Rucaparib maintenance treatment for recurrent ovarian carcinoma after response to platinum therapy (ARIEL3): a randomised, double-blind, placebo-controlled, phase 3 trial RL Coleman, AM Oza, D Lorusso, C Aghajanian, A Oaknin, A Dean, ... The Lancet 390 (10106), 1949-1961, 2017 | 1765 | 2017 |
Rucaparib in relapsed, platinum-sensitive high-grade ovarian carcinoma (ARIEL2 Part 1): an international, multicentre, open-label, phase 2 trial EM Swisher, KK Lin, AM Oza, CL Scott, H Giordano, J Sun, GE Konecny, ... The lancet oncology 18 (1), 75-87, 2017 | 1233 | 2017 |
AZD8055 is a potent, selective, and orally bioavailable ATP-competitive mammalian target of rapamycin kinase inhibitor with in vitro and in vivo antitumor activity CM Chresta, BR Davies, I Hickson, T Harding, S Cosulich, SE Critchlow, ... Cancer research 70 (1), 288-298, 2010 | 946 | 2010 |
Discovery of a mutant-selective covalent inhibitor of EGFR that overcomes T790M-mediated resistance in NSCLC AO Walter, RTT Sjin, HJ Haringsma, K Ohashi, J Sun, K Lee, ... Cancer discovery 3 (12), 1404-1415, 2013 | 724 | 2013 |
Circulating tumour DNA profiling reveals heterogeneity of EGFR inhibitor resistance mechanisms in lung cancer patients JJ Chabon, AD Simmons, AF Lovejoy, MS Esfahani, AM Newman, ... Nature communications 7 (1), 1-15, 2016 | 644 | 2016 |
Timing of surgery following SARS-CoV-2 infection: an international prospective cohort study COVIDSurg Collaborative Anaesthesia 76 (6), 748-758, 2021 | 598* | 2021 |
Vascular endothelial cell growth factor receptor 3–mediated activation of lymphatic endothelium is crucial for tumor cell entry and spread via lymphatic vessels Y He, I Rajantie, K Pajusola, M Jeltsch, T Holopainen, S Yla-Herttuala, ... Cancer research 65 (11), 4739-4746, 2005 | 563 | 2005 |
Stable antibody expression at therapeutic levels using the 2A peptide J Fang, JJ Qian, S Yi, TC Harding, GH Tu, M VanRoey, K Jooss Nature biotechnology 23 (5), 584-590, 2005 | 487 | 2005 |
Combined immunotherapy with granulocyte-macrophage colony-stimulating factor-transduced allogeneic prostate cancer cells and ipilimumab in patients with metastatic castration … AJM Van den Eertwegh, J Versluis, HP Van den Berg, SJAM Santegoets, ... The lancet oncology 13 (5), 509-517, 2012 | 409 | 2012 |
Secondary Somatic Mutations Restoring RAD51C and RAD51D Associated with Acquired Resistance to the PARP Inhibitor Rucaparib in High-Grade Ovarian … O Kondrashova, M Nguyen, K Shield-Artin, AV Tinker, NNH Teng, ... Cancer discovery 7 (9), 984-998, 2017 | 404 | 2017 |
BRCA Reversion Mutations in Circulating Tumor DNA Predict Primary and Acquired Resistance to the PARP Inhibitor Rucaparib in High-Grade Ovarian Carcinoma KK Lin, MI Harrell, AM Oza, A Oaknin, I Ray-Coquard, AV Tinker, ... Cancer discovery 9 (2), 210-219, 2019 | 375 | 2019 |
Inhibition of lymphogenous metastasis using adeno-associated virus-mediated gene transfer of a soluble VEGFR-3 decoy receptor JM Lin, AS Lalani, TC Harding, M Gonzalez, WW Wu, B Luan, GH Tu, ... Cancer research 65 (15), 6901-6909, 2005 | 344 | 2005 |
Gene transfer of the JNK interacting protein-1 protects dopaminergic neurons in the MPTP model of Parkinson's disease XG Xia, T Harding, M Weller, A Bieneman, JB Uney, JB Schulz Proceedings of the National Academy of Sciences 98 (18), 10433-10438, 2001 | 301 | 2001 |
Vascular endothelial growth factor blockade reduces intratumoral regulatory T cells and enhances the efficacy of a GM-CSF–secreting cancer immunotherapy B Li, AS Lalani, TC Harding, B Luan, K Koprivnikar, G Huan Tu, R Prell, ... Clinical Cancer Research 12 (22), 6808-6816, 2006 | 274 | 2006 |
Aurora kinase A drives the evolution of resistance to third-generation EGFR inhibitors in lung cancer KN Shah, R Bhatt, J Rotow, J Rohrberg, V Olivas, VE Wang, G Hemmati, ... Nature medicine 25 (1), 111-118, 2019 | 269 | 2019 |
Virus-mediated transduction of murine retina with adeno-associated virus: effects of viral capsid and genome size GS Yang, M Schmidt, Z Yan, JD Lindbloom, TC Harding, BA Donahue, ... Journal of virology 76 (15), 7651-7660, 2002 | 265 | 2002 |
Methylation of all BRCA1 copies predicts response to the PARP inhibitor rucaparib in ovarian carcinoma O Kondrashova, M Topp, K Nesic, E Lieschke, GY Ho, MI Harrell, ... Nature communications 9 (1), 3970, 2018 | 261 | 2018 |
The construction of men who are nurses as gay T Harding Journal of advanced nursing 60 (6), 636-644, 2007 | 250 | 2007 |
Sexualizing men's touch: male nurses and the use of intimate touch in clinical practice T Harding, N North, R Perkins Research and theory for nursing practice 22 (2), 88-102, 2008 | 175 | 2008 |
Switching transgene expression in the brain using an adenoviral tetracycline-regulatable system TC Harding, BJ Geddes, D Murphy, D Knight, JB Uney Nature biotechnology 16 (6), 553-555, 1998 | 164 | 1998 |