| Integrative analysis of 111 reference human epigenomes Roadmap Epigenomics Consortium Integrative analysis coordination Kundaje ... Nature 518 (7539), 317-330, 2015 | 6392* | 2015 |
| Deep learning to improve breast cancer detection on screening mammography L Shen, LR Margolies, JH Rothstein, E Fluder, R McBride, W Sieh Scientific reports 9 (1), 12495, 2019 | 1100 | 2019 |
| Distinct epigenomic landscapes of pluripotent and lineage-committed human cells RD Hawkins, GC Hon, LK Lee, QM Ngo, R Lister, M Pelizzola, LE Edsall, ... Cell stem cell 6 (5), 479-491, 2010 | 1001 | 2010 |
| ngs.plot: Quick mining and visualization of next-generation sequencing data by integrating genomic databases L Shen, N Shao, X Liu, E Nestler BMC genomics 15 (1), 284, 2014 | 870 | 2014 |
| Sex-specific transcriptional signatures in human depression B Labonté, O Engmann, I Purushothaman, C Menard, J Wang, C Tan, ... Nature medicine 23 (9), 1102-1111, 2017 | 695 | 2017 |
| Epigenetic regulation of brain region-specific microglia clearance activity P Ayata, A Badimon, HJ Strasburger, MK Duff, SE Montgomery, YHE Loh, ... Nature neuroscience 21 (8), 1049-1060, 2018 | 430 | 2018 |
| diffReps: detecting differential chromatin modification sites from ChIP-seq data with biological replicates L Shen, NY Shao, X Liu, I Maze, J Feng, EJ Nestler PloS one 8 (6), e65598, 2013 | 413 | 2013 |
| Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3 LA Farrelly, RE Thompson, S Zhao, AE Lepack, Y Lyu, NV Bhanu, ... Nature 567 (7749), 535-539, 2019 | 412 | 2019 |
| Evaluation of combined artificial intelligence and radiologist assessment to interpret screening mammograms T Schaffter, DSM Buist, CI Lee, Y Nikulin, D Ribli, Y Guan, W Lotter, Z Jie, ... JAMA network open 3 (3), e200265-e200265, 2020 | 399 | 2020 |
| Sex differences in nucleus accumbens transcriptome profiles associated with susceptibility versus resilience to subchronic variable stress GE Hodes, ML Pfau, I Purushothaman, HF Ahn, SA Golden, DJ Christoffel, ... Journal of Neuroscience 35 (50), 16362-16376, 2015 | 398 | 2015 |
| Early life stress confers lifelong stress susceptibility in mice via ventral tegmental area OTX2 CJ Peña, HG Kronman, DM Walker, HM Cates, RC Bagot, ... Science 356 (6343), 1185-1188, 2017 | 387 | 2017 |
| Circuit-wide transcriptional profiling reveals brain region-specific gene networks regulating depression susceptibility RC Bagot, HM Cates, I Purushothaman, ZS Lorsch, DM Walker, J Wang, ... Neuron 90 (5), 969-983, 2016 | 341 | 2016 |
| Critical role of histone turnover in neuronal transcription and plasticity I Maze, W Wenderski, KM Noh, RC Bagot, N Tzavaras, I Purushothaman, ... Neuron 87 (1), 77-94, 2015 | 329 | 2015 |
| HDAC2 regulates atypical antipsychotic responses through the modulation of mGlu2 promoter activity M Kurita, T Holloway, A García-Bea, A Kozlenkov, AK Friedman, ... Nature Neuroscience 15 (9), 1245-1254, 2012 | 300 | 2012 |
| β-catenin mediates stress resilience through Dicer1/microRNA regulation C Dias, J Feng, H Sun, NY Shao, MS Mazei-Robison, D Damez-Werno, ... Nature 516 (7529), 51-55, 2014 | 289 | 2014 |
| ENL links histone acetylation to oncogenic gene expression in acute myeloid leukaemia L Wan, H Wen, Y Li, J Lyu, Y Xi, T Hoshii, JK Joseph, X Wang, YHE Loh, ... Nature 543 (7644), 265-269, 2017 | 273 | 2017 |
| Neurobiological Sequelae of Witnessing Stressful Events in Adult Mice BL Warren, VF Vialou, SD Iñiguez, LF Alcantara, KN Wright, J Feng, ... Biological Psychiatry, 2012 | 247 | 2012 |
| Locus-specific epigenetic remodeling controls addiction-and depression-related behaviors EA Heller, HM Cates, CJ Peña, H Sun, N Shao, J Feng, SA Golden, ... Nature neuroscience 17 (12), 1720-1727, 2014 | 243 | 2014 |
| GeneOverlap: Test and visualize gene overlaps L Shen Bioconductor package, 2013 | 239* | 2013 |
| Cocaine dynamically regulates heterochromatin and repetitive element unsilencing in nucleus accumbens I Maze, J Feng, MB Wilkinson, HS Sun, L Shen, EJ Nestler Proceedings of the National Academy of Sciences 108 (7), 3035, 2011 | 218 | 2011 |
Eric NestlerIcahn School of Medicine, Mt SinaiVerified email at mssm.edu