Functional specializations of intestinal dendritic cell and macrophage subsets that control Th17 and regulatory T cell responses are dependent on the T cell/APC ratio, source … TL Denning, BA Norris, O Medina-Contreras, S Manicassamy, D Geem, ... The Journal of Immunology 187 (2), 733-747, 2011 | 404 | 2011 |
CX3CR1 regulates intestinal macrophage homeostasis, bacterial translocation, and colitogenic Th17 responses in mice O Medina-Contreras, D Geem, O Laur, IR Williams, SA Lira, A Nusrat, ... The Journal of clinical investigation 121 (12), 4787-4795, 2011 | 354 | 2011 |
Fab'-bearing siRNA TNFα-loaded nanoparticles targeted to colonic macrophages offer an effective therapy for experimental colitis H Laroui, E Viennois, B Xiao, BSB Canup, D Geem, TL Denning, D Merlin Journal of Controlled Release 186, 41-53, 2014 | 161 | 2014 |
Cutting edge: IL-36 receptor promotes resolution of intestinal damage O Medina-Contreras, A Harusato, H Nishio, KL Flannigan, V Ngo, G Leoni, ... The journal of immunology 196 (1), 34-38, 2016 | 148 | 2016 |
IL-17A-mediated neutrophil recruitment limits expansion of segmented filamentous bacteria KL Flannigan, VL Ngo, D Geem, A Harusato, SA Hirota, CA Parkos, ... Mucosal immunology 10 (3), 673-684, 2017 | 138 | 2017 |
Targeting intestinal inflammation with CD98 siRNA/PEI–loaded nanoparticles H Laroui, D Geem, B Xiao, E Viennois, P Rakhya, T Denning, D Merlin Molecular Therapy 22 (1), 69-80, 2014 | 126 | 2014 |
T lymphocytes and vascular inflammation contribute to stress-dependent hypertension PJ Marvar, A Vinh, S Thabet, HE Lob, D Geem, KJ Ressler, DG Harrison Biological psychiatry 71 (9), 774-782, 2012 | 121 | 2012 |
A cytokine network involving IL-36γ, IL-23, and IL-22 promotes antimicrobial defense and recovery from intestinal barrier damage VL Ngo, H Abo, E Maxim, A Harusato, D Geem, O Medina-Contreras, ... Proceedings of the National Academy of Sciences 115 (22), E5076-E5085, 2018 | 111 | 2018 |
Isolation and characterization of dendritic cells and macrophages from the mouse intestine D Geem, O Medina-Contreras, W Kim, CS Huang, TL Denning Journal of visualized experiments: JoVE, 4040, 2012 | 76 | 2012 |
Intestinal antigen-presenting cells: key regulators of immune homeostasis and inflammation KL Flannigan, D Geem, A Harusato, TL Denning The American journal of pathology 185 (7), 1809-1819, 2015 | 67 | 2015 |
Small intestinal intraepithelial TCRγδ+ T lymphocytes are present in the premature intestine but selectively reduced in surgical necrotizing enterocolitis JH Weitkamp, MJ Rosen, Z Zhao, T Koyama, D Geem, TL Denning, ... PLoS One 9 (6), e99042, 2014 | 62 | 2014 |
Cortisol, stress, and attentional bias toward threat RK McHugh, E Behar, CA Gutner, D Geem, MW Otto Anxiety, Stress, & Coping 23 (5), 529-545, 2010 | 62 | 2010 |
Specific microbiota-induced intestinal Th17 differentiation requires MHC class II but not GALT and mesenteric lymph nodes D Geem, O Medina-Contreras, M McBride, RD Newberry, PA Koni, ... The Journal of Immunology 193 (1), 431-438, 2014 | 59 | 2014 |
Harnessing regulatory T cells for the treatment of inflammatory bowel disease D Geem, A Harusato, K Flannigan, TL Denning Inflammatory bowel diseases 21 (6), 1409-1418, 2015 | 50 | 2015 |
The “bridging” aspartate 178 in phthalate dioxygenase facilitates interactions between the Rieske center and the iron (II)− mononuclear center M Tarasev, A Pinto, D Kim, SJ Elliott, DP Ballou Biochemistry 45 (34), 10208-10216, 2006 | 35 | 2006 |
Macrophage isolation from the mouse small and large intestine A Harusato, D Geem, TL Denning Gastrointestinal Physiology and Diseases: Methods and Protocols, 171-180, 2016 | 28 | 2016 |
Combined IL-2 Immunocomplex and Anti-IL-5 mAb Treatment Expands Foxp3+ Treg Cells in the Absence of Eosinophilia and Ameliorates Experimental Colitis H Abo, KL Flannigan, D Geem, VL Ngo, A Harusato, TL Denning Frontiers in immunology 10, 459, 2019 | 21 | 2019 |
Contribution of mesenteric lymph nodes and GALT to the intestinal Foxp3+ regulatory T-cell compartment D Geem, V Ngo, A Harusato, B Chassaing, AT Gewirtz, RD Newberry, ... Cellular and molecular gastroenterology and hepatology 2 (3), 274-280. e3, 2016 | 18 | 2016 |
Assessing cellular and transcriptional diversity of ileal mucosa among treatment-naïve and treated Crohn’s disease SC Maddipatla, VL Kolachala, S Venkateswaran, AF Dodd, RS Pelia, ... Inflammatory Bowel Diseases 29 (2), 274-285, 2023 | 17 | 2023 |
Phenotypic and functional profiling of mouse intestinal antigen presenting cells A Harusato, KL Flannigan, D Geem, TL Denning Journal of immunological methods 421, 20-26, 2015 | 15 | 2015 |