| mTOR inhibition alleviates mitochondrial disease in a mouse model of Leigh syndrome SC Johnson, ME Yanos, EB Kayser, A Quintana, M Sangesland, ... Science 342 (6165), 1524-1528, 2013 | 550 | 2013 |
| A comprehensive analysis of replicative lifespan in 4,698 single-gene deletion strains uncovers conserved mechanisms of aging MA McCormick, JR Delaney, M Tsuchiya, S Tsuchiyama, A Shemorry, ... Cell metabolism 22 (5), 895-906, 2015 | 268 | 2015 |
| Molecular mechanisms underlying genotype‐dependent responses to dietary restriction J Schleit, SC Johnson, CF Bennett, M Simko, N Trongtham, A Castanza, ... Aging cell 12 (6), 1050-1061, 2013 | 180 | 2013 |
| Extending support for mouse data in the Molecular Signatures Database (MSigDB) AS Castanza, JM Recla, D Eby, H Thorvaldsdóttir, CJ Bult, JP Mesirov Nature methods 20 (11), 1619-1620, 2023 | 130 | 2023 |
| Dose-dependent effects of mTOR inhibition on weight and mitochondrial disease in mice SC Johnson, ME Yanos, A Bitto, A Castanza, A Gagnidze, B Gonzalez, ... Frontiers in genetics 6, 247, 2015 | 101 | 2015 |
| pH neutralization protects against reduction in replicative lifespan following chronological aging in yeast C Murakami, JR Delaney, A Chou, D Carr, J Schleit, GL Sutphin, EH An, ... Cell cycle 11 (16), 3087-3096, 2012 | 80 | 2012 |
| Stress profiling of longevity mutants identifies Afg3 as a mitochondrial determinant of cytoplasmic mRNA translation and aging JR Delaney, U Ahmed, A Chou, S Sim, D Carr, CJ Murakami, J Schleit, ... Aging cell 12 (1), 156-166, 2013 | 77 | 2013 |
| Dietary restriction and mitochondrial function link replicative and chronological aging in Saccharomyces cerevisiae JR Delaney, C Murakami, A Chou, D Carr, J Schleit, GL Sutphin, EH An, ... Experimental gerontology 48 (10), 1006-1013, 2013 | 66 | 2013 |
| PTEN deficiency leads to proteasome addiction: a novel vulnerability in glioblastoma JA Benitez, D Finlay, A Castanza, AD Parisian, J Ma, C Longobardi, ... Neuro-Oncology 23 (7), 1072-1086, 2021 | 38 | 2021 |
| End-of-life cell cycle arrest contributes to stochasticity of yeast replicative aging JR Delaney, A Chou, B Olsen, D Carr, C Murakami, U Ahmed, S Sim, ... FEMS yeast research 13 (3), 267-276, 2013 | 37 | 2013 |
| AUTS2 syndrome: molecular mechanisms and model systems A Biel, AS Castanza, R Rutherford, SR Fair, L Chifamba, JC Wester, ... Frontiers in molecular neuroscience 15, 858582, 2022 | 31 | 2022 |
| AUTS2 regulates RNA metabolism and dentate gyrus development in mice AS Castanza, S Ramirez, PP Tripathi, RAM Daza, FK Kalume, ... Cerebral Cortex 31 (10), 4808-4824, 2021 | 21 | 2021 |
| Dosedependent effects of mTOR inhibition on weight and mitochondrial disease in mice. Front Genet. 2015; 6: 247 SC Johnson, ME Yanos, A Bitto, A Castanza, A Gagnidze, B Gonzalez, ... | 12 | 2015 |
| Data driven refinement of gene expression signatures for enrichment analysis AT Wenzel, F Faraji, K Sato, K Medetgul-Ernar, A Castanza, R Sagatelian, ... bioRxiv, 2024.11. 03.621768, 2024 | | 2024 |
| Extended support for model organisms: The next frontier for the molecular signatures database AS Castanza, JM Recla, D Eby, AT Wenzel, H Thorvaldsdottir, CJ Bult, ... Cancer Research 83 (7_Supplement), 6568-6568, 2023 | | 2023 |
| The Molecular Signatures Database Revisited: Extending Support for Mouse Data AS Castanza, JM Recla, D Eby, H Thorvaldsdóttir, CJ Bult, JP Mesirov bioRxiv, 2022.10. 24.513539, 2022 | | 2022 |
| Molecular and Cellular Phenotypes of AUTS2 Deficiency in the Developing Mouse Cortex and Hippocampus AS Castanza | | 2018 |
| AFFECTS AND MECHANISM OF RAPAMYCIN AS AN INTERVENTION IN THE MOUSE MODEL FOR THE HUMAN MITOCHONDRIAL DISEASE LEIGH SYNDROME SC Johnson, AS Castanza, M Kaeberlein GERONTOLOGIST 52, 578-579, 2012 | | 2012 |
| Defective Autophagy Plays a Role in the Development of Angiotensin-Induced Cardiac Hypertrophy SC Johnson, V Nguyen, A Castanza, PS Rabinovitch Circulation Research 111 (suppl_1), A263-A263, 2012 | | 2012 |
