Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease M Wernig, JP Zhao, J Pruszak, E Hedlund, D Fu, F Soldner, V Broccoli, ... Proceedings of the National Academy of Sciences 105 (15), 5856-5861, 2008 | 1713 | 2008 |
Direct generation of functional dopaminergic neurons from mouse and human fibroblasts M Caiazzo, MT Dell’Anno, E Dvoretskova, D Lazarevic, S Taverna, D Leo, ... Nature 476 (7359), 224-227, 2011 | 1261 | 2011 |
Mapping Wnt/β-catenin signaling during mouse development and in colorectal tumors S Maretto, M Cordenonsi, S Dupont, P Braghetta, V Broccoli, AB Hassan, ... Proceedings of the National Academy of Sciences 100 (6), 3299-3304, 2003 | 932 | 2003 |
The meso-angioblast: a multipotent, self-renewing cell that originates from the dorsal aorta and differentiates into most mesodermal tissues MG Minasi, M Riminucci, L De Angelis, U Borello, B Berarducci, ... Oxford University Press for The Company of Biologists Limited 129 (11), 2773 …, 2002 | 620 | 2002 |
FOXG1 is responsible for the congenital variant of Rett syndrome F Ariani, G Hayek, D Rondinella, R Artuso, MA Mencarelli, ... The American Journal of Human Genetics 83 (1), 89-93, 2008 | 535 | 2008 |
Tbr2 directs conversion of radial glia into basal precursors and guides neuronal amplification by indirect neurogenesis in the developing neocortex A Sessa, C Mao, AK Hadjantonakis, WH Klein, V Broccoli Neuron 60 (1), 56-69, 2008 | 439 | 2008 |
CDKL5 belongs to the same molecular pathway of MeCP2 and it is responsible for the early-onset seizure variant of Rett syndrome F Mari, S Azimonti, I Bertani, F Bolognese, E Colombo, R Caselli, E Scala, ... Human molecular genetics 14 (14), 1935-1946, 2005 | 406 | 2005 |
Site-specific integration and tailoring of cassette design for sustainable gene transfer A Lombardo, D Cesana, P Genovese, B Di Stefano, E Provasi, ... Nature methods 8 (10), 861-869, 2011 | 404 | 2011 |
Axonal degeneration in paraplegin-deficient mice is associated with abnormal mitochondria and impairment of axonal transport F Ferreirinha, A Quattrini, M Pirozzi, V Valsecchi, G Dina, V Broccoli, ... The Journal of clinical investigation 113 (2), 231-242, 2004 | 384 | 2004 |
The caudal limit of Otx2 expression positions the isthmic organizer V Broccoli, E Boncinelli, W Wurst Nature 401 (6749), 164-168, 1999 | 372 | 1999 |
Transplantation of genetically corrected human iPSC-derived progenitors in mice with limb-girdle muscular dystrophy FS Tedesco, MFM Gerli, L Perani, S Benedetti, F Ungaro, M Cassano, ... Science translational medicine 4 (140), 140ra89-140ra89, 2012 | 328 | 2012 |
The simultaneous loss of Arx and Pax4 genes promotes a somatostatin-producing cell fate specification at the expense of the α-and β-cell lineages in the mouse … P Collombat, J Hecksher-Sørensen, V Broccoli, J Krull, I Ponte, ... Oxford University Press for The Company of Biologists Limited 132 (13), 2969 …, 2005 | 308 | 2005 |
CDKL5 ensures excitatory synapse stability by reinforcing NGL-1–PSD95 interaction in the postsynaptic compartment and is impaired in patient iPSC-derived neurons S Ricciardi, F Ungaro, M Hambrock, N Rademacher, G Stefanelli, ... Nature cell biology 14 (9), 911-923, 2012 | 299 | 2012 |
Defective neurogenesis in citron kinase knockout mice by altered cytokinesis and massive apoptosis F Di Cunto, S Imarisio, E Hirsch, V Broccoli, A Bulfone, A Migheli, C Atzori, ... Neuron 28 (1), 115-127, 2000 | 287 | 2000 |
Emx1 and Emx2 Show Different Patterns of Expression During Proliferation and Differentiation of the Developing Cerebral Cortex in the Mouse M Gulisano, V Broccoli, C Pardini, E Boncinelli European Journal of Neuroscience 8 (5), 1037-1050, 1996 | 279 | 1996 |
Reduced AKT/mTOR signaling and protein synthesis dysregulation in a Rett syndrome animal model S Ricciardi, EM Boggio, S Grosso, G Lonetti, G Forlani, G Stefanelli, ... Human molecular genetics 20 (6), 1182-1196, 2011 | 264 | 2011 |
Direct conversion of fibroblasts into functional astrocytes by defined transcription factors M Caiazzo, S Giannelli, P Valente, G Lignani, A Carissimo, A Sessa, ... Stem cell reports 4 (1), 25-36, 2015 | 259 | 2015 |
Importance of Shank3 protein in regulating metabotropic glutamate receptor 5 (mGluR5) expression and signaling at synapses C Verpelli, E Dvoretskova, C Vicidomini, F Rossi, M Chiappalone, ... Journal of Biological Chemistry 286 (40), 34839-34850, 2011 | 239 | 2011 |
CDKL5 expression is modulated during neuronal development and its subcellular distribution is tightly regulated by the C-terminal tail L Rusconi, L Salvatoni, L Giudici, I Bertani, C Kilstrup-Nielsen, V Broccoli, ... Journal of Biological Chemistry 283 (44), 30101-30111, 2008 | 225 | 2008 |
c-otx2 is expressed in two different phases of gastrulation and is sensitive to retinoic acid treatment in chick embryo L Bally-Cuif, M Gulisano, V Broccoli, E Boncinelli Mechanisms of development 49 (1-2), 49-63, 1995 | 225 | 1995 |