| Making muscle: skeletal myogenesis in vivo and in vitro J Chal, O Pourquié Development 144 (12), 2104-2122, 2017 | 895 | 2017 |
| Differentiation of pluripotent stem cells to muscle fiber to model Duchenne muscular dystrophy J Chal, M Oginuma, Z Al Tanoury, B Gobert, O Sumara, A Hick, F Bousson, ... Nature biotechnology 33 (9), 962-969, 2015 | 458 | 2015 |
| Generation of human muscle fibers and satellite-like cells from human pluripotent stem cells in vitro J Chal, Z Al Tanoury, M Hestin, B Gobert, S Aivio, A Hick, T Cherrier, ... Nature protocols 11 (10), 1833-1850, 2016 | 288 | 2016 |
| Control of the segmentation process by graded MAPK/ERK activation in the chick embryo MC Delfini, J Dubrulle, P Malapert, J Chal, O Pourquié Proceedings of the National Academy of Sciences 102 (32), 11343-11348, 2005 | 210 | 2005 |
| A gradient of glycolytic activity coordinates FGF and Wnt signaling during elongation of the body axis in amniote embryos M Oginuma, P Moncuquet, F Xiong, E Karoly, J Chal, K Guevorkian, ... Developmental cell 40 (4), 342-353. e10, 2017 | 197 | 2017 |
| Oscillations of the snail genes in the presomitic mesoderm coordinate segmental patterning and morphogenesis in vertebrate somitogenesis JK Dale, P Malapert, J Chal, G Vilhais-Neto, M Maroto, T Johnson, ... Developmental cell 10 (3), 355-366, 2006 | 183 | 2006 |
| Novel method for action potential measurements from intact cardiac monolayers with multiwell microelectrode array technology HB Hayes, AM Nicolini, CA Arrowood, SA Chvatal, DW Wolfson, HC Cho, ... Scientific reports 9 (1), 11893, 2019 | 89 | 2019 |
| Recapitulating early development of mouse musculoskeletal precursors of the paraxial mesoderm in vitro J Chal, Z Al Tanoury, M Oginuma, P Moncuquet, B Gobert, A Miyanari, ... Development 145 (6), dev157339, 2018 | 76 | 2018 |
| The Lin28/let-7 pathway regulates the mammalian caudal body axis elongation program DA Robinton, J Chal, EL da Rocha, A Han, AV Yermalovich, M Oginuma, ... Developmental cell 48 (3), 396-405. e3, 2019 | 72 | 2019 |
| Prednisolone rescues Duchenne muscular dystrophy phenotypes in human pluripotent stem cell–derived skeletal muscle in vitro Z Al Tanoury, JF Zimmerman, J Rao, D Sieiro, HM McNamara, T Cherrier, ... Proceedings of the National Academy of Sciences 118 (28), e2022960118, 2021 | 54 | 2021 |
| PAPC couples the segmentation clock to somite morphogenesis by regulating N-cadherin-dependent adhesion J Chal, C Guillot, O Pourquié Development 144 (4), 664-676, 2017 | 41 | 2017 |
| Patterning and differentiation of the vertebrate spine J Chal, O Pourquié The skeletal system 53, 41-116, 2009 | 35 | 2009 |
| The long road to making muscle in vitro O Pourquié, Z Al Tanoury, J Chal Current topics in developmental biology 129, 123-142, 2018 | 31 | 2018 |
| Reconstructing human brown fat developmental trajectory in vitro J Rao, Y Djeffal, J Chal, F Marchianò, CH Wang, Z Al Tanoury, S Gapon, ... Developmental Cell 58 (21), 2359-2375. e8, 2023 | 14 | 2023 |
| Transcriptomics, regulatory syntax, and enhancer identification in mesoderm-induced ESCs at single-cell resolution M Khateb, J Perovanovic, KD Ko, K Jiang, X Feng, N Acevedo-Luna, ... Cell reports 40 (7), 2022 | 11 | 2022 |
| Method for preparing induced paraxial mesoderm progenitor (ipam) cells and their use O Pourquie, J Chal US Patent App. 13/597,442, 2013 | 9 | 2013 |
| Method for preparing induced paraxial mesoderm progenitor (ipam) cells and their use O Pourquie, C Jérôme | 5 | 2014 |
| Leveraging genetic diversity in vitro: Evolution or revolution in cardiac safety assessment? B Fermini, EJ Fine, DD Sullivan, AH Nguyen, J Chal, SL Mobley, ... | 1 | 2018 |
| Transcriptomics, Regulatory Syntax, and Enhancer Identification in Heterogenous Populations of Mesoderm-Induced ESCs at Single-Cell Resolution M Khateb, J Perovanovic, KD Ko, K Jiang, X Feng, N Acevedo-Luna, ... bioRxiv, 2022.03. 29.486247, 2022 | | 2022 |
| Clinical trials-in-a-dish: Different inter-individual drug responses for calcium handling and electrophysiology in a cohort of hiPSC-derived cardiomyocytes B Fermini, DD Sullivan, J Chal, EJ Fine, ST Coyne, A King, J Johnson, ... Journal of Pharmacological and Toxicological Methods 99, 106595, 2019 | | 2019 |
Pourquie OlivierProfessor of Genetics and Pathology, Harvard Medical School and Brigham and Women’s HospitalVerified email at genetics.med.harvard.edu