Endothelial-cell FAK targeting sensitizes tumours to DNA-damaging therapy B Tavora, LE Reynolds, S Batista, F Demircioglu, I Fernandez, ... Nature 514 (7520), 112-116, 2014 | 186 | 2014 |
Ionizing radiation-induced NF-κB activation requires PARP-1 function to confer radioresistance SJ Veuger, JE Hunter, BW Durkacz Oncogene 28 (6), 832-842, 2009 | 167 | 2009 |
The clinical development candidate CCT245737 is an orally active CHK1 inhibitor with preclinical activity in RAS mutant NSCLC and Eμ-MYC driven B-cell lymphoma MI Walton, PD Eve, A Hayes, AT Henley, MR Valenti, AKDH Brandon, ... Oncotarget 7 (3), 2329, 2016 | 79 | 2016 |
c-Rel and its many roles in cancer: an old story with new twists JE Hunter, J Leslie, ND Perkins British journal of cancer 114 (1), 1-6, 2016 | 66 | 2016 |
NF-κB mediates radio-sensitization by the PARP-1 inhibitor, AG-014699 JE Hunter, E Willmore, JAE Irving, Z Hostomsky, SJ Veuger, BW Durkacz Oncogene 31 (2), 251-264, 2012 | 50 | 2012 |
The NF-κB subunit c-Rel regulates Bach2 tumour suppressor expression in B-cell lymphoma JE Hunter, JA Butterworth, B Zhao, H Sellier, KJ Campbell, HD Thomas, ... Oncogene 35 (26), 3476-3484, 2016 | 44 | 2016 |
PARP1 expression, activity and ex vivo sensitivity to the PARP inhibitor, talazoparib (BMN 673), in chronic lymphocytic leukaemia A Herriott, SJ Tudhope, G Junge, N Rodrigues, MJ Patterson, ... Oncotarget 6 (41), 43978, 2015 | 40 | 2015 |
A RelA (p65) Thr505 phospho-site mutation reveals an important mechanism regulating NF-κB-dependent liver regeneration and cancer A Moles, JA Butterworth, A Sanchez, JE Hunter, J Leslie, H Sellier, ... Oncogene 35 (35), 4623-4632, 2016 | 38 | 2016 |
Using body temperature, food and water consumption as biomarkers of disease progression in mice with E μ-myc lymphoma JE Hunter, J Butterworth, ND Perkins, M Bateson, CA Richardson British journal of cancer 110 (4), 928-934, 2014 | 35 | 2014 |
Centrosome dysfunction associated with somatic expression of the synaptonemal complex protein TEX12 S Sandhu, IF Sou, JE Hunter, L Salmon, CL Wilson, ND Perkins, N Hunter, ... Communications Biology 4 (1), 1-13, 2021 | 15 | 2021 |
Regulation of CHK1 inhibitor resistance by a c-Rel and USP1 dependent pathway JE Hunter, AE Campbell, NL Hannaway, S Kerridge, S Luli, ... bioRxiv, 2021 | 10 | 2021 |
A pseudo-meiotic centrosomal function of TEX12 in cancer S Sandhu, LJ Salmon, JE Hunter, CL Wilson, ND Perkins, N Hunter, ... bioRxiv, 509869, 2019 | 6 | 2019 |
Regulation of checkpoint kinase signalling and tumorigenesis by the NF-κB regulated gene, CLSPN JE Hunter, JA Butterworth, H Sellier, S Luli, A Floudas, AJ Moore, ... bioRxiv, 358291, 2018 | 4 | 2018 |
PB S-1086, a “Pan-Rel” inhibitor, decreases viability of chronic lymphocytic leukemia cells SJ Tudhope, EA Mulligan, JE Hunter, GP Summerfield, S Marshall, ... Blood, The Journal of the American Society of Hematology 120 (21), 867-867, 2012 | 3 | 2012 |
DNA damage response gene expression in CHK1 inhibitor responsive and resistant mouse models of MYC driven B-cell lymphoma NL Hannaway, JE Hunter, A Greystoke, ND Perkins Cancer Research 79 (13 Supplement), 2548-2548, 2019 | 2 | 2019 |
Abstract A119: A proteomics‐based approach to identify biomarker profiles of homologous recombination deficiency (HRD) in breast cancer cell lines JE Prime, L Unwin, J Hunter, R Allum, JA Nickson, R Rowlinson, ... Molecular Cancer Therapeutics 8 (12 Supplement), A119-A119, 2009 | 2 | 2009 |
A proteomics-based approach to identify biomarker profiles of homologous recombination deficiency (HRD) in breast cancer cell lines JE Prime, L Unwin, J Hunter, R Allum, JA Nickson, R Rowlinson, ... MOLECULAR CANCER THERAPEUTICS 8 (12), 2009 | 2 | 2009 |
Relationships Between Aberrant Activity of the NF-κB Subunits and Outcome In Chronic Lymphocytic Leukemia: The Dual Role of DNA Damage Sensor Enzymes EA Mulligan, JE Hunter, AEG Baird, S Elliott, GP Summerfield, K Hamlen, ... Blood 116 (21), 3588, 2010 | 1 | 2010 |
The radiosensitizing and cytotoxic effects of PBS-1086, a Rel inhibitor of NF-KB, in breast cancer cells JE Hunter, E Willmore, JAE Irving, DR Sliskovic, D Monie, K Bobb, ... Cancer Research 70 (8 Supplement), 3561-3561, 2010 | 1 | 2010 |
Increased migration and motility in XIAP-null cells mediated by the C-RAF protein kinase LG Russell, LAK Davis, JE Hunter, ND Perkins, NS Kenneth | | 2021 |