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Aleem Syed
Aleem Syed
Dana-Farber Cancer Institute/Harvard Medical School
Verified email at dfci.harvard.edu
Title
Cited by
Cited by
Year
The MRE11–RAD50–NBS1 complex conducts the orchestration of damage signaling and outcomes to stress in DNA replication and repair
A Syed, JA Tainer
Annual Review of Biochemistry 87 (1), 263-294, 2018
4272018
BODIPY-derived photoremovable protecting groups unmasked with green light
PP Goswami, A Syed, CL Beck, TR Albright, KM Mahoney, R Unash, ...
Journal of the American Chemical Society 137 (11), 3783-3786, 2015
2972015
A first-in-class polymerase theta inhibitor selectively targets homologous-recombination-deficient tumors
J Zhou, C Gelot, C Pantelidou, A Li, H Yücel, RE Davis, A Färkkilä, ...
Nature Cancer 2 (6), 598-610, 2021
2812021
Family of BODIPY photocages cleaved by single photons of visible/near-infrared light
JA Peterson, C Wijesooriya, EJ Gehrmann, KM Mahoney, PP Goswami, ...
Journal of the American Chemical Society 140 (23), 7343-7346, 2018
2802018
Raman imaging in cell membranes, lipid-rich organelles, and lipid bilayers
A Syed, EA Smith
Annual Review of Analytical Chemistry 10 (1), 271-291, 2017
472017
GRB2 enforces homology-directed repair initiation by MRE11
Z Ye, S Xu, Y Shi, A Bacolla, A Syed, D Moiani, CL Tsai, Q Shen, G Peng, ...
Science Advances 7 (32), eabe9254, 2021
352021
Targeting allostery with avatars to design inhibitors assessed by cell activity: dissecting MRE11 endo-and exonuclease activities
D Moiani, DA Ronato, CA Brosey, AS Arvai, A Syed, JY Masson, E Petricci, ...
Methods in Enzymology 601, 205-241, 2018
272018
Novobiocin blocks nucleic acid binding to Polθ and inhibits stimulation of its ATPase activity
A Syed, F Filandr, J Patterson-Fortin, A Bacolla, R Ravindranathan, ...
Nucleic Acids Research 51 (18), 9920-9937, 2023
162023
Single particle tracking with sterol modulation reveals the cholesterol-mediated diffusion properties of integrin receptors
N Arora, A Syed, S Sander, EA Smith
Physical Biology 11 (6), 066001, 2014
142014
Dynamics of the DYNLL1–MRE11 complex regulate DNA end resection and recruitment of Shieldin to DSBs
ML Swift, R Zhou, A Syed, LA Moreau, B Tomasik, JA Tainer, ...
Nature Structural & Molecular Biology 30 (10), 1456-1467, 2023
132023
Ligand binding affinity and changes in the lateral diffusion of receptor for advanced glycation endproducts (RAGE)
A Syed, Q Zhu, EA Smith
Biochimica et Biophysica Acta (BBA)-Biomembranes 1858 (12), 3141-3149, 2016
122016
Combining small angle X-ray scattering (SAXS) with protein structure predictions to characterize conformations in solution
NB Chinnam, A Syed, GL Hura, M Hammel, JA Tainer, SE Tsutakawa
Methods in Enzymology 678, 351-376, 2023
112023
Automating data analysis for hydrogen/deuterium exchange mass spectrometry using data-independent acquisition methodology
F Filandr, V Sarpe, S Raval, DA Crowder, MF Khan, P Douglas, S Coales, ...
Nature Communications 15 (1), 2200, 2024
92024
Monitoring nuclease activity by x-ray scattering interferometry using gold nanoparticle-conjugated DNA
DJ Rosenberg, A Syed, JA Tainer, GL Hura
DNA Damage Responses: Methods and Protocols, 183-205, 2022
82022
The number of accumulated photons and the quality of stimulated emission depletion lifetime images
A Syed, MD Lesoine, U Bhattacharjee, JW Petrich, EA Smith
Photochemistry and Photobiology 90 (4), 767-772, 2014
82014
Charge transport communication through DNA by protein Fe–S clusters: How far is not too far?
A Syed, JA Tainer
ACS Central Science 5 (1), 7-9, 2019
72019
Self-immolative phthalate esters sensitive to hydrogen peroxide and light
KM Mahoney, PP Goswami, A Syed, P Kolker, B Shannan, EA Smith, ...
The Journal of Organic Chemistry 79 (23), 11740-11743, 2014
72014
Lateral diffusion and signaling of receptor for advanced glycation end-products (RAGE): a receptor involved in chronic inflammation
A Syed, Q Zhu, EA Smith
European Biophysics Journal 47, 39-48, 2018
52018
Role of insulin receptor and insulin signaling on αPS2CβPS integrins’ lateral diffusion
D Mainali, A Syed, N Arora, EA Smith
European Biophysics Journal 43, 603-611, 2014
42014
ASCC1 structures and bioinformatics reveal a novel helix-clasp-helix RNA-binding motif linked to a two-histidine phosphodiesterase
N babu Chinnam, R Thapar, AS Arvai, AH Sarker, JM Soll, T Paul, A Syed, ...
Journal of Biological Chemistry 300 (6), 2024
22024
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