Inhibition of Cytochromes P-450 and Induction of Glutathione S-Transferases by Sulforaphane in Primary Human and Rat Hepatocytes K Mahéo, F Morel, S Langouët, H Kramer, E Le Ferrec, B Ketterer, ... Cancer Research 57 (17), 3649-3652, 1997 | 335 | 1997 |
In Vitro Models of the Intestinal Barrier: The Report and Recommendations of ECVAM Workshop 46, E Le Ferrec, C Chesne, P Artusson, D Brayden, G Fabre, P Gires, ... Alternatives to laboratory animals 29 (6), 649-668, 2001 | 321 | 2001 |
Analysis of drug transporter expression in human intestinal Caco‐2 cells by real‐time PCR N Maubon, M Le Vee, L Fossati, M Audry, E Le Ferrec, S Bolze, O Fardel Fundamental & clinical pharmacology 21 (6), 659-663, 2007 | 210 | 2007 |
Polycyclic aromatic hydrocarbons inhibit differentiation of human monocytes into macrophages J van Grevenynghe, S Rion, E Le Ferrec, M Le Vee, L Amiot, R Fauchet, ... The Journal of Immunology 170 (5), 2374-2381, 2003 | 197 | 2003 |
The human glutathione transferase alpha locus: genomic organization of the gene cluster and functional characterization of the genetic polymorphism in the hGSTA1 promoter F Morel, C Rauch, B Coles, E Le Ferrec, A Guillouzo Pharmacogenetics and Genomics 12 (4), 277-286, 2002 | 170 | 2002 |
Interleukin-8 induction by the environmental contaminant benzo (a) pyrene is aryl hydrocarbon receptor-dependent and leads to lung inflammation N Podechard, V Lecureur, E Le Ferrec, I Guenon, L Sparfel, D Gilot, ... Toxicology letters 177 (2), 130-137, 2008 | 150 | 2008 |
Polycyclic aromatic hydrocarbons affect functional differentiation and maturation of human monocyte-derived dendritic cells B Laupeze, L Amiot, L Sparfel, E Le Ferrec, R Fauchet, O Fardel The Journal of Immunology 168 (6), 2652-2658, 2002 | 149 | 2002 |
ERK-dependent induction of TNFα expression by the environmental contaminant benzo (a) pyrene in primary human macrophages V Lecureur, E Le Ferrec, M N’diaye, M Le Vee, C Gardyn, D Gilot, ... FEBS letters 579 (9), 1904-1910, 2005 | 132 | 2005 |
Aryl hydrocarbon receptor-and calcium-dependent induction of the chemokine CCL1 by the environmental contaminant benzo [a] pyrene M N'Diaye, E Le Ferrec, D Lagadic-Gossmann, S Corre, D Gilot, ... Journal of Biological Chemistry 281 (29), 19906-19915, 2006 | 130 | 2006 |
Microalgal carotenoids and phytosterols regulate biochemical mechanisms involved in human health and disease prevention M Le Goff, E Le Ferrec, C Mayer, V Mimouni, D Lagadic-Gossmann, ... Biochimie 167, 106-118, 2019 | 94 | 2019 |
Transcriptional induction of CYP1A1 by oltipraz in human Caco-2 cells is aryl hydrocarbon receptor-and calcium-dependent E Le Ferrec, D Lagadic-Gossmann, C Rauch, C Bardiau, K Maheo, ... Journal of Biological Chemistry 277 (27), 24780-24787, 2002 | 86 | 2002 |
Dioxin-mediated up-regulation of aryl hydrocarbon receptor target genes is dependent on the calcium/calmodulin/CaMKIα pathway P Monteiro, D Gilot, E Le Ferrec, C Rauch, D Lagadic-Gossmann, ... Molecular Pharmacology 73 (3), 769-777, 2008 | 82 | 2008 |
Induction of intracellular calcium concentration by environmental benzo (a) pyrene involves a β2-adrenergic receptor/adenylyl cyclase/Epac-1/inositol 1, 4, 5-trisphosphate … A Mayati, N Levoin, H Paris, M N'Diaye, A Courtois, P Uriac, ... Journal of Biological Chemistry 287 (6), 4041-4052, 2012 | 79 | 2012 |
Lipophilic components of diesel exhaust particles induce pro-inflammatory responses in human endothelial cells through AhR dependent pathway (s) BC Brinchmann, T Skuland, MH Rambøl, K Szoke, JE Brinchmann, ... Particle and fibre toxicology 15, 1-17, 2018 | 63 | 2018 |
AhR-and c-maf-dependent induction of β7-integrin expression in human macrophages in response to environmental polycyclic aromatic hydrocarbons P Monteiro, D Gilot, E Le Ferrec, V Lecureur, M N’diaye, M Le Vee, ... Biochemical and biophysical research communications 358 (2), 442-448, 2007 | 46 | 2007 |
Differential regulation of multidrug resistance-associated protein 2 (MRP2) and cytochromes P450 2B1/2 and 3A1/2 in phenobarbital-treated hepatocytes A Courtois, L Payen, E Le Ferrec, GL Scheffer, Y Trinquart, A Guillouzo, ... Biochemical pharmacology 63 (2), 333-341, 2002 | 46 | 2002 |
NPC1 repression contributes to lipid accumulation in human macrophages exposed to environmental aryl hydrocarbons N Podechard, E Le Ferrec, A Rebillard, O Fardel, V Lecureur Cardiovascular research 82 (2), 361-370, 2009 | 44 | 2009 |
Lung cancer associated with combustion particles and fine particulate matter (PM2. 5)-The roles of polycyclic aromatic hydrocarbons (PAHs) and the aryl hydrocarbon receptor (AhR) JA Holme, J Vondráček, M Machala, D Lagadic-Gossmann, CFA Vogel, ... Biochemical pharmacology, 115801, 2023 | 38 | 2023 |
Benzo [a] pyrene-induced DNA damage associated with mutagenesis in primary human activated T lymphocytes M Liamin, E Boutet-Robinet, EL Jamin, M Fernier, L Khoury, B Kopp, ... Biochemical pharmacology 137, 113-124, 2017 | 35 | 2017 |
Calcium signaling and β2-adrenergic receptors regulate 1-nitropyrene induced CXCL8 responses in BEAS-2B cells A Mayati, E Le Ferrec, JA Holme, O Fardel, D Lagadic-Gossmann, ... Toxicology in Vitro 28 (6), 1153-1157, 2014 | 35 | 2014 |