| Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models RU Svensson, SJ Parker, LJ Eichner, MJ Kolar, M Wallace, SN Brun, ... Nature medicine 22 (10), 1108-1119, 2016 | 476 | 2016 |
| miR-378∗ mediates metabolic shift in breast cancer cells via the PGC-1β/ERRγ transcriptional pathway LJ Eichner, MC Perry, CR Dufour, N Bertos, M Park, J St-Pierre, V Giguère Cell metabolism 12 (4), 352-361, 2010 | 344 | 2010 |
| Correlation of mRNA and protein levels: cell type-specific gene expression of cluster designation antigens in the prostate LE Pascal, LD True, DS Campbell, EW Deutsch, M Risk, IM Coleman, ... BMC genomics 9, 1-13, 2008 | 326 | 2008 |
| Estrogen related receptors (ERRs): a new dawn in transcriptional control of mitochondrial gene networks LJ Eichner, V Giguère Mitochondrion 11 (4), 544-552, 2011 | 211 | 2011 |
| Genetic analysis reveals AMPK is required to support tumor growth in murine Kras-dependent lung cancer models LJ Eichner, SN Brun, S Herzig, NP Young, SD Curtis, DB Shackelford, ... Cell metabolism 29 (2), 285-302. e7, 2019 | 190 | 2019 |
| AMPK governs lineage specification through Tfeb-dependent regulation of lysosomes NP Young, A Kamireddy, JL Van Nostrand, LJ Eichner, MN Shokhirev, ... Genes & development 30 (5), 535-552, 2016 | 189 | 2016 |
| Molecular and genetic crosstalks between mTOR and ERRα are key determinants of rapamycin-induced nonalcoholic fatty liver C Chaveroux, LJ Eichner, CR Dufour, A Shatnawi, A Khoutorsky, ... Cell metabolism 17 (4), 586-598, 2013 | 164 | 2013 |
| The homeobox protein Prox1 is a negative modulator of ERRα/PGC-1α bioenergetic functions A Charest-Marcotte, CR Dufour, BJ Wilson, AM Tremblay, LJ Eichner, ... Genes & development 24 (6), 537-542, 2010 | 162 | 2010 |
| The AMPK-related kinases SIK1 and SIK3 mediate key tumor-suppressive effects of LKB1 in NSCLC PE Hollstein, LJ Eichner, SN Brun, A Kamireddy, RU Svensson, LI Vera, ... Cancer discovery 9 (11), 1606-1627, 2019 | 133 | 2019 |
| Transcriptional coregulators: fine-tuning metabolism L Mouchiroud, LJ Eichner, RJ Shaw, J Auwerx Cell metabolism 20 (1), 26-40, 2014 | 127 | 2014 |
| Genomic convergence among ERRα, PROX1, and BMAL1 in the control of metabolic clock outputs CR Dufour, MP Levasseur, NHH Pham, LJ Eichner, BJ Wilson, ... PLoS genetics 7 (6), e1002143, 2011 | 119 | 2011 |
| Application of Affymetrix array and Massively Parallel Signature Sequencing for identification of genes involved in prostate cancer progression AJ Oudes, JC Roach, LS Walashek, LJ Eichner, LD True, RL Vessella, ... BMC cancer 5, 1-12, 2005 | 85 | 2005 |
| The CREB coactivator CRTC2 promotes oncogenesis in LKB1-mutant non–small cell lung cancer L Rodón, RU Svensson, E Wiater, MGH Chun, WW Tsai, LJ Eichner, ... Science advances 5 (7), eaaw6455, 2019 | 41 | 2019 |
| HDAC3 is critical in tumor development and therapeutic resistance in Kras-mutant non–small cell lung cancer LJ Eichner, SD Curtis, SN Brun, CK McGuire, I Gushterova, JT Baumgart, ... Science Advances 9 (11), eadd3243, 2023 | 29 | 2023 |
| Development of the Minimum Information Specification forIn SituHybridization and Immunohistochemistry Experiments (MISFISHIE) EW Deutsch, CA Ball, GS Bova, A Brazma, RE Bumgarner, D Campbell, ... Omics: a journal of integrative biology 10 (2), 205-208, 2006 | 24 | 2006 |
| Estrogen-related receptor α, the molecular clock, and transcriptional control of metabolic outputs V Giguere, CR Dufour, LJ Eichner, G Deblois, N Cermakian Cold Spring Harbor symposia on quantitative biology 76, 57-61, 2011 | 20 | 2011 |
| ERBB2 deficiency alters an E2F-1-dependent adaptive stress response and leads to cardiac dysfunction MC Perry, CR Dufour, LJ Eichner, DWK Tsang, G Deblois, WJ Muller, ... Molecular and cellular biology 34 (23), 4232-4243, 2014 | 15 | 2014 |
| HDAC3 regulates senescence and lineage specificity in non-small cell lung cancer LJ Eichner, SD Curtis, SN Brun, JT Baumgart, DS Ross, TJ Rymoff, ... bioRxiv, 2020.10. 14.338590, 2020 | 4 | 2020 |
| KRAS INHIBITOR AND HDAC INHIBITOR COMBINATION FOR THE TREATMENT OF CANCER LJ Eichner, R Shaw US Patent App. 18/734,662, 2024 | | 2024 |
| Transcriptional repression by HDAC3 mediates T cell exclusion from Kras mutant lung tumors CK McGuire, AS Meehan, E Couser, L Bull, AC Minor, ... Proceedings of the National Academy of Sciences 121 (42), e2317694121, 2024 | | 2024 |