens GR Mirams, MR Davies, SJ Brough, MH Bridgland-Taylor, Y Cui, ... Journal of pharmacological and toxicological methods 70 (3), 246-254, 2014 | 104 | 2014 |
| Variability in high-throughput ion-channel screening data and consequences for cardiac safety assessment RC Elkins, MR Davies, SJ Brough, DJ Gavaghan, Y Cui, N Abi-Gerges, ... Journal of pharmacological and toxicological methods 68 (1), 112-122, 2013 | 97 | 2013 |
| An in silico canine cardiac midmyocardial action potential duration model as a tool for early drug safety assessment MR Davies, HB Mistry, L Hussein, CE Pollard, JP Valentin, J Swinton, ... American Journal of Physiology-Heart and Circulatory Physiology 302 (7 …, 2012 | 92 | 2012 |
| High-throughput screening of drug-binding dynamics to HERG improves early drug safety assessment GY Di Veroli, MR Davies, H Zhang, N Abi-Gerges, MR Boyett American Journal of Physiology-Heart and Circulatory Physiology 304 (1 …, 2013 | 88 | 2013 |
| Harvesting the promise of AOPs: An assessment and recommendations A Carusi, MR Davies, G De Grandis, BI Escher, G Hodges, KMY Leung, ... Science of the Total Environment 628, 1542-1556, 2018 | 84 | 2018 |
| Recent developments in using mechanistic cardiac modelling for drug safety evaluation MR Davies, K Wang, GR Mirams, A Caruso, D Noble, A Walz, T Lavé, ... Drug discovery today 21 (6), 924-938, 2016 | 82 | 2016 |
| hERG inhibitors with similar potency but different binding kinetics do not pose the same proarrhythmic risk: implications for drug safety assessment GY Di Veroli, MR Davies, H Zhang, N ABI‐GERGES, MR Boyett Journal of cardiovascular electrophysiology 25 (2), 197-207, 2014 | 76 | 2014 |
| Capacity limits of asialoglycoprotein receptor-mediated liver targeting C Bon, T Hofer, A Bousquet-Mélou, MR Davies, BF Krippendorff MAbs 9 (8), 1360-1369, 2017 | 69 | 2017 |
| The Na+/K+ pump is an important modulator of refractoriness and rotor dynamics in human atrial tissue C Sánchez, A Corrias, A Bueno-Orovio, M Davies, J Swinton, I Jacobson, ... American Journal of Physiology-Heart and Circulatory Physiology 302 (5 …, 2012 | 57 | 2012 |
| Nurr1 dependent regulation of pro-inflammatory mediators in immortalised synovial fibroblasts MR Davies, CJ Harding, S Raines, K Tolley, AE Parker, M Downey-Jones, ... Journal of Inflammation 2 (1), 15, 2005 | 54 | 2005 |
| Human-based approaches to pharmacology and cardiology: an interdisciplinary and intersectorial workshop B Rodriguez, A Carusi, N Abi-Gerges, R Ariga, O Britton, G Bub, ... Ep Europace 18 (9), 1287-1298, 2015 | 53 | 2015 |
| Ligands for retinoic acid receptors are elevated in osteoarthritis and may contribute to pathologic processes in the osteoarthritic joint MR Davies, LR Ribeiro, M Downey‐Jones, MRC Needham, C Oakley, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2009 | 45 | 2009 |
| Methodologies for quantitative systems pharmacology (QSP) models: design and estimation B Ribba, HP Grimm, B Agoram, MR Davies, K Gadkar, S Niederer, ... CPT: pharmacometrics & systems pharmacology 6 (8), 496-498, 2017 | 40 | 2017 |
| Nuclear hormone receptor-dependent regulation of hepatic transporters and their role in the adaptive response in cholestasis S Stahl, MR Davies, DI Cook, MJ Graham Xenobiotica 38 (7-8), 725-777, 2008 | 38 | 2008 |
| A new classifier-based strategy for in-silico ion-channel cardiac drug safety assessment HB Mistry, MR Davies, GY Di Veroli Frontiers in pharmacology 6, 59, 2015 | 29 | 2015 |
| Hierarchical Bayesian modelling of variability and uncertainty in synthetic action potential traces RH Johnstone, R Bardenet, DJ Gavaghan, L Polonchuk, MR Davies, ... 2016 Computing in Cardiology Conference (CinC), 1089-1092, 2016 | 13 | 2016 |
| Use of Patient Health Records to Quantify Drug-Related Pro-arrhythmic Risk MR Davies, M Martinec, R Walls, R Schwarz, GR Mirams, K Wang, ... Cell Reports Medicine 1 (5), 100076, 2020 | 6 | 2020 |
| Hierarchical Bayesian fitting of concentration-effect models to ion channel screening data R Johnstone, R Bardenet, L Polonchuk, M Davies, D Gavaghan, ... Journal of Pharmacological and Toxicological Methods 88, 198, 2017 | 1 | 2017 |
| Cardiac DJ Gallacher, G Gintant, N Abi‐Gerges, MR Davies, HR Lu, KM Hoagland, ... Drug Discovery Toxicology: From Target Assessment to Translational …, 2016 | 1 | 2016 |
Gary MiramsCentre for Mathematical Medicine & Biology, University of NottinghamVerified email at nottingham.ac.uk