| Unraveling the scissile bond: how ADAMTS13 recognizes and cleaves von Willebrand factor JTB Crawley, R de Groot, Y Xiang, BM Luken, DA Lane Blood, The Journal of the American Society of Hematology 118 (12), 3212-3221, 2011 | 380 | 2011 |
| Extracellular histones, cell-free DNA, or nucleosomes: differences in immunostimulation G Marsman, S Zeerleder, BM Luken Cell death & disease 7 (12), e2518-e2518, 2016 | 227 | 2016 |
| High VWF, low ADAMTS13, and oral contraceptives increase the risk of ischemic stroke and myocardial infarction in young women HM Andersson, B Siegerink, BM Luken, JTB Crawley, A Algra, DA Lane, ... Blood, The Journal of the American Society of Hematology 119 (6), 1555-1560, 2012 | 194 | 2012 |
| An autoantibody epitope comprising residues R660, Y661, and Y665 in the ADAMTS13 spacer domain identifies a binding site for the A2 domain of VWF W Pos, JTB Crawley, R Fijnheer, J Voorberg, DA Lane, BM Luken Blood, The Journal of the American Society of Hematology 115 (8), 1640-1649, 2010 | 167 | 2010 |
| Conformational activation of ADAMTS13 K South, BM Luken, JTB Crawley, R Phillips, M Thomas, RF Collins, ... Proceedings of the National Academy of Sciences 111 (52), 18578-18583, 2014 | 164 | 2014 |
| The spacer domain of ADAMTS13 contains a major binding site for antibodies in patients with thrombotic thrombocytopenic purpura BM Luken, EAM Turenhout, JJJ Hulstein, JA Van Mourik, R Fijnheer, ... Thrombosis and haemostasis 93 (02), 267-283, 2005 | 154 | 2005 |
| Autoregulation of von Willebrand factor function by a disulfide bond switch D Butera, F Passam, L Ju, KM Cook, H Woon, C Aponte-Santamaría, ... Science advances 4 (2), eaaq1477, 2018 | 94 | 2018 |
| Evidence for a role of anti-ADAMTS13 autoantibodies despite normal ADAMTS13 activity in recurrent thrombotic thrombocytopenic purpura R Froehlich-Zahnd, JN George, SK Vesely, DR Terrell, K Aboulfatova, ... Haematologica 97 (2), 297, 2012 | 89 | 2012 |
| Multiple B‐cell clones producing antibodies directed to the spacer and disintegrin/thrombospondin type‐1 repeat 1 (TSP1) of ADAMTS13 in a patient with acquired thrombotic … BM Luken, PHP Kaijen, EAM Turenhout, JAK Hovinga, JA Van Mourik, ... Journal of thrombosis and haemostasis 4 (11), 2355-2364, 2006 | 88 | 2006 |
| VH1‐69 germline encoded antibodies directed towards ADAMTS13 in patients with acquired thrombotic thrombocytopenic purpura W Pos, BM Luken, EAM Turenhout, F Scheiflinger, JF Dong, R Fijnheer, ... Journal of thrombosis and haemostasis 7 (3), 421-428, 2009 | 87 | 2009 |
| Amino acid regions 572–579 and 657–666 of the spacer domain of ADAMTS13 provide a common antigenic core required for binding of antibodies in patients with acquired TTP BM Luken, EAM Turenhout, PHP Kaijen, MJ Greuter, W Pos, ... Thrombosis and haemostasis 96 (09), 295-301, 2006 | 79 | 2006 |
| The importance of vicinal cysteines, C1669 and C1670, for von Willebrand factor A2 domain function BM Luken, LYN Winn, J Emsley, DA Lane, JTB Crawley Blood, The Journal of the American Society of Hematology 115 (23), 4910-4913, 2010 | 63 | 2010 |
| Activated protein C cofactor function of protein S: a critical role for Asp95 in the EGF1-like domain HM Andersson, MJ Arantes, JTB Crawley, BM Luken, S Tran, B Dahlbäck, ... Blood, The Journal of the American Society of Hematology 115 (23), 4878-4885, 2010 | 54 | 2010 |
| Humoral immune response to ADAMTS13 in acquired thrombotic thrombocytopenic purpura W Pos, BM Luken, N Sorvillo, JAK Hovinga, J Voorberg Journal of thrombosis and haemostasis 9 (7), 1285-1291, 2011 | 52 | 2011 |
| Coagulation factor XI improves host defence during murine pneumonia-derived sepsis independent of factor XII activation I Stroo, S Zeerleder, C Ding, BM Luken, JJTH Roelofs, OJ de Boer, ... Thrombosis and haemostasis 117 (08), 1601-1614, 2017 | 46 | 2017 |
| Control of VWF A2 domain stability and ADAMTS13 access to the scissile bond of full-length VWF CJ Lynch, DA Lane, BM Luken Blood, The Journal of the American Society of Hematology 123 (16), 2585-2592, 2014 | 41 | 2014 |
| DNA and factor VII–activating protease protect against the cytotoxicity of histones G Marsman, H von Richthofen, I Bulder, F Lupu, J Hazelzet, BM Luken, ... Blood advances 1 (26), 2491-2502, 2017 | 40 | 2017 |
| Role of platelets, neutrophils, and factor XII in spontaneous venous thrombosis in mice M Heestermans, S Salloum-Asfar, D Salvatori, EH Laghmani, BM Luken, ... Blood, The Journal of the American Society of Hematology 127 (21), 2630-2637, 2016 | 40 | 2016 |
| Dynamics of von Willebrand factor reactivity in sickle cell disease during vaso‐occlusive crisis and steady state JWR Sins, M Schimmel, BM Luken, E Nur, SS Zeerleder, CFJ van Tuijn, ... Journal of Thrombosis and Haemostasis 15 (7), 1392-1402, 2017 | 38 | 2017 |
| Mouse venous thrombosis upon silencing of anticoagulants depends on tissue factor and platelets, not FXII or neutrophils M Heestermans, S Salloum-Asfar, T Streef, EH Laghmani, D Salvatori, ... Blood, The Journal of the American Society of Hematology 133 (19), 2090-2099, 2019 | 33 | 2019 |
Wouter PosPhDVerified email at vectorytx.com