A presenilin-1/γ-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions P Marambaud, J Shioi, G Serban, A Georgakopoulos, S Sarner, V Nagy, ... The EMBO journal 21 (8), 1948-1956, 2002 | 925 | 2002 |
PS1 activates PI3K thus inhibiting GSK‐3 activity and tau overphosphorylation: effects of FAD mutations L Baki, J Shioi, P Wen, Z Shao, A Schwarzman, M Gama‐Sosa, R Neve, ... The EMBO journal 23 (13), 2586-2596, 2004 | 372 | 2004 |
Decoding the signaling of a GPCR heteromeric complex reveals a unifying mechanism of action of antipsychotic drugs M Fribourg, JL Moreno, T Holloway, D Provasi, L Baki, R Mahajan, G Park, ... Cell 147 (5), 1011-1023, 2011 | 333 | 2011 |
Presenilin-1 binds cytoplasmic epithelial cadherin, inhibits cadherin/p120 association, and regulates stability and function of the cadherin/catenin adhesion complex L Baki, P Marambaud, S Efthimiopoulos, A Georgakopoulos, P Wen, ... Proceedings of the National Academy of Sciences 98 (5), 2381-2386, 2001 | 235 | 2001 |
Metalloproteinase/Presenilin1 processing of ephrinB regulates EphB‐induced Src phosphorylation and signaling A Georgakopoulos, C Litterst, E Ghersi, L Baki, CJ Xu, G Serban, ... The EMBO journal 25 (6), 1242-1252, 2006 | 219 | 2006 |
Allosteric signaling through an mGlu2 and 5-HT2A heteromeric receptor complex and its potential contribution to schizophrenia JL Moreno, P Miranda-Azpiazu, A García-Bea, J Younkin, M Cui, ... Science signaling 9 (410), ra5-ra5, 2016 | 124 | 2016 |
FAD mutants unable to increase neurotoxic Aβ 42 suggest that mutation effects on neurodegeneration may be independent of effects on Aβ J Shioi, A Georgakopoulos, P Mehta, Z Kouchi, CM Litterst, L Baki, ... Journal of neurochemistry 101 (3), 674-681, 2007 | 118 | 2007 |
Phosphatidylinositol-4, 5-bisphosphate regulates epidermal growth factor receptor activation IE Michailidis, R Rusinova, A Georgakopoulos, Y Chen, R Iyengar, ... Pflügers Archiv-European Journal of Physiology 461, 387-397, 2011 | 96 | 2011 |
Phosphoinositide control of membrane protein function: a frontier led by studies on ion channels DE Logothetis, VI Petrou, M Zhang, R Mahajan, XY Meng, SK Adney, ... Annual review of physiology 77 (1), 81-104, 2015 | 92 | 2015 |
Wild-type but not FAD mutant presenilin-1 prevents neuronal degeneration by promoting phosphatidylinositol 3-kinase neuroprotective signaling L Baki, RL Neve, Z Shao, J Shioi, A Georgakopoulos, NK Robakis Journal of Neuroscience 28 (2), 483-490, 2008 | 77 | 2008 |
Endothelin signalling regulates volume-sensitive Cl− current via NADPH oxidase and mitochondrial reactive oxygen species W Deng, L Baki, CM Baumgarten Cardiovascular research 88 (1), 93-100, 2010 | 60 | 2010 |
Cadherins mediate both the association between PS1 and β-catenin and the effects of PS1 on β-catenin stability G Serban, Z Kouchi, L Baki, A Georgakopoulos, CM Litterst, J Shioi, ... Journal of Biological Chemistry 280 (43), 36007-36012, 2005 | 59 | 2005 |
HIV protease inhibitors elicit volume-sensitive Cl− current in cardiac myocytes via mitochondrial ROS W Deng, L Baki, J Yin, H Zhou, CM Baumgarten Journal of molecular and cellular cardiology 49 (5), 746-752, 2010 | 52 | 2010 |
Gating of a G protein-sensitive mammalian Kir3. 1 prokaryotic Kir channel chimera in planar lipid bilayers E Leal-Pinto, Y Gomez-Llorente, S Sundaram, QY Tang, ... Journal of Biological Chemistry 285 (51), 39790-39800, 2010 | 47 | 2010 |
Cross-signaling in metabotropic glutamate 2 and serotonin 2A receptor heteromers in mammalian cells L Baki, M Fribourg, J Younkin, JM Eltit, JL Moreno, G Park, Z Vysotskaya, ... Pflügers Archiv-European Journal of Physiology 468, 775-793, 2016 | 39 | 2016 |
Cholesterol increases the open probability of cardiac KACh currents AN Bukiya, CV Osborn, G Kuntamallappanavar, PT Toth, L Baki, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1848 (10), 2406-2413, 2015 | 29 | 2015 |
Hydrogen sulfide inhibits Kir2 and Kir3 channels by decreasing sensitivity to the phospholipid phosphatidylinositol 4, 5-bisphosphate (PIP2) J Ha, Y Xu, T Kawano, T Hendon, L Baki, S Garai, A Papapetropoulos, ... Journal of Biological Chemistry 293 (10), 3546-3561, 2018 | 20 | 2018 |
Reformulating a Pharmacophore for 5-HT2A Serotonin Receptor Antagonists J Younkin, SA Gaitonde, A Ellaithy, R Vekariya, L Baki, JL Moreno, ... ACS chemical neuroscience 7 (9), 1292-1299, 2016 | 13 | 2016 |
Regulation of tyrosine aminotransferase gene expression by glucocorticoids in quiescent and regenerating liver L BAKI, MN Alexis Biochemical Journal 320 (3), 745-753, 1996 | 7 | 1996 |
The efficiency of nuclear processing of the tyrosine aminotransferase mRNA transcript increases after partial hepatectomy L Baki, MN Alexis European journal of biochemistry 225 (3), 797-803, 1994 | 6 | 1994 |