| SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells R Hamamoto, Y Furukawa, M Morita, Y Iimura, FP Silva, M Li, R Yagyu, ... Nature cell biology 6 (8), 731-740, 2004 | 950 | 2004 |
| Overexpression of LSD1 contributes to human carcinogenesis through chromatin regulation in various cancers S Hayami, JD Kelly, HS Cho, M Yoshimatsu, M Unoki, T Tsunoda, HI Field, ... International journal of cancer 128 (3), 574-586, 2011 | 575 | 2011 |
| Enhanced SMYD3 expression is essential for the growth of breast cancer cells R Hamamoto, FP Silva, M Tsuge, T Nishidate, T Katagiri, Y Nakamura, ... Cancer science 97 (2), 113-118, 2006 | 408 | 2006 |
| Critical roles of non-histone protein lysine methylation in human tumorigenesis R Hamamoto, V Saloura, Y Nakamura Nature Reviews Cancer 15 (2), 110-124, 2015 | 399 | 2015 |
| Dysregulation of PRMT1 and PRMT6, Type I arginine methyltransferases, is involved in various types of human cancers M Yoshimatsu, G Toyokawa, S Hayami, M Unoki, T Tsunoda, HI Field, ... International journal of cancer 128 (3), 562-573, 2011 | 371 | 2011 |
| Development of a real-time endoscopic image diagnosis support system using deep learning technology in colonoscopy M Yamada, Y Saito, H Imaoka, M Saiko, S Yamada, H Kondo, ... Scientific reports 9 (1), 14465, 2019 | 265 | 2019 |
| Demethylation of RB regulator MYPT1 by histone demethylase LSD1 promotes cell cycle progression in cancer cells HS Cho, T Suzuki, N Dohmae, S Hayami, M Unoki, M Yoshimatsu, ... Cancer research 71 (3), 655-660, 2011 | 251 | 2011 |
| The development of a skin cancer classification system for pigmented skin lesions using deep learning S Jinnai, N Yamazaki, Y Hirano, Y Sugawara, Y Ohe, R Hamamoto Biomolecules 10 (8), 1123, 2020 | 242 | 2020 |
| Overexpression of the JmjC histone demethylase KDM5B in human carcinogenesis: involvement in the proliferation of cancer cells through the E2F/RB pathway S Hayami, M Yoshimatsu, A Veerakumarasivam, M Unoki, Y Iwai, ... Molecular cancer 9, 1-14, 2010 | 242 | 2010 |
| Recognition of modification status on a histone H3 tail by linked histone reader modules of the epigenetic regulator UHRF1 K Arita, S Isogai, T Oda, M Unoki, K Sugita, N Sekiyama, K Kuwata, ... Proceedings of the National Academy of Sciences 109 (32), 12950-12955, 2012 | 234 | 2012 |
| Validation of the histone methyltransferase EZH2 as a therapeutic target for various types of human cancer and as a prognostic marker M Takawa, K Masuda, M Kunizaki, Y Daigo, K Takagi, Y Iwai, HS Cho, ... Cancer science 102 (7), 1298-1305, 2011 | 221 | 2011 |
| RB1 methylation by SMYD2 enhances cell cycle progression through an increase of RB1 phosphorylation HS Cho, S Hayami, G Toyokawa, K Maejima, Y Yamane, T Suzuki, ... Neoplasia 14 (6), 476-IN8, 2012 | 220 | 2012 |
| Histone lysine methyltransferase SETD8 promotes carcinogenesis by deregulating PCNA expression M Takawa, HS Cho, S Hayami, G Toyokawa, M Kogure, Y Yamane, Y Iwai, ... Cancer research 72 (13), 3217-3227, 2012 | 213 | 2012 |
| The lysine 831 of vascular endothelial growth factor receptor 1 is a novel target of methylation by SMYD3 M Kunizaki, R Hamamoto, FP Silva, K Yamaguchi, T Nagayasu, ... Cancer research 67 (22), 10759-10765, 2007 | 203 | 2007 |
| Application of artificial intelligence technology in oncology: Towards the establishment of precision medicine R Hamamoto, K Suvarna, M Yamada, K Kobayashi, N Shinkai, M Miyake, ... Cancers 12 (12), 3532, 2020 | 199 | 2020 |
| Lysyl 5-hydroxylation, a novel histone modification, by Jumonji domain containing 6 (JMJD6) M Unoki, A Masuda, N Dohmae, K Arita, M Yoshimatsu, Y Iwai, Y Fukui, ... Journal of Biological Chemistry 288 (9), 6053-6062, 2013 | 149 | 2013 |
| UHRF1 is a novel diagnostic marker of lung cancer M Unoki, Y Daigo, J Koinuma, E Tsuchiya, R Hamamoto, Y Nakamura British journal of cancer 103 (2), 217-222, 2010 | 148 | 2010 |
| UHRF1 is a novel molecular marker for diagnosis and the prognosis of bladder cancer M Unoki, JD Kelly, DE Neal, BAJ Ponder, Y Nakamura, R Hamamoto British journal of cancer 101 (1), 98-105, 2009 | 147 | 2009 |
| A variable number of tandem repeats polymorphism in an E2F-1 binding element in the 5′ flanking region of SMYD3 is a risk factor for human cancers M Tsuge, R Hamamoto, FP Silva, Y Ohnishi, K Chayama, N Kamatani, ... Nature genetics 37 (10), 1104-1107, 2005 | 146 | 2005 |
| Enhanced expression of EHMT2 is involved in the proliferation of cancer cells through negative regulation of SIAH1 HS Cho, JD Kelly, S Hayami, G Toyokawa, M Takawa, M Yoshimatsu, ... Neoplasia 13 (8), 676-IN10, 2011 | 141 | 2011 |
Masaaki KomatsuRIKEN, NCCRI, JapanVerified email at ncc.go.jp