Adnan Sljoka

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Robert Scott ProsserChemistry, Biochemistry, University of TorontoVerified email at utoronto.ca
Walter WhiteleyYork University, TorontoVerified email at mathstat.yorku.ca
Roger SunaharaUniversity of California San DiegoVerified email at ucsd.edu
Derek James WilsonChemsitry, York UniversityVerified email at yorku.ca
Libin YeAssociate Professor at University of South Florida and H. Lee Moffitt Cancer CenterVerified email at usf.edu
Shuya Kate HuangUniversity of TorontoVerified email at mail.utoronto.ca
Aditya Pandey, Ph.D.Scientist, IBEX Pharmaceutical Inc.Verified email at utoronto.ca
Bernd SchulzeLancaster UniversityVerified email at lancaster.ac.uk
Christopher IngUniversity of TorontoVerified email at mail.utoronto.ca
Tae Hun KimAssistant Professor, Department of Biochemistry, Case Western Reserve UniversityVerified email at case.edu
Angel E GarciaCenter for Non Linear Studies, Los Alamos National LaboratoryVerified email at lanl.gov
Chris NealeSoftware Developer, OpenEye Cadence Molecular SciencesVerified email at eyesopen.com
Gerald F. AudetteYork UniversityVerified email at yorku.ca
Michael P WilliamsonProfessor of Biochemistry, University of SheffieldVerified email at sheffield.ac.uk
Daisuke KurodaNational Institute of Infectious DiseasesVerified email at niid.go.jp
Jeffrey J. GrayJohns Hopkins University, Chemical and Biomolecular Engineering / Program in Molecular BiophysicsVerified email at jhu.edu
Jeliazko R. JeliazkovGlaxoSmithKlineVerified email at gsk.com
Tony NixonLancaster UniversityVerified email at lancaster.ac.uk
Josep M PortaInstitut de Robòtica i Informàtica Industrial, CSIC-UPCVerified email at iri.upc.edu
Lluís RosInstitut de Robòtica i Informàtica Industrial, CSIC-UPCVerified email at iri.upc.edu

Adnan Sljoka

University of Toronto

Verified email at utoronto.ca - Homepage

Rigidity Theory Algorithms Machine Learning Protein dynamics Allostery and drug discovery


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The role of dimer asymmetry and protomer dynamics in enzyme catalysis TH Kim, P Mehrabi, Z Ren, A Sljoka, C Ing, A Bezginov, L Ye, R Pomès, ... Science 355 (6322), eaag2355, 2017	176	2017
Mechanistic insights into allosteric regulation of the A_2A adenosine G protein-coupled receptor by physiological cations L Ye, C Neale, A Sljoka, B Lyda, D Pichugin, N Tsuchimura, ST Larda, ... Nature communications 9 (1), 1372, 2018	174	2018
Delineating the conformational landscape of the adenosine A2A receptor during G protein coupling SK Huang, A Pandey, DP Tran, NL Villanueva, A Kitao, RK Sunahara, ... Cell 184 (7), 1884-1894. e14, 2021	127	2021
Hyperphosphorylation of intrinsically disordered tau protein induces an amyloidogenic shift in its conformational ensemble S Zhu, A Shala, A Bezginov, A Sljoka, G Audette, DJ Wilson PLoS One 10 (3), e0120416, 2015	109	2015
Repertoire analysis of antibody CDR-H3 loops suggests affinity maturation does not typically result in rigidification JR Jeliazkov, A Sljoka, D Kuroda, N Tsuchimura, N Katoh, K Tsumoto, ... Frontiers in immunology 9, 413, 2018	62	2018
A method for validating the accuracy of NMR protein structures NJ Fowler, A Sljoka, MP Williamson Nature Communications 11 (1), 6321, 2020	55	2020
Allosteric modulation of the adenosine A2A receptor by cholesterol SK Huang, O Almurad, RJ Pejana, ZA Morrison, A Pandey, LP Picard, ... Elife 11, e73901, 2022	44	2022
Substrate-based allosteric regulation of a homodimeric enzyme P Mehrabi, C Di Pietrantonio, TH Kim, A Sljoka, K Taverner, C Ing, ... Journal of the American Chemical Society 141 (29), 11540-11556, 2019	38	2019
Checking mobility and decomposition of linkages via pebble game algorithm A Sljoka, O Shai, W Whiteley International Design Engineering Technical Conferences and Computers and …, 2011	35	2011
How does symmetry impact the flexibility of proteins? B Schulze, A Sljoka, W Whiteley Philosophical Transactions of the Royal Society A: Mathematical, Physical …, 2014	34	2014
Suppressing allostery in epitope mapping experiments using millisecond hydrogen/deuterium exchange mass spectrometry B Deng, S Zhu, AM Macklin, J Xu, C Lento, A Sljoka, DJ Wilson MAbs 9 (8), 1327-1336, 2017	31	2017
Probing protein ensemble rigidity and hydrogen–deuterium exchange A Sljoka, D Wilson Physical biology 10 (5), 056013, 2013	29	2013
Directed graphs, decompositions, and spatial linkages O Shai, A Sljoka, W Whiteley Discrete Applied Mathematics 161 (18), 3028-3047, 2013	28	2013
Algorithms in rigidity theory with applications to protein flexibility and mechanical linkages A Sljoka York University, 2012	28	2012
Counting for rigidity, flexibility and extensions via the pebble game algorithm A Sljoka York University, 2006	17	2006
Mapping the conformational landscape of the stimulatory heterotrimeric G protein SK Huang, LP Picard, RSM Rahmatullah, A Pandey, N Van Eps, ... Nature Structural & Molecular Biology 30 (4), 502-511, 2023	15	2023
Probing allosteric mechanism with long-range rigidity transmission across protein networks A Sljoka Allostery: Methods and Protocols, 61-75, 2021	15	2021
Feedforward control of plant nitrate transporter NRT1. 1 biphasic adaptive activity M Rashid, S Bera, M Banerjee, AB Medvinsky, GQ Sun, BL Li, A Sljoka, ... Biophysical Journal 118 (4), 898-908, 2020	15	2020
Low pH structure of heliorhodopsin reveals chloride binding site and intramolecular signaling pathway JE Besaw, J Reichenwallner, P De Guzman, A Tucs, A Kuo, T Morizumi, ... Scientific reports 12 (1), 13955, 2022	13	2022
Structural and functional analysis of proteins using rigidity theory A Sljoka Sublinear Computation Paradigm: Algorithmic Revolution in the Big Data Era …, 2022	13	2022

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