Chemical and biological approaches synergize to ameliorate protein-folding diseases TW Mu, DST Ong, YJ Wang, WE Balch, JR Yates, L Segatori, JW Kelly Cell 134 (5), 769-781, 2008 | 439 | 2008 |
Partial restoration of mutant enzyme homeostasis in three distinct lysosomal storage disease cell lines by altering calcium homeostasis TW Mu, DM Fowler, JW Kelly PLoS biology 6 (2), e26, 2008 | 148 | 2008 |
Endoplasmic reticulum Ca2+ increases enhance mutant glucocerebrosidase proteostasis DST Ong, TW Mu, AE Palmer, JW Kelly Nature chemical biology 6 (6), 424-432, 2010 | 116 | 2010 |
Different binding orientations for the same agonist at homologous receptors: a lock and key or a simple wedge? TW Mu, HA Lester, DA Dougherty Journal of the American Chemical Society 125 (23), 6850-6851, 2003 | 95 | 2003 |
The performance of the Benesi-Hildebrand method in measuring the binding constants of the cyclodextrin complexation C Yang, L Liu, TW Mu, QX Guo Analytical sciences 16 (5), 537-539, 2000 | 94 | 2000 |
A systematic quantum chemistry study on cyclodextrins XS Li, L Liu, TW Mu, QX Guo Monatshefte fuer Chemie/Chemical Monthly 131, 849-855, 2000 | 90 | 2000 |
Using pharmacological chaperones to restore proteostasis YJ Wang, XJ Di, TW Mu Pharmacological research 83, 3-9, 2014 | 63 | 2014 |
SAHA enhances proteostasis of epilepsy-associated α1 (A322D) β2γ2 GABAA receptors XJ Di, DY Han, YJ Wang, MR Chance, TW Mu Chemistry & biology 20 (12), 1456-1468, 2013 | 54 | 2013 |
Grp94 protein delivers γ-aminobutyric acid type A (GABAA) receptors to Hrd1 protein-mediated endoplasmic reticulum-associated degradation XJ Di, YJ Wang, DY Han, YL Fu, AS Duerfeldt, BSJ Blagg, TW Mu Journal of Biological Chemistry 291 (18), 9526-9539, 2016 | 50 | 2016 |
GADD34 function in protein trafficking promotes adaptation to hyperosmotic stress in human corneal cells D Krokowski, BJ Guan, J Wu, Y Zheng, PP Pattabiraman, R Jobava, ... Cell reports 21 (10), 2895-2910, 2017 | 41 | 2017 |
LMAN1 (ERGIC-53) promotes trafficking of neuroreceptors YL Fu, B Zhang, TW Mu Biochemical and biophysical research communications 511 (2), 356-362, 2019 | 37 | 2019 |
Methods for treating a condition characterized by dysfunction in protein homeostasis L Segatori, TW Mu, JW Kelly US Patent App. 12/364,441, 2009 | 35 | 2009 |
L-type Calcium Channel Blockers Enhance Trafficking and Function of Epilepsy-associated α1(D219N) Subunits of GABAA Receptors DY Han, BJ Guan, YJ Wang, M Hatzoglou, TW Mu ACS chemical biology 10 (9), 2135-2148, 2015 | 34 | 2015 |
Combining valosin-containing protein (VCP) inhibition and suberanilohydroxamic acid (SAHA) treatment additively enhances the folding, trafficking, and function of epilepsy … DY Han, XJ Di, YL Fu, TW Mu Journal of Biological Chemistry 290 (1), 325-337, 2015 | 33 | 2015 |
Interplay between molecular recognition and redox properties: a theoretical study of the inclusion complexation of β-cyclodextrin with phenothiazine and its radical cation L Liu, XS Li, TW Mu, QX Guo, YC Liu Journal of inclusion phenomena and macrocyclic chemistry 38, 199-206, 2000 | 28 | 2000 |
FKBP10 depletion enhances glucocerebrosidase proteostasis in Gaucher disease fibroblasts DST Ong, YJ Wang, YL Tan, JR Yates, TW Mu, JW Kelly Chemistry & biology 20 (3), 403-415, 2013 | 26 | 2013 |
Remodeling the endoplasmic reticulum proteostasis network restores proteostasis of pathogenic GABAA receptors YL Fu, DY Han, YJ Wang, XJ Di, HB Yu, TW Mu PloS one 13 (11), e0207948, 2018 | 25 | 2018 |
Ab initio calculations on the inclusion complexation of cyclobis (paraquat-p-phenylene) KC Zhang, L Liu, TW Mu, QX Guo Chemical Physics Letters 333 (1-2), 195-198, 2001 | 24 | 2001 |
Proteostasis maintenance of Cys-loop receptors YL Fu, YJ Wang, TW Mu Advances in protein chemistry and structural biology 103, 1-23, 2016 | 22 | 2016 |
A theoretical study on the inclusion complexation of cyclodextrins with radical cations and anions TW Mu, L Liu, XS Li, QX Guo Journal of Physical Organic Chemistry 14 (8), 559-565, 2001 | 22 | 2001 |