| Architecture and selectivity in aquaporins: 2.5 Å X-ray structure of aquaporin Z DF Savage, PF Egea, Y Robles-Colmenares, JDOC III, RM Stroud PLoS biology 1 (3), e72, 2003 | 361 | 2003 |
| Substrate twinning activates the signal recognition particle and its receptor PF Egea, S Shan, J Napetschnig, DF Savage, P Walter, RM Stroud Nature 427 (6971), 215-221, 2004 | 355 | 2004 |
| Spatially ordered dynamics of the bacterial carbon fixation machinery DF Savage, B Afonso, AH Chen, PA Silver Science 327 (5970), 1258-1261, 2010 | 352 | 2010 |
| Modularity of a carbon-fixing protein organelle W Bonacci, PK Teng, B Afonso, H Niederholtmeyer, P Grob, PA Silver, ... Proceedings of the National Academy of Sciences 109 (2), 478-483, 2012 | 315 | 2012 |
| Engineering cyanobacteria to synthesize and export hydrophilic products H Niederholtmeyer, BT Wolfstädter, DF Savage, PA Silver, JC Way Applied and environmental microbiology 76 (11), 3462-3466, 2010 | 302 | 2010 |
| Circularly permuted and PAM-modified Cas9 variants broaden the targeting scope of base editors TP Huang, KT Zhao, SM Miller, NM Gaudelli, BL Oakes, C Fellmann, ... Nature biotechnology 37 (6), 626-631, 2019 | 278 | 2019 |
| pH determines the energetic efficiency of the cyanobacterial CO2 concentrating mechanism NM Mangan, A Flamholz, RD Hood, R Milo, DF Savage Proceedings of the National Academy of Sciences 113 (36), E5354-E5362, 2016 | 227 | 2016 |
| Profiling of engineering hotspots identifies an allosteric CRISPR-Cas9 switch BL Oakes, DC Nadler, A Flamholz, C Fellmann, BT Staahl, JA Doudna, ... Nature biotechnology 34 (6), 646-651, 2016 | 227 | 2016 |
| Revisiting trade-offs between Rubisco kinetic parameters AI Flamholz, N Prywes, U Moran, D Davidi, YM Bar-On, LM Oltrogge, ... Biochemistry 58 (31), 3365-3376, 2019 | 204 | 2019 |
| Accelerated RNA detection using tandem CRISPR nucleases TY Liu, GJ Knott, DCJ Smock, JJ Desmarais, S Son, A Bhuiya, ... Nature chemical biology 17 (9), 982-988, 2021 | 195 | 2021 |
| Controlling CRISPR-Cas9 with ligand-activated and ligand-deactivated sgRNAs K Kundert, JE Lucas, KE Watters, C Fellmann, AH Ng, BM Heineike, ... Nature communications 10 (1), 2127, 2019 | 188 | 2019 |
| Structural basis of aquaporin inhibition by mercury DF Savage, RM Stroud Journal of molecular biology 368 (3), 607-617, 2007 | 185 | 2007 |
| A general protocol for the crystallization of membrane proteins for X-ray structural investigation ZER Newby, JD O'Connell III, F Gruswitz, FA Hays, WEC Harries, ... Nature protocols 4 (5), 619-637, 2009 | 179 | 2009 |
| Catalysis, specificity, and ACP docking site of Streptomyces coelicolor malonyl-CoA: ACP transacylase AT Keatinge-Clay, AA Shelat, DF Savage, SC Tsai, LJW Miercke, ... Structure 11 (2), 147-154, 2003 | 178 | 2003 |
| Structure of the complex I-like molecule NDH of oxygenic photosynthesis TG Laughlin, AN Bayne, JF Trempe, DF Savage, KM Davies Nature 566 (7744), 411-414, 2019 | 153 | 2019 |
| Defossiling fuel: how synthetic biology can transform biofuel production DF Savage, J Way, PA Silver ACS Chemical Biology 3 (1), 13-16, 2008 | 153 | 2008 |
| An open-hardware platform for optogenetics and photobiology KP Gerhardt, EJ Olson, SM Castillo-Hair, LA Hartsough, BP Landry, ... Scientific reports 6 (1), 35363, 2016 | 147 | 2016 |
| The bacterial carbon-fixing organelle is formed by shell envelopment of preassembled cargo AH Chen, A Robinson-Mosher, DF Savage, PA Silver, JK Polka PloS one 8 (9), e76127, 2013 | 141 | 2013 |
| Multivalent interactions between CsoS2 and Rubisco mediate α-carboxysome formation LM Oltrogge, T Chaijarasphong, AW Chen, ER Bolin, S Marqusee, ... Nature structural & molecular biology 27 (3), 281-287, 2020 | 136 | 2020 |
| Rapid construction of metabolite biosensors using domain-insertion profiling DC Nadler, SA Morgan, A Flamholz, KE Kortright, DF Savage Nature communications 7 (1), 12266, 2016 | 125 | 2016 |
Avi FlamholzCalifornia Institute of TechnologyVerified email at caltech.edu
