| Genome-wide CRISPR screens reveal host factors critical for SARS-CoV-2 infection J Wei, MM Alfajaro, PC DeWeirdt, RE Hanna, WJ Lu-Culligan, WL Cai, ... Cell 184 (1), 76-91. e13, 2021 | 501 | 2021 |
| An easy and efficient inducible CRISPR/Cas9 platform with improved specificity for multiple gene targeting J Cao, L Wu, SM Zhang, M Lu, WKC Cheung, W Cai, M Gale, Q Xu, Q Yan Nucleic acids research 44 (19), e149-e149, 2016 | 265 | 2016 |
| KDM5B promotes immune evasion by recruiting SETDB1 to silence retroelements SM Zhang, WL Cai, X Liu, D Thakral, J Luo, LH Chan, MK McGeary, ... Nature 598 (7882), 682-687, 2021 | 196 | 2021 |
| KDM5 histone demethylases repress immune response via suppression of STING L Wu, J Cao, WL Cai, SM Lang, JR Horton, DJ Jansen, ZZ Liu, JF Chen, ... PLoS biology 16 (8), e2006134, 2018 | 141 | 2018 |
| Potent BRD4 inhibitor suppresses cancer cell-macrophage interaction M Yin, Y Guo, R Hu, WL Cai, Y Li, S Pei, H Sun, C Peng, J Li, R Ye, ... Nature communications 11 (1), 1833, 2020 | 138 | 2020 |
| CECR2 drives breast cancer metastasis by promoting NF-κB signaling and macrophage-mediated immune suppression M Zhang, ZZ Liu, K Aoshima, WL Cai, H Sun, T Xu, Y Zhang, Y An, ... Science translational medicine 14 (630), eabf5473, 2022 | 86 | 2022 |
| Transcriptomic hallmarks of tumor plasticity and stromal interactions in brain metastasis E Wingrove, ZZ Liu, KD Patel, A Arnal-Estape, WL Cai, MA Melnick, ... Cell reports 27 (4), 1277-1292. e7, 2019 | 66 | 2019 |
| Mammalian SWI/SNF chromatin remodeling complexes promote tyrosine kinase inhibitor resistance in EGFR-mutant lung cancer FJ de Miguel, C Gentile, WW Feng, SJ Silva, A Sankar, F Exposito, ... Cancer Cell 41 (8), 1516-1534. e9, 2023 | 45 | 2023 |
| Multiple tumor suppressors regulate a HIF-dependent negative feedback loop via ISGF3 in human clear cell renal cancer L Liao, ZZ Liu, L Langbein, W Cai, EA Cho, J Na, X Niu, W Jiang, Z Zhong, ... Elife 7, e37925, 2018 | 42 | 2018 |
| Specific chromatin landscapes and transcription factors couple breast cancer subtype with metastatic relapse to lung or brain WL Cai, CB Greer, JF Chen, A Arnal-Estapé, J Cao, Q Yan, DX Nguyen BMC medical genomics 13, 1-18, 2020 | 32 | 2020 |
| Pharmacological disruption of mSWI/SNF complex activity restricts SARS-CoV-2 infection J Wei, A Patil, CK Collings, MM Alfajaro, Y Liang, WL Cai, MS Strine, ... Nature Genetics 55 (3), 471-483, 2023 | 26 | 2023 |
| Human WDR5 promotes breast cancer growth and metastasis via KMT2-independent translation regulation WL Cai, JFY Chen, H Chen, E Wingrove, SJ Kurley, LH Chan, M Zhang, ... Elife 11, e78163, 2022 | 19 | 2022 |
| Adaptive protein translation by the integrated stress response maintains the proliferative and migratory capacity of lung adenocarcinoma cells AE Albert, SJ Adua, WL Cai, A Arnal-Estapé, GW Cline, Z Liu, M Zhao, ... Molecular Cancer Research 17 (12), 2343-2355, 2019 | 19 | 2019 |
| Neuronal calcium sensor 1 (NCS1) promotes motility and metastatic spread of breast cancer cells in vitro and in vivo JE Apasu, D Schuette, R LaRanger, JA Steinle, LD Nguyen, ... The FASEB Journal 33 (4), 4802, 2018 | 19 | 2018 |
| Tumor progression and chromatin landscape of lung cancer are regulated by the lineage factor GATA6 A Arnal-Estapé, WL Cai, AE Albert, M Zhao, LE Stevens, F López-Giráldez, ... Oncogene 39 (18), 3726-3737, 2020 | 16 | 2020 |
| DYRK1A promotes viral entry of highly pathogenic human coronaviruses in a kinase-independent manner MS Strine, WL Cai, J Wei, MM Alfajaro, RB Filler, SB Biering, S Sarnik, ... Plos Biology 21 (6), e3002097, 2023 | 13 | 2023 |
| The KDM6A-KMT2D-p300 axis regulates susceptibility to diverse coronaviruses by mediating viral receptor expression J Wei, MM Alfajaro, WL Cai, VR Graziano, MS Strine, RB Filler, SB Biering, ... PLoS pathogens 19 (7), e1011351, 2023 | 4 | 2023 |
| Pentoxifylline induces GSK‐3β‐independent proteasomal degradation of cyclin D1 and arrests renal cancer cells in the G1 phase (616.5) W Cai, N Mastrandrea, K Tham, T Monks, S Lau The FASEB Journal 28, 616.5, 2014 | 4 | 2014 |
| Facts and hopes in using omics to advance combined immunotherapy strategies RC Augustin, WL Cai, JJ Luke, R Bao Clinical Cancer Research 30 (9), 1724-1732, 2024 | 2 | 2024 |
| Peer teaching as bioinformatics training strategy: incentives, challenges, and benefits NT Rahman, C Meyer, D Thakral, WL Cai, AT Chen, R Obaid, ... Medical Reference Services Quarterly 41 (1), 13-25, 2022 | 2 | 2022 |
Qin YanYale School of MedicineVerified email at yale.edu
