| Extrasynaptic NMDA receptors couple preferentially to excitotoxicity via calpain-mediated cleavage of STEP J Xu, P Kurup, Y Zhang, SM Goebel-Goody, PH Wu, AH Hawasli, ... Journal of Neuroscience 29 (29), 9330-9343, 2009 | 346 | 2009 |
| The role of STEP in Alzheimer's disease PJL Pradeep Kurup, Yongfang Zhang, Deepa V Venkitaramani, Jian Xu Channels (Austin) 4 (5), 347-350, 2010 | 279* | 2010 |
| Aβ-mediated NMDA receptor endocytosis in Alzheimer's disease involves ubiquitination of the tyrosine phosphatase STEP61 P Kurup, Y Zhang, J Xu, DV Venkitaramani, V Haroutunian, P Greengard, ... The Journal of Neuroscience 30 (17), 5948-5957, 2010 | 257 | 2010 |
| Genetic reduction of striatal-enriched tyrosine phosphatase (STEP) reverses cognitive and cellular deficits in an Alzheimer’s disease mouse model Y Zhang, P Kurup, J Xu, N Carty, SM Fernandez, HB Nygaard, C Pittenger, ... Proceedings of the National Academy of Sciences 107 (44), 19014-19019, 2010 | 204 | 2010 |
| Potentiation of synaptic GluN2B NMDAR currents by Fyn kinase is gated through BDNF-mediated disinhibition in spinal pain processing ME Hildebrand, J Xu, A Dedek, Y Li, AS Sengar, S Beggs, PJ Lombroso, ... Cell reports 17 (10), 2753-2765, 2016 | 150 | 2016 |
| Inhibitor of the tyrosine phosphatase STEP reverses cognitive deficits in a mouse model of Alzheimer's disease J Xu, M Chatterjee, TD Baguley, J Brouillette, P Kurup, D Ghosh, J Kanyo, ... PLoS biology 12 (8), e1001923, 2014 | 150 | 2014 |
| Antibodies from children with PANDAS bind specifically to striatal cholinergic interneurons and alter their activity J Xu, RJ Liu, S Fahey, L Frick, J Leckman, F Vaccarino, RS Duman, ... American Journal of Psychiatry 178 (1), 48-64, 2021 | 103 | 2021 |
| Calpain and STriatal-Enriched protein tyrosine Phosphatase (STEP) activation contribute to extrasynaptic NMDA receptor localization in a Huntington's disease mouse model CM Gladding, MD Sepers, J Xu, LYJ Zhang, AJ Milnerwood, PJ Lombroso, ... Human Molecular Genetics 21 (17), 3739-3752, 2012 | 96 | 2012 |
| Striatal-enriched Protein-tyrosine Phosphatase (STEP) Regulates Pyk2 Kinase Activity J Xu, P Kurup, JA Bartos, T Patriarchi, JW Hell, PJ Lombroso Journal of Biological Chemistry 287 (25), 20942-20956, 2012 | 93 | 2012 |
| The tyrosine phosphatase STEP: implications in schizophrenia and the molecular mechanism underlying antipsychotic medications NC Carty, J Xu, P Kurup, J Brouillette, SM Goebel-Goody, DR Austin, ... Translational Psychiatry 2 (7), e137, 2012 | 91 | 2012 |
| Striatal-enriched protein tyrosine phosphatase expression and activity in Huntington's disease: a STEP in the resistance to excitotoxicity A Saavedra, A Giralt, L Rué, X Xifró, J Xu, Z Ortega, JJ Lucas, ... Journal of Neuroscience 31 (22), 8150-8162, 2011 | 78 | 2011 |
| Striatal-enriched protein tyrosine phosphatase—STEPs toward understanding chronic stress-induced activation of corticotrophin releasing factor neurons in the rat bed nucleus … J Dabrowska, R Hazra, JD Guo, CC Li, S DeWitt, J Xu, PJ Lombroso, ... Biological psychiatry 74 (11), 817-826, 2013 | 71 | 2013 |
| Reduced levels of the tyrosine phosphatase STEP block beta amyloid‐mediated GluA1/GluA2 receptor internalization Y Zhang, P Kurup, J Xu, GM Anderson, P Greengard, AC Nairn, ... Journal of neurochemistry 119 (3), 664-672, 2011 | 68 | 2011 |
| Loss of STEP61 couples disinhibition to N-methyl-d-aspartate receptor potentiation in rodent and human spinal pain processing A Dedek, J Xu, CM Kandegedara, LÉ Lorenzo, AG Godin, Y De Koninck, ... Brain 142 (6), 1535-1546, 2019 | 66 | 2019 |
| Characterization of human LNX, a novel ligand of Numb protein X that is downregulated in human gliomas J Chen, J Xu, W Zhao, G Hu, H Cheng, Y Kang, Y Xie, Y Lu The international journal of biochemistry & cell biology 37 (11), 2273-2283, 2005 | 65 | 2005 |
| STEP61 is a substrate of the E3 ligase parkin and is upregulated in Parkinson’s disease PK Kurup, J Xu, RA Videira, C Ononenyi, G Baltazar, PJ Lombroso, ... Proceedings of the National Academy of Sciences 112 (4), 1202-1207, 2015 | 63 | 2015 |
| Identification of a novel human angiopoietin-like gene expressed mainly in heart L Zeng, J Dai, K Ying, E Zhao, W Jin, Y Ye, J Dai, J Xu, Y Xie, Y Mao Journal of human genetics 48 (3), 159-162, 2003 | 61 | 2003 |
| A novel splice variant of the cell adhesion molecule contactin 4 (CNTN4) is mainly expressed in human brain L Zeng, C Zhang, J Xu, X Ye, Q Wu, J Dai, C Ji, S Gu, Y Xie, Y Mao Journal of human genetics 47 (9), 497-499, 2002 | 60 | 2002 |
| Sexual dimorphism in a neuronal mechanism of spinal hyperexcitability across rodent and human models of pathological pain A Dedek, J Xu, LÉ Lorenzo, AG Godin, CM Kandegedara, G Glavina, ... Brain 145 (3), 1124-1138, 2022 | 54 | 2022 |
| Cloning, expression and characterization of human glutathione S-transferase Omega 2. L Wang, J Xu, C Ji, S Gu, Y Lv, S Li, Y Xu, Y Xie, Y Mao International journal of molecular medicine 16 (1), 19, 2005 | 49 | 2005 |
