| Caspase-3 activation via mitochondria is required for long-term depression and AMPA receptor internalization Z Li, J Jo, JM Jia, SC Lo, DJ Whitcomb, S Jiao, K Cho, M Sheng Cell 141 (5), 859-871, 2010 | 639 | 2010 |
| Aβ1–42 inhibition of LTP is mediated by a signaling pathway involving caspase-3, Akt1 and GSK-3β J Jo, DJ Whitcomb, KM Olsen, TL Kerrigan, SC Lo, G Bru-Mercier, ... Nature neuroscience 14 (5), 545-547, 2011 | 372 | 2011 |
| Microtubule-associated protein tau is essential for long-term depression in the hippocampus T Kimura, DJ Whitcomb, J Jo, P Regan, T Piers, S Heo, C Brown, ... Philosophical Transactions of the Royal Society B: Biological Sciences 369 …, 2014 | 364 | 2014 |
| A pivotal role of GSK-3 in synaptic plasticity CA Bradley, S Peineau, C Taghibiglou, CS Nicolas, DJ Whitcomb, ... Frontiers in molecular neuroscience 5, 13, 2012 | 231 | 2012 |
| Tau phosphorylation at serine 396 residue is required for hippocampal LTD P Regan, T Piers, JH Yi, DH Kim, S Huh, SJ Park, JH Ryu, DJ Whitcomb, ... Journal of Neuroscience 35 (12), 4804-4812, 2015 | 222 | 2015 |
| Exercise improves cognitive responses to psychological stress through enhancement of epigenetic mechanisms and gene expression in the dentate gyrus A Collins, LE Hill, Y Chandramohan, D Whitcomb, SK Droste, JMHM Reul PloS one 4 (1), e4330, 2009 | 193 | 2009 |
| Acute stress causes rapid synaptic insertion of Ca2+-permeable AMPA receptors to facilitate long-term potentiation in the hippocampus G Whitehead, J Jo, EL Hogg, T Piers, DH Kim, G Seaton, H Seok, ... Brain 136 (12), 3753-3765, 2013 | 133 | 2013 |
| Regulation of synaptic Rac1 activity, long-term potentiation maintenance, and learning and memory by BCR and ABR Rac GTPase-activating proteins D Oh, S Han, J Seo, JR Lee, J Choi, J Groffen, K Kim, YS Cho, HS Choi, ... Journal of Neuroscience 30 (42), 14134-14144, 2010 | 125 | 2010 |
| Muscarinic receptors induce LTD of NMDAR EPSCs via a mechanism involving hippocalcin, AP2 and PSD-95 J Jo, GH Son, BL Winters, MJ Kim, DJ Whitcomb, BA Dickinson, YB Lee, ... Nature neuroscience 13 (10), 1216-1224, 2010 | 116 | 2010 |
| Intracellular oligomeric amyloid-beta rapidly regulates GluA1 subunit of AMPA receptor in the hippocampus DJ Whitcomb, EL Hogg, P Regan, T Piers, P Narayan, G Whitehead, ... Scientific reports 5 (1), 10934, 2015 | 111 | 2015 |
| Rare individual amyloid-β oligomers act on astrocytes to initiate neuronal damage P Narayan, KM Holmström, DH Kim, DJ Whitcomb, MR Wilson, ... Biochemistry 53 (15), 2442-2453, 2014 | 109 | 2014 |
| Translational concepts of mGluR5 in synaptic diseases of the brain TM Piers, DH Kim, BC Kim, P Regan, DJ Whitcomb, K Cho Frontiers in pharmacology 3, 199, 2012 | 92 | 2012 |
| Physiological and pathophysiological implications of synaptic tau P Regan, DJ Whitcomb, K Cho The Neuroscientist 23 (2), 137-151, 2017 | 91 | 2017 |
| TRPC6 binds to and activates calpain, independent of its channel activity, and regulates podocyte cytoskeleton, cell adhesion, and motility LK Farmer, R Rollason, DJ Whitcomb, L Ni, A Goodliff, AC Lay, ... Journal of the American Society of Nephrology 30 (10), 1910-1924, 2019 | 82 | 2019 |
| A novel mechanism of hippocampal LTD involving muscarinic receptor-triggered interactions between AMPARs, GRIP and liprin-α BA Dickinson, J Jo, H Seok, GH Son, DJ Whitcomb, CH Davies, M Sheng, ... Molecular brain 2, 1-12, 2009 | 81 | 2009 |
| SALM5 trans-synaptically interacts with LAR-RPTPs in a splicing-dependent manner to regulate synapse development Y Choi, J Nam, DJ Whitcomb, YS Song, D Kim, S Jeon, JW Um, SG Lee, ... Scientific reports 6 (1), 26676, 2016 | 77 | 2016 |
| Ca2+-permeable AMPA receptor: A new perspective on amyloid-beta mediated pathophysiology of Alzheimer's disease G Whitehead, P Regan, DJ Whitcomb, K Cho Neuropharmacology 112, 221-227, 2017 | 69 | 2017 |
| False recognition in a mouse model of Alzheimer’s disease: rescue with sensory restriction and memantine C Romberg, SM McTighe, CJ Heath, DJ Whitcomb, K Cho, TJ Bussey, ... Brain 135 (7), 2103-2114, 2012 | 63 | 2012 |
| The negative compatibility effect: A case for self-inhibition F Schlaghecken, L Rowley, S Sembi, R Simmons, D Whitcomb Advances in Cognitive Psychology 3 (1-2), 227, 2008 | 61 | 2008 |
| Adiponectin controls the apoptosis and the expression of tight junction proteins in brain endothelial cells through AdipoR1 under beta amyloid toxicity J Song, SM Choi, DJ Whitcomb, BC Kim Cell death & disease 8 (10), e3102-e3102, 2017 | 60 | 2017 |
graham collingridgeTanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Lunenfeld-TanenbaumVerified email at bris.ac.uk