Articles with public access mandates - William Nigel HunterLearn more
Available somewhere: 35
Heterogeneity in ess transcriptional organization and variable contribution of the Ess/Type VII protein secretion system to virulence across closely related S taphylocccus …
H Kneuper, ZP Cao, KB Twomey, M Zoltner, F Jäger, JS Cargill, ...
Molecular microbiology 93 (5), 928-943, 2014
Mandates: Science Foundation Ireland, UK Biotechnology and Biological Sciences …
Structure-based design and synthesis of antiparasitic pyrrolopyrimidines targeting pteridine reductase 1
AI Khalaf, JK Huggan, CJ Suckling, CL Gibson, K Stewart, F Giordani, ...
Journal of Medicinal Chemistry 57 (15), 6479-6494, 2014
Mandates: UK Medical Research Council, Wellcome Trust
EssC: domain structures inform on the elusive translocation channel in the Type VII secretion system
M Zoltner, WMAV Ng, JJ Money, PK Fyfe, H Kneuper, T Palmer, ...
Biochemical Journal 473 (13), 1941-1952, 2016
Mandates: UK Biotechnology and Biological Sciences Research Council, UK Medical …
How the structure of the large subunit controls function in an oxygen-tolerant [NiFe]-hydrogenase
L Bowman, L Flanagan, PK Fyfe, A Parkin, WN Hunter, F Sargent
Biochemical Journal 458 (3), 449-458, 2014
Mandates: UK Biotechnology and Biological Sciences Research Council, UK Engineering …
Structural basis for type VI secreted peptidoglycan DL-endopeptidase function, specificity and neutralization in Serratia marcescens
V Srikannathasan, G English, NK Bui, K Trunk, PEF O'Rourke, VA Rao, ...
Acta Crystallographica Section D: Biological Crystallography 69 (12), 2468-2482, 2013
Mandates: UK Biotechnology and Biological Sciences Research Council, UK Medical …
Membrane interactions and self‐association of components of the Ess/Type VII secretion system of Staphylococcus aureus
F Jäger, M Zoltner, H Kneuper, WN Hunter, T Palmer
FEBS letters 590 (3), 349-357, 2016
Mandates: UK Biotechnology and Biological Sciences Research Council, UK Medical …
Crystal structures of IspF from Plasmodium falciparum and Burkholderia cenocepacia: comparisons inform antimicrobial drug target assessment
PEF O’Rourke, J Kalinowska-Tłuścik, PK Fyfe, A Dawson, WN Hunter
BMC Structural Biology 14, 1-12, 2014
Mandates: UK Biotechnology and Biological Sciences Research Council, Wellcome Trust
Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery
P Linciano, A Dawson, I Pöhner, DM Costa, MS Sá, A Cordeiro-da-Silva, ...
ACS omega 2 (9), 5666-5683, 2017
Mandates: Wellcome Trust, Government of Italy
The structure of a Trypanosoma cruzi glucose‐6‐phosphate dehydrogenase reveals differences from the mammalian enzyme
GF Mercaldi, A Dawson, WN Hunter, AT Cordeiro
FEBS letters 590 (16), 2776-2786, 2016
Mandates: Wellcome Trust
Duration of androgen deprivation therapy with postoperative radiotherapy for prostate cancer: a comparison of long-course versus short-course androgen deprivation therapy in …
CC Parker, H Kynaston, AD Cook, NW Clarke, CN Catton, WR Cross, ...
The Lancet 403 (10442), 2416-2425, 2024
Mandates: Cancer Research UK, UK Medical Research Council, National Institute for …
The architecture of EssB, an integral membrane component of the type VII secretion system
M Zoltner, DG Norman, PK Fyfe, H El Mkami, T Palmer, WN Hunter
Structure 21 (4), 595-603, 2013
Mandates: UK Biotechnology and Biological Sciences Research Council, UK Medical …
Mutations in POGLUT1 in Galli–Galli/Dowling–Degos disease
NJ Wilson, C Cole, K Kroboth, WN Hunter, JA Mann, WHI McLean, ...
British journal of dermatology 176 (1), 270-274, 2017
Mandates: UK Medical Research Council, Wellcome Trust
Structure and activity of ChiX: a peptidoglycan hydrolase required for chitinase secretion by Serratia marcescens
RA Owen, PK Fyfe, A Lodge, J Biboy, W Vollmer, WN Hunter, F Sargent
Biochemical Journal 475 (2), 415-428, 2018
Mandates: UK Biotechnology and Biological Sciences Research Council, UK Medical …
Adding 6 months of androgen deprivation therapy to postoperative radiotherapy for prostate cancer: a comparison of short-course versus no androgen deprivation therapy in the …
CC Parker, NW Clarke, AD Cook, H Kynaston, CN Catton, WR Cross, ...
The Lancet 403 (10442), 2405-2415, 2024
Mandates: Cancer Research UK, UK Medical Research Council, National Institute for …
Characterization of 2,4-Diamino-6-oxo-1,6-dihydropyrimidin-5-yl Ureido Based Inhibitors of Trypanosoma brucei FolD and Testing for Antiparasitic Activity
TC Eadsforth, A Pinto, R Luciani, L Tamborini, G Cullia, C De Micheli, ...
Journal of medicinal chemistry 58 (20), 7938-7948, 2015
Mandates: Wellcome Trust, Government of Italy
High-resolution structure of the M14-type cytosolic carboxypeptidase from Burkholderia cenocepacia refined exploiting PDB_REDO strategies
V Rimsa, TC Eadsforth, RP Joosten, WN Hunter
Acta Crystallographica Section D: Biological Crystallography 70 (2), 279-289, 2014
Mandates: UK Biotechnology and Biological Sciences Research Council, Wellcome Trust
Two high-resolution structures of the human E3 ubiquitin ligase Siah1
V Rimsa, TC Eadsforth, WN Hunter
Acta Crystallographica Section F: Structural Biology and Crystallization …, 2013
Mandates: UK Biotechnology and Biological Sciences Research Council, Wellcome Trust
Engineering a surrogate human heteromeric α/β glycine receptor orthosteric site exploiting the structural homology and stability of acetylcholine-binding protein
A Dawson, P Trumper, JO de Souza, H Parker, MJ Jones, TG Hales, ...
IUCrJ 6 (6), 1014-1023, 2019
Mandates: Wellcome Trust
Structures of bacterial kynurenine formamidase reveal a crowded binuclear zinc catalytic site primed to generate a potent nucleophile
L Díaz-Sáez, V Srikannathasan, M Zoltner, WN Hunter
Biochemical Journal 462 (3), 581-589, 2014
Mandates: Wellcome Trust
Rhs NADase effectors and their immunity proteins are exchangeable mediators of inter-bacterial competition in Serratia
M Hagan, G Pankov, R Gallegos-Monterrosa, DJ Williams, C Earl, ...
Nature Communications 14 (1), 6061, 2023
Mandates: UK Medical Research Council, Wellcome Trust
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