Establishment of outgrowth endothelial cells from peripheral blood J Martin-Ramirez, M Hofman, M Van Den Biggelaar, RP Hebbel, ... Nature protocols 7 (9), 1709-1715, 2012 | 188 | 2012 |
Proteomic analyses of human regulatory T cells reveal adaptations in signaling pathways that protect cellular identity E Cuadrado, M van den Biggelaar, S de Kivit, Y Chen, M Slot, I Doubal, ... Immunity 48 (5), 1046-1059. e6, 2018 | 131 | 2018 |
Translational repression of pre-formed cytokine-encoding mRNA prevents chronic activation of memory T cells F Salerno, S Engels, M van den Biggelaar, FPJ van Alphen, A Guislain, ... Nature immunology 19 (8), 828-837, 2018 | 111 | 2018 |
Secreted CLIC3 drives cancer progression through its glutathione-dependent oxidoreductase activity JR Hernandez-Fernaud, E Ruengeler, A Casazza, LJ Neilson, E Pulleine, ... Nature communications 8 (1), 14206, 2017 | 110 | 2017 |
Dynamic transcriptome-proteome correlation networks reveal human myeloid differentiation and neutrophil-specific programming AJ Hoogendijk, F Pourfarzad, CEM Aarts, ATJ Tool, IH Hiemstra, L Grassi, ... Cell reports 29 (8), 2505-2519. e4, 2019 | 103 | 2019 |
Altered glycosylation of platelet-derived von Willebrand factor confers resistance to ADAMTS13 proteolysis RT McGrath, M van den Biggelaar, B Byrne, JM O’Sullivan, O Rawley, ... Blood, The Journal of the American Society of Hematology 122 (25), 4107-4110, 2013 | 99 | 2013 |
CD29 identifies IFN-γ–producing human CD8+ T cells with an increased cytotoxic potential BP Nicolet, A Guislain, FPJ van Alphen, R Gomez-Eerland, ... Proceedings of the National Academy of Sciences 117 (12), 6686-6696, 2020 | 97 | 2020 |
Uptake of blood coagulation factor VIII by dendritic cells is mediated via its C1 domain E Herczenik, SD van Haren, A Wroblewska, P Kaijen, ... Journal of allergy and clinical immunology 129 (2), 501-509. e5, 2012 | 88 | 2012 |
Glucocorticoids induce differentiation of monocytes towards macrophages that share functional and phenotypical aspects with erythroblastic island macrophages E Heideveld, LA Hampton-O’Neil, SJ Cross, FPJ van Alphen, ... Haematologica 103 (3), 395, 2017 | 78 | 2017 |
Emerging roles for von Willebrand factor in cancer cell biology JM O'Sullivan, RJS Preston, T Robson, JS O'Donnell Seminars in thrombosis and hemostasis 44 (02), 159-166, 2018 | 60 | 2018 |
Quantitative phosphoproteomics unveils temporal dynamics of thrombin signaling in human endothelial cells M van den Biggelaar, JR Hernández-Fernaud, BL van den Eshof, ... Blood, The Journal of the American Society of Hematology 123 (12), e22-e36, 2014 | 56 | 2014 |
GPA33: a marker to identify stable human regulatory T cells R Opstelten, S de Kivit, MC Slot, M van den Biggelaar, ... The Journal of Immunology 204 (12), 3139-3148, 2020 | 55 | 2020 |
Factor VIII C1 domain spikes 2092–2093 and 2158–2159 comprise regions that modulate cofactor function and cellular uptake E Bloem, M van den Biggelaar, A Wroblewska, J Voorberg, JH Faber, ... Journal of Biological Chemistry 288 (41), 29670-29679, 2013 | 50 | 2013 |
C1 domain residues Lys 2092 and Phe 2093 are of major importance for the endocytic uptake of coagulation factor VIII H Meems, M Van den Biggelaar, M Rondaij, C Van der Zwaan, K Mertens, ... The international journal of biochemistry & cell biology 43 (8), 1114-1121, 2011 | 50 | 2011 |
Weibel-Palade body localized syntaxin-3 modulates von Willebrand factor secretion from endothelial cells M Schillemans, E Karampini, BL van den Eshof, A Gangaev, M Hofman, ... Arteriosclerosis, thrombosis, and vascular biology 38 (7), 1549-1561, 2018 | 48 | 2018 |
Modification of an exposed loop in the C1 domain reduces immune responses to factor VIII in hemophilia A mice A Wroblewska, SD van Haren, E Herczenik, P Kaijen, A Ruminska, SY Jin, ... Blood, The Journal of the American Society of Hematology 119 (22), 5294-5300, 2012 | 46 | 2012 |
Efficiency of von Willebrand factor‐mediated targeting of interleukin‐8 into Weibel–Palade bodies R Bierings, M Van Den Biggelaar, A Kragt, K Mertens, J Voorberg, ... Journal of Thrombosis and Haemostasis 5 (12), 2512-2519, 2007 | 44 | 2007 |
Differences between platelets derived from neonatal cord blood and adult peripheral blood assessed by mass spectrometry E Stokhuijzen, JM Koornneef, B Nota, BL van den Eshof, FPJ van Alphen, ... Journal of proteome research 16 (10), 3567-3575, 2017 | 42 | 2017 |
Impaired killing of Candida albicans by granulocytes mobilized for transfusion purposes: a role for granule components RP Gazendam, A van de Geer, JL van Hamme, ATJ Tool, DJ van Rees, ... Haematologica 101 (5), 587, 2016 | 42 | 2016 |
Intracellular cotrafficking of factor VIII and von Willebrand factor type 2N variants to storage organelles M van den Biggelaar, AB Meijer, J Voorberg, K Mertens Blood, The Journal of the American Society of Hematology 113 (13), 3102-3109, 2009 | 42 | 2009 |