| Approaches to altering particle distributions in cryo-electron microscopy sample preparation I Drulyte, RM Johnson, EL Hesketh, DL Hurdiss, CA Scarff, SA Porav, ... Acta Crystallographica Section D: Structural Biology 74 (6), 560-571, 2018 | 174 | 2018 |
| The trispecific DARPin ensovibep inhibits diverse SARS-CoV-2 variants S Rothenberger, DL Hurdiss, M Walser, F Malvezzi, J Mayor, S Ryter, ... Nature biotechnology 40 (12), 1845-1854, 2022 | 67* | 2022 |
| Evolving cryo-EM structural approaches for GPCR drug discovery X Zhang, RM Johnson, I Drulyte, L Yu, A Kotecha, R Danev, D Wootten, ... Structure 29 (9), 963-974. e6, 2021 | 60 | 2021 |
| Structural insights into the cross-neutralization of SARS-CoV and SARS-CoV-2 by the human monoclonal antibody 47D11 J Fedry, DL Hurdiss, C Wang, W Li, G Obal, I Drulyte, W Du, SC Howes, ... Science advances 7 (23), eabf5632, 2021 | 52 | 2021 |
| Sialoglycan binding triggers spike opening in a human coronavirus MF Pronker, R Creutznacher, I Drulyte, RJG Hulswit, Z Li, ... Nature 624 (7990), 201-206, 2023 | 47 | 2023 |
| An ACE2-blocking antibody confers broad neutralization and protection against Omicron and other SARS-CoV-2 variants of concern W Du, DL Hurdiss, D Drabek, AZ Mykytyn, FK Kaiser, ... Science immunology 7 (73), eabp9312, 2022 | 45 | 2022 |
| Highly potent anti-SARS-CoV-2 multi-DARPin therapeutic candidates M Walser, S Rothenberger, DL Hurdiss, A Schlegel, V Calabro, ... BioRxiv, 2020.08. 25.256339, 2020 | 38 | 2020 |
| Cryo-EM structure of coronavirus-HKU1 haemagglutinin esterase reveals architectural changes arising from prolonged circulation in humans DL Hurdiss, I Drulyte, Y Lang, TM Shamorkina, MF Pronker, ... Nature Communications 11 (1), 4646, 2020 | 36 | 2020 |
| Oral estrogen receptor PROTAC vepdegestrant (ARV-471) is highly efficacious as monotherapy and in combination with CDK4/6 or PI3K/mTOR pathway inhibitors in preclinical ER+ … SM Gough, JJ Flanagan, J Teh, M Andreoli, E Rousseau, M Pannone, ... Clinical Cancer Research 30 (16), 3549-3563, 2024 | 31 | 2024 |
| A broad-spectrum macrocyclic peptide inhibitor of the SARS-CoV-2 spike protein V Thijssen, DL Hurdiss, OJ Debski-Antoniak, MA Spence, C Franck, ... Proceedings of the National Academy of Sciences 120 (26), e2303292120, 2023 | 17 | 2023 |
| Crystal structure of the putative cyclase IdmH from the indanomycin nonribosomal peptide synthase/polyketide synthase I Drulyte, J Obajdin, CH Trinh, AP Kalverda, MW Van der Kamp, ... IUCrJ 6 (6), 1120-1133, 2019 | 13 | 2019 |
| Direct cell extraction of membrane proteins for structure–function analysis I Drulyte, AR Gutgsell, P Lloris-Garcerá, M Liss, S Geschwindner, ... Scientific Reports 13 (1), 1420, 2023 | 12 | 2023 |
| High-throughput cryo-EM epitope mapping of SARS-CoV-2 spike protein antibodies using EPU Multigrid L Drulyte, S Koester, D Lundberg, K Eng, A Malyutin, BJB Kuppeveld, ... Thermo Fisher Scientific White Paper, 2022 | 4 | 2022 |
| Neutralizing antibodies reveal cryptic vulnerabilities and interdomain crosstalk in the porcine deltacoronavirus spike protein W Du, O Debski-Antoniak, D Drabek, R van Haperen, M van Dortmondt, ... Nature Communications 15 (1), 5330, 2024 | 3 | 2024 |
| Structural basis for the inhibition of βFXIIa by garadacimab I Drulyte, R Ghai, SY Ow, EA Kapp, AJ Quek, C Panousis, MJ Wilson, ... Structure, 2024 | 2 | 2024 |
| Tomo Live: an on-the-fly reconstruction pipeline to judge data quality for cryo-electron tomography workflows M Comet, PM Dijkman, R Boer Iwema, T Franke, S Masiulis, R Schampers, ... Biological Crystallography 80 (4), 247-258, 2024 | 2 | 2024 |
| Thermo scientific™ glacios cryo-TEM: a versatile 200 kV tool for structure-based drug discovery I Drulyte, X Zhang, R Johnson, A Koh, S Masiulis, S Unger, E Pechnikova, ... Microscopy and Microanalysis 27 (S1), 3256-3258, 2021 | 2 | 2021 |
| Computational design of developable therapeutic antibodies: efficient traversal of binder landscapes and rescue of escape mutations FA Dreyer, C Schneider, A Kovaltsuk, D Cutting, MJ Byrne, DA Nissley, ... bioRxiv, 2024.10. 03.616038, 2024 | 1 | 2024 |
| A Spike Trimer Dimer–Inducing Nanobody with Anti–Sarbecovirus Activity IC Swart, OJ Debski Antoniak, A Zegar, T de Bouter, M Chatziandreou, ... bioRxiv, 2024.06. 19.598823, 2024 | | 2024 |
| Structural and Functional Studies of Polyketide Synthases I Drulyte University of Leeds, 2018 | | 2018 |
Daniel L. HurdissAssistant Professor, Utrecht UniversityVerified email at uu.nl