Mechanisms and function of substrate recruitment by F-box proteins JR Skaar, JK Pagan, M Pagano Nature reviews Molecular cell biology 14 (6), 369-381, 2013 | 731 | 2013 |
SCF ubiquitin ligase-targeted therapies JR Skaar, JK Pagan, M Pagano Nature reviews Drug discovery 13 (12), 889-903, 2014 | 354 | 2014 |
FBXO11 targets BCL6 for degradation and is inactivated in diffuse large B-cell lymphomas S Duan, L Cermak, JK Pagan, M Rossi, C Martinengo, PF Di Celle, ... Nature 481 (7379), 90-93, 2012 | 320 | 2012 |
PTEN counteracts FBXL2 to promote IP3R3- and Ca2+-mediated apoptosis limiting tumour growth S Kuchay, C Giorgi, D Simoneschi, J Pagan, S Missiroli, A Saraf, ... Nature 546 (7659), 554-558, 2017 | 237 | 2017 |
SnapShot: F box proteins I JR Skaar, JK Pagan, M Pagano Cell 137 (6), 1160-1160. e1, 2009 | 211 | 2009 |
The t-SNARE syntaxin 4 is regulated during macrophage activation to function in membrane traffic and cytokine secretion JK Pagan, FG Wylie, S Joseph, C Widberg, NJ Bryant, DE James, JL Stow Current Biology 13 (2), 156-160, 2003 | 166 | 2003 |
Role of the ubiquitin proteasome system in the heart J Pagan, T Seto, M Pagano, A Cittadini Circulation research 112 (7), 1046-1058, 2013 | 153 | 2013 |
Cell cycle checkpoint defects contribute to genomic instability in PTEN deficient cells independent of DNA DSB repair A Gupta, Q Yang, RK Pandita, CR Hunt, T Xiang, S Misri, S Zeng, J Pagan, ... Cell cycle 8 (14), 2198-2210, 2009 | 151 | 2009 |
Cytokine secretion via cholesterol-rich lipid raft-associated SNAREs at the phagocytic cup JG Kay, RZ Murray, JK Pagan, JL Stow Journal of Biological Chemistry 281 (17), 11949-11954, 2006 | 134 | 2006 |
A novel corepressor, BCoR-L1, represses transcription through an interaction with CtBP JK Pagan, J Arnold, KJ Hanchard, R Kumar, T Bruno, MJK Jones, ... Journal of Biological Chemistry 282 (20), 15248-15257, 2007 | 94 | 2007 |
Degradation of Cep68 and PCNT cleavage mediate Cep215 removal from the PCM to allow centriole separation, disengagement and licensing JK Pagan, A Marzio, MJK Jones, A Saraf, PV Jallepalli, L Florens, ... Nature cell biology 17 (1), 31-43, 2015 | 89 | 2015 |
Endocytosis of uncleaved tumor necrosis factor-α in macrophages W Shurety, JK Pagan, JB Prins, JL Stow Laboratory investigation 81 (1), 107-117, 2001 | 57 | 2001 |
PARP1-dependent recruitment of the FBXL10-RNF68-RNF2 ubiquitin ligase to sites of DNA damage controls H2A. Z loading G Rona, D Roberti, Y Yin, JK Pagan, H Homer, E Sassani, A Zeke, ... Elife 7, e38771, 2018 | 51 | 2018 |
Phosphorylation of Ser72 is dispensable for Skp2 assembly into an active SCF ubiquitin ligase and its subcellular localization T Bashir, JK Pagan, L Busino, M Pagano Cell cycle 9 (5), 971-974, 2010 | 39 | 2010 |
FBXL4 suppresses mitophagy by restricting the accumulation of NIX and BNIP3 mitophagy receptors GT Nguyen‐Dien, KL Kozul, Y Cui, B Townsend, PG Kulkarni, SS Ooi, ... The EMBO Journal 42 (13), e112767, 2023 | 36 | 2023 |
FEM1 proteins are ancient regulators of SLBP degradation JF Dankert, JK Pagan, NG Starostina, ET Kipreos, M Pagano Cell Cycle 16 (6), 556-564, 2017 | 28 | 2017 |
FBXW5 controls centrosome number J Pagan, M Pagano Nature cell biology 13 (8), 888-890, 2011 | 16 | 2011 |
PPTC7 maintains mitochondrial protein content by suppressing receptor-mediated mitophagy NM Niemi, LR Serrano, LK Muehlbauer, CE Balnis, L Wei, AJ Smith, ... Nature communications 14 (1), 6431, 2023 | 13 | 2023 |
Centrosome reduction promotes terminal differentiation of human cardiomyocytes DCH Ng, DK Richards, RJ Mills, UY Ho, HL Perks, CR Tucker, HK Voges, ... Stem Cell Reports 15 (4), 817-826, 2020 | 13 | 2020 |
PPTC7 antagonizes mitophagy by promoting BNIP3 and NIX degradation via SCFFBXL4 GT Nguyen-Dien, B Townsend, PG Kulkarni, KL Kozul, SS Ooi, ... EMBO reports 25 (8), 3324-3347, 2024 | 5 | 2024 |