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Benjamin L. Oakes
Benjamin L. Oakes
Scribe Therapeutics
Verified email at berkeley.edu - Homepage
Title
Cited by
Cited by
Year
Programmable RNA recognition and cleavage by CRISPR/Cas9
MR O’Connell, BL Oakes, SH Sternberg, A East-Seletsky, M Kaplan, ...
Nature 516 (7530), 263-266, 2014
7882014
CasX enzymes comprise a distinct family of RNA-guided genome editors
JJ Liu, N Orlova, BL Oakes, E Ma, HB Spinner, KLM Baney, J Chuck, ...
Nature 566 (7743), 218-223, 2019
4652019
Circularly permuted and PAM-modified Cas9 variants broaden the targeting scope of base editors
TP Huang, KT Zhao, SM Miller, NM Gaudelli, BL Oakes, C Fellmann, ...
Nature biotechnology 37 (6), 626-631, 2019
2772019
Profiling of engineering hotspots identifies an allosteric CRISPR-Cas9 switch
BL Oakes, DC Nadler, A Flamholz, C Fellmann, BT Staahl, JA Doudna, ...
Nature biotechnology 34 (6), 646-651, 2016
2272016
Synthetic gene expression perturbation systems with rapid, tunable, single-gene specificity in yeast
RS McIsaac, BL Oakes, X Wang, KA Dummit, D Botstein, MB Noyes
Nucleic acids research 41 (4), e57-e57, 2013
1912013
Controlling CRISPR-Cas9 with ligand-activated and ligand-deactivated sgRNAs
K Kundert, JE Lucas, KE Watters, C Fellmann, AH Ng, BM Heineike, ...
Nature communications 10 (1), 2127, 2019
1882019
A systematic survey of the Cys2His2 zinc finger DNA-binding landscape
AV Persikov, JL Wetzel, EF Rowland, BL Oakes, DJ Xu, M Singh, ...
Nucleic acids research 43 (3), 1965-1984, 2015
1292015
CRISPR-Cas9 circular permutants as programmable scaffolds for genome modification
BL Oakes, C Fellmann, H Rishi, KL Taylor, SM Ren, DC Nadler, R Yokoo, ...
Cell 176 (1), 254-267. e16, 2019
1202019
Real-time optogenetic control of intracellular protein concentration in microbial cell cultures
J Melendez, M Patel, BL Oakes, P Xu, P Morton, MN McClean
Integrative Biology 6 (3), 366-372, 2014
832014
A yeast optogenetic toolkit (yOTK) for gene expression control in Saccharomyces cerevisiae
J An‐adirekkun, CJ Stewart, SH Geller, MT Patel, J Melendez, BL Oakes, ...
Biotechnology and bioengineering 117 (3), 886-893, 2020
492020
Deep sequencing of large library selections allows computational discovery of diverse sets of zinc fingers that bind common targets
AV Persikov, EF Rowland, BL Oakes, M Singh, MB Noyes
Nucleic acids research 42 (3), 1497-1508, 2014
492014
Comprehensive deletion landscape of CRISPR-Cas9 identifies minimal RNA-guided DNA-binding modules
A Shams, SA Higgins, C Fellmann, TG Laughlin, BL Oakes, R Lew, S Kim, ...
Nature Communications 12 (1), 5664, 2021
432021
Protein Engineering of Cas9 for Enhanced Function.
BL Oakes, DC Nadler, DF Savage
Methods in enzymology 546, 491-511, 2014
362014
Copper modulates the phenotypic response of activated BV2 microglia through the release of nitric oxide
A Rossi-George, CJ Guo, BL Oakes, AJ Gow
Nitric Oxide 27 (4), 201-209, 2012
322012
Multi-reporter selection for the design of active and more specific zinc-finger nucleases for genome editing
BL Oakes, DF Xia, EF Rowland, DJ Xu, I Ankoudinova, JS Borchardt, ...
Nature Communications 7 (1), 10194, 2016
252016
Methods and compositions for modifying a single stranded target nucleic acid
JA Doudna, SH Sternberg, M O'connell, B Oakes
US Patent 9,994,831, 2018
232018
New approaches for targeting PCSK9: small-interfering ribonucleic acid and genome editing
RF Oostveen, AV Khera, S Kathiresan, ESG Stroes, K Fitzgerald, ...
Arteriosclerosis, thrombosis, and vascular biology 43 (7), 1081-1092, 2023
172023
CRISPR-CasX is an RNA-dominated enzyme active for human genome editing
JJ Liu, N Orlova, BL Oakes, E Ma, HB Spinner, KLM Baney, J Chuck, ...
Nature 566 (7743), 218, 2019
132019
Rapid synthesis and screening of chemically activated transcription factors with GFP-based reporters
RS McIsaac, BL Oakes, D Botstein, MB Noyes
JoVE (Journal of Visualized Experiments), e51153-e51153, 2013
102013
Variant type v crispr/cas effector polypeptides and methods of use thereof
JA Doudna, BL Oakes, N Orlova, J Liu
US Patent App. 17/266,270, 2021
62021
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