| The translation of cell-based therapies: clinical landscape and manufacturing challenges TRJ Heathman, AW Nienow, MJ McCall, K Coopman, B Kara, CJ Hewitt Regenerative medicine 10 (1), 49-64, 2015 | 351 | 2015 |
| Expansion, harvest and cryopreservation of human mesenchymal stem cells in a serum‐free microcarrier process TRJ Heathman, VAM Glyn, A Picken, QA Rafiq, K Coopman, AW Nienow, ... Biotechnology and bioengineering 112 (8), 1696-1707, 2015 | 110 | 2015 |
| Agitation conditions for the culture and detachment of hMSCs from microcarriers in multiple bioreactor platforms AW Nienow, CJ Hewitt, TRJ Heathman, VAM Glyn, GN Fonte, MP Hanga, ... Biochemical Engineering Journal 108, 24-29, 2016 | 109 | 2016 |
| Characterization of human mesenchymal stem cells from multiple donors and the implications for large scale bioprocess development TRJ Heathman, QA Rafiq, AKC Chan, K Coopman, AW Nienow, B Kara, ... Biochemical engineering journal 108, 14-23, 2016 | 107 | 2016 |
| Bioreactors for cell therapies: Current status and future advances S Eaker, E Abraham, J Allickson, TA Brieva, D Baksh, TRJ Heathman, ... Cytotherapy 19 (1), 9-18, 2017 | 59 | 2017 |
| Serum-free process development: improving the yield and consistency of human mesenchymal stromal cell production TRJ Heathman, A Stolzing, C Fabian, QA Rafiq, K Coopman, AW Nienow, ... Cytotherapy 17 (11), 1524-1535, 2015 | 55 | 2015 |
| Qualitative and quantitative demonstration of bead-to-bead transfer with bone marrow-derived human mesenchymal stem cells on microcarriers: Utilising the phenomenon to improve … QA Rafiq, S Ruck, MP Hanga, TRJ Heathman, K Coopman, AW Nienow, ... Biochemical Engineering Journal 135, 11-21, 2018 | 54 | 2018 |
| Process development of human multipotent stromal cell microcarrier culture using an automated high‐throughput microbioreactor QA Rafiq, MP Hanga, TRJ Heathman, K Coopman, AW Nienow, ... Biotechnology and bioengineering 114 (10), 2253-2266, 2017 | 54 | 2017 |
| Scalability and process transfer of mesenchymal stromal cell production from monolayer to microcarrier culture using human platelet lysate TRJ Heathman, A Stolzing, C Fabian, QA Rafiq, K Coopman, AW Nienow, ... Cytotherapy 18 (4), 523-535, 2016 | 53 | 2016 |
| Demonstrating the manufacture of human CAR‐T cells in an automated stirred‐tank bioreactor E Costariol, MC Rotondi, A Amini, CJ Hewitt, AW Nienow, TRJ Heathman, ... Biotechnology Journal 15 (9), 2000177, 2020 | 43 | 2020 |
| Agitation and aeration of stirred-bioreactors for the microcarrier culture of human mesenchymal stem cells and potential implications for large-scale bioprocess development TRJ Heathman, AW Nienow, QA Rafiq, K Coopman, B Kara, CJ Hewitt Biochemical Engineering Journal 136, 9-17, 2018 | 42 | 2018 |
| Investigation of Localized Delivery of Diclofenac Sodium from Poly(D,L-Lactic Acid-co-Glycolic Acid)/Poly(Ethylene Glycol) Scaffolds Using an In Vitro Osteoblast … LE Sidney, TRJ Heathman, ER Britchford, A Abed, CV Rahman, ... Tissue Engineering Part A 21 (1-2), 362-373, 2015 | 42 | 2015 |
| Establishing the scalable manufacture of primary human T‐cells in an automated stirred‐tank bioreactor E Costariol, M Rotondi, A Amini, CJ Hewitt, AW Nienow, TRJ Heathman, ... Biotechnology and bioengineering 116 (10), 2488-2502, 2019 | 39 | 2019 |
| Bioreactor engineering fundamentals for stem cell manufacturing AW Nienow, K Coopman, TRJ Heathman, QA Rafiq, CJ Hewitt Stem cell manufacturing, 43-75, 2016 | 32 | 2016 |
| Multiparameter flow cytometry for the characterisation of extracellular markers on human mesenchymal stem cells AKC Chan, TRJ Heathman, K Coopman, CJ Hewitt Biotechnology letters 36, 731-741, 2014 | 30 | 2014 |
| Towards automated manufacturing for cell therapies D Smith, TRJ Heathman, A Klarer, C LeBlon, Y Tada, B Hampson Current hematologic malignancy reports 14, 278-285, 2019 | 20 | 2019 |
| Development of a process control strategy for the serum-free microcarrier expansion of human mesenchymal stem cells towards cost-effective and commercially viable manufacturing TRJ Heathman, AW Nienow, QA Rafiq, K Coopman, B Kara, CJ Hewitt Biochemical engineering journal 141, 200-209, 2019 | 19 | 2019 |
| Controlled production of poly (3-hydroxybutyrate-co-3-hydroxyhexanoate)(PHBHHx) nanoparticles for targeted and sustained drug delivery TRJ Heathman, WR Webb, J Han, Z Dan, GQ Chen, NR Forsyth, AJ El Haj, ... Journal of Pharmaceutical Sciences 103 (8), 2498-2508, 2014 | 19 | 2014 |
| Scalable manufacture for cell therapy needs QA Rafiq, TRJ Heathman, K Coopman, AW Nienow, CJ Hewitt Bioreactors: Design, Operation and Novel Applications, 113-146, 2016 | 13 | 2016 |
| Stem cell manufacturing AW Nienow, K Coopman, TR Heathman, QA Rafiq, CJ Hewitt Elsevier, 2016 | 10 | 2016 |
Alvin NienowUniversity of BirminghamVerified email at bham.ac.uk