New quinoxaline derivatives as VEGFR-2 inhibitors with anticancer and apoptotic activity: Design, molecular modeling, and synthesis NA Alsaif, MA Dahab, MM Alanazi, AJ Obaidullah, AA Al-Mehizia, ... Bioorganic Chemistry 110, 104807, 2021 | 84 | 2021 |
Design, synthesis, docking, ADMET studies, and anticancer evaluation of new 3-methylquinoxaline derivatives as VEGFR-2 inhibitors and apoptosis inducers MM Alanazi, IH Eissa, NA Alsaif, AJ Obaidullah, WA Alanazi, AF Alasmari, ... Journal of Enzyme Inhibition and Medicinal Chemistry 36 (1), 1760-1782, 2021 | 79 | 2021 |
New bis ([1, 2, 4] triazolo)[4, 3-a: 3′, 4′-c] quinoxaline derivatives as VEGFR-2 inhibitors and apoptosis inducers: Design, synthesis, in silico studies, and anticancer … MM Alanazi, HA Mahdy, NA Alsaif, AJ Obaidullah, HM Alkahtani, ... Bioorganic Chemistry 112, 104949, 2021 | 78 | 2021 |
Novel thiophene Chalcones-Coumarin as acetylcholinesterase inhibitors: Design, synthesis, biological evaluation, molecular docking, ADMET prediction and molecular dynamics … AH Hasan, S Murugesan, SI Amran, S Chander, MM Alanazi, TB Hadda, ... Bioorganic Chemistry 119, 105572, 2022 | 64 | 2022 |
A potential anticancer dihydropyrimidine derivative and its protein binding mechanism by multispectroscopic, molecular docking and molecular dynamic simulation along with its … TA Wani, N Alsaif, MM Alanazi, AH Bakheit, S Zargar, MA Bhat European Journal of Pharmaceutical Sciences 158, 105686, 2021 | 60 | 2021 |
Synthesis, cytotoxic evaluation, and molecular docking studies of novel quinazoline derivatives with benzenesulfonamide and anilide tails: Dual inhibitors of EGFR/HER2 HM Alkahtani, AN Abdalla, AJ Obaidullah, MM Alanazi, AA Almehizia, ... Bioorganic Chemistry 95, 103461, 2020 | 60 | 2020 |
New quinoxaline-based VEGFR-2 inhibitors: Design, synthesis, and antiproliferative evaluation with in silico docking, ADMET, toxicity, and DFT studies MM Alanazi, H Elkady, NA Alsaif, AJ Obaidullah, HM Alkahtani, ... RSC advances 11 (48), 30315-30328, 2021 | 58 | 2021 |
Binding of colchicine and ascorbic acid (vitamin C) to bovine serum albumin: An in-vitro interaction study using multispectroscopic, molecular docking and molecular dynamics … TA Wani, NA Alsaif, MM Alanazi, AH Bakheit, AA Khan, S Zargar Journal of Molecular Liquids 342, 117542, 2021 | 54 | 2021 |
Synthesis, anticancer, apoptosis-inducing activities and EGFR and VEGFR2 assay mechanistic studies of 5, 5-diphenylimidazolidine-2, 4-dione derivatives: Molecular docking studies HM Alkahtani, MM Alanazi, FS Aleanizy, FY Alqahtani, A Alhoshani, ... Saudi Pharmaceutical Journal 27 (5), 682-693, 2019 | 54 | 2019 |
Synthesis, in vitro thymidine phosphorylase inhibitory activity and molecular docking study of novel pyridine-derived bis-oxadiazole bearing bis-schiff base derivatives R Hussain, W Rehman, F Rahim, S Khan, AS Alanazi, MM Alanazi, ... Arabian Journal of Chemistry 16 (6), 104773, 2023 | 52 | 2023 |
Discovery of new VEGFR-2 inhibitors based on bis([1, 2, 4]triazolo)[4,3-a:3',4'-c]quinoxaline derivatives as anticancer agents and apoptosis inducers NA Alsaif, MS Taghour, MM Alanazi, AJ Obaidullah, AA Al-Mehizia, ... Journal of enzyme inhibition and medicinal chemistry 36 (1), 1093-1114, 2021 | 51 | 2021 |
Mechanistic interaction study of 5, 6-Dichloro-2-[2-(pyridin-2-yl) ethyl] isoindoline-1, 3-dione with bovine serum albumin by spectroscopic and molecular docking approaches MM Alanazi, AA Almehizia, AH Bakheit, NA Alsaif, HM Alkahtani, TA Wani Saudi Pharmaceutical Journal 27 (3), 341-347, 2019 | 47 | 2019 |
Discovery of new quinoxaline-based derivatives as anticancer agents and potent VEGFR-2 inhibitors: Design, synthesis, and in silico study MM Alanazi, H Elkady, NA Alsaif, AJ Obaidullah, WA Alanazi, ... Journal of Molecular Structure 1253, 132220, 2022 | 45 | 2022 |
Immunoinformatics-guided design of a multi-epitope vaccine based on the structural proteins of severe acute respiratory syndrome coronavirus 2 AJ Obaidullah, MM Alanazi, NA Alsaif, H Albassam, AA Almehizia, ... RSC advances 11 (29), 18103-18121, 2021 | 42 | 2021 |
Discovery of new 3-methylquinoxalines as potential anti-cancer agents and apoptosis inducers targeting VEGFR-2: design, synthesis, and in silico studies MM Alanazi, A Elwan, NA Alsaif, AJ Obaidullah, HM Alkahtani, ... Journal of Enzyme Inhibition and Medicinal Chemistry 36 (1), 1732-1750, 2021 | 42 | 2021 |
Interaction characterization of a tyrosine kinase inhibitor erlotinib with a model transport protein in the presence of quercetin: A drug–protein and drug–drug interaction … TA Wani, MM Alanazi, NA Alsaif, AH Bakheit, S Zargar, OM Alsalami, ... Molecules 27 (4), 1265, 2022 | 41 | 2022 |
Design, synthesis, and carbonic anhydrase inhibition activity of benzenesulfonamide-linked novel pyrazoline derivatives AM Alaa, AS El-Azab, S Bua, A Nocentini, MAA El-Enin, MM Alanazi, ... Bioorganic chemistry 87, 425-431, 2019 | 39 | 2019 |
Molecular modeling and DFT studies on the antioxidant activity of Centaurea scoparia flavonoids and molecular dynamics simulation of their interaction with β-lactoglobulin EM Kamel, A Bin-Ammar, AA El-Bassuony, MM Alanazi, A Altharawi, ... RSC advances 13 (18), 12361-12374, 2023 | 33 | 2023 |
Identification of new [1, 2, 4] triazolo [4, 3-a] quinoxalines as potent VEGFR-2 tyrosine kinase inhibitors: Design, synthesis, anticancer evaluation, and in silico studies NA Alsaif, MS Taghour, MM Alanazi, AJ Obaidullah, WA Alanazi, ... Bioorganic & Medicinal Chemistry 46, 116384, 2021 | 30 | 2021 |
S-substituted 2-mercaptoquinazolin-4 (3H)-one and 4-ethylbenzensulfonamides act as potent and selective human carbonic anhydrase IX and XII inhibitors AS El-Azab, AAM Abdel-Aziz, S Bua, A Nocentini, NA AlSaif, MM Alanazi, ... Journal of Enzyme Inhibition and Medicinal Chemistry 35 (1), 733-743, 2020 | 29 | 2020 |