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Optimized gene editing technology for Drosophila melanogaster using germ line-specific Cas9 X Ren, J Sun, BE Housden, Y Hu, C Roesel, S Lin, LP Liu, Z Yang, D Mao, ... Proceedings of the National Academy of Sciences 110 (47), 19012-19017, 2013 | 434 | 2013 |
Seipin is required for converting nascent to mature lipid droplets H Wang, M Becuwe, BE Housden, C Chitraju, AJ Porras, MM Graham, ... Elife 5, 2016 | 377 | 2016 |
A gene-specific T2A-GAL4 library for Drosophila PT Lee, J Zirin, O Kanca, WW Lin, KL Schulze, D Li-Kroeger, R Tao, ... Elife 7, e35574, 2018 | 254 | 2018 |
Loss-of-function genetic tools for animal models: cross-species and cross-platform differences BE Housden, M Muhar, M Gemberling, CA Gersbach, DYR Stainier, ... Nature Reviews Genetics 18 (1), 24, 2017 | 225 | 2017 |
Direct response to Notch activation: signaling crosstalk and incoherent logic A Krejčí, F Bernard, BE Housden, S Collins, SJ Bray Sci. Signal. 2 (55), ra1-ra1, 2009 | 189 | 2009 |
mTORC1 Couples Nucleotide Synthesis to Nucleotide Demand Resulting in a Targetable Metabolic Vulnerability AJ Valvezan, M Turner, A Belaid, HC Lam, SK Miller, MC McNamara, ... Cancer Cell, 2017 | 154 | 2017 |
In vivo transcriptional activation using CRISPR/Cas9 in Drosophila S Lin, B Ewen-Campen, X Ni, BE Housden, N Perrimon Genetics 201 (2), 433-442, 2015 | 148 | 2015 |
Identification of potential drug targets for tuberous sclerosis complex by synthetic screens combining CRISPR-based knockouts with RNAi BE Housden, AJ Valvezan, C Kelley, R Sopko, Y Hu, C Roesel, S Lin, ... Sci. Signal. 8 (393), rs9-rs9, 2015 | 141 | 2015 |
CRISPR guide RNA design for research applications SE Mohr, Y Hu, B Ewen‐Campen, BE Housden, R Viswanatha, ... The FEBS journal 283 (17), 3232-3238, 2016 | 116 | 2016 |
Resources for functional genomics studies in Drosophila melanogaster SE Mohr, Y Hu, K Kim, BE Housden, N Perrimon Genetics 197 (1), 1-18, 2014 | 77 | 2014 |
Specificity of Notch pathway activation: twist controls the transcriptional output in adult muscle progenitors F Bernard, A Krejci, B Housden, B Adryan, SJ Bray Development 137 (16), 2633-2642, 2010 | 77 | 2010 |
Spatial and temporal organization of signaling pathways BE Housden, N Perrimon Trends in biochemical sciences 39 (10), 457-464, 2014 | 73 | 2014 |
Transcriptional dynamics elicited by a short pulse of notch activation involves feed-forward regulation by E (spl)/Hes genes BE Housden, AQ Fu, A Krejci, F Bernard, B Fischer, S Tavaré, S Russell, ... PLoS genetics 9 (1), e1003162, 2013 | 72 | 2013 |
Drosophila reporter vectors compatible with ΦC31 integrase transgenesis techniques and their use to generate new Notch reporter fly lines BE Housden, K Millen, SJ Bray G3: Genes| Genomes| Genetics 2 (1), 79-82, 2012 | 66 | 2012 |
Abstract C124: HIF-independent synthetic lethality between CDK4/6 inhibition and VHL loss across species H Nicholson, B Housden, N Perrimon, WG Kaelin Molecular Cancer Therapeutics 18 (12 Supplement), C124-C124, 2019 | 65* | 2019 |
HIF-independent synthetic lethality between CDK4/6 inhibition and VHL loss across species HE Nicholson, Z Tariq, BE Housden, RB Jennings, LA Stransky, ... Science Signaling 12 (601), eaay0482, 2019 | 65 | 2019 |
Comparing CRISPR and RNAi-based screening technologies BE Housden, N Perrimon Nature biotechnology 34 (6), 621-623, 2016 | 62 | 2016 |
Mapping signaling pathway cross-talk in Drosophila cells N Ammeux, BE Housden, A Georgiadis, Y Hu, N Perrimon Proceedings of the National Academy of Sciences 113 (35), 9940-9945, 2016 | 53 | 2016 |