| Activation of sphingosine kinase 1 by ERK1/2‐mediated phosphorylation SM Pitson, PAB Moretti, JR Zebol, HE Lynn, P Xia, MA Vadas, ... The EMBO journal, 2003 | 663 | 2003 |
| An oncogenic role of sphingosine kinase P Xia, JR Gamble, L Wang, SM Pitson, PAB Moretti, BW Wattenberg, ... Current Biology 10 (23), 1527-1530, 2000 | 540 | 2000 |
| The role of the extracellular matrix and its molecular and cellular regulators in cancer cell plasticity V Poltavets, M Kochetkova, SM Pitson, MS Samuel Frontiers in oncology 8, 431, 2018 | 387 | 2018 |
| Sphingosine kinase interacts with TRAF2 and dissects tumor necrosis factor-α signaling P Xia, L Wang, PAB Moretti, N Albanese, F Chai, SM Pitson, RJ D'Andrea, ... Journal of Biological Chemistry 277 (10), 7996-8003, 2002 | 380 | 2002 |
| Regulation of sphingosine kinase and sphingolipid signaling SM Pitson Trends in biochemical sciences 36 (2), 97-107, 2011 | 374 | 2011 |
| Phosphorylation-dependent translocation of sphingosine kinase to the plasma membrane drives its oncogenic signalling SM Pitson, P Xia, TM Leclercq, PAB Moretti, JR Zebol, HE Lynn, ... The Journal of experimental medicine 201 (1), 49-54, 2005 | 338 | 2005 |
| FTY720 and (S)-FTY720 vinylphosphonate inhibit sphingosine kinase 1 and promote its proteasomal degradation in human pulmonary artery smooth muscle, breast cancer and androgen … F Tonelli, KG Lim, C Loveridge, J Long, SM Pitson, G Tigyi, R Bittman, ... Cellular signalling 22 (10), 1536-1542, 2010 | 230 | 2010 |
| Expression of a catalytically inactive sphingosine kinase mutant blocks agonist-induced sphingosine kinase activation: a dominant-negative sphingosine kinase SM Pitson, PAB Moretti, JR Zebol, P Xia, JR Gamble, MA Vadas, ... Journal of Biological Chemistry 275 (43), 33945-33950, 2000 | 227 | 2000 |
| Essential roles of sphingosine‐1‐phosphate and platelet‐derived growth factor in the maintenance of human embryonic stem cells A Pébay, RCB Wong, SM Pitson, EJ Wolvetang, GSL Peh, A Filipczyk, ... Stem Cells 23 (10), 1541-1548, 2005 | 218 | 2005 |
| Human sphingosine kinase: purification, molecular cloning and characterization of the native and recombinant enzymes SM PITSON, R J. D'ANDREA, L VANDELEUR, PAB MORETTI, P XIA, ... Biochemical Journal 350 (2), 429-441, 2000 | 216 | 2000 |
| Roles, regulation and inhibitors of sphingosine kinase 2 HA Neubauer, SM Pitson The FEBS journal 280 (21), 5317-5336, 2013 | 194 | 2013 |
| Sphingosine kinase transmits estrogen signaling in human breast cancer cells OA Sukocheva, L Wang, N Albanese, SM Pitson, MA Vadas, P Xia Molecular endocrinology 17 (10), 2002-2012, 2003 | 193 | 2003 |
| Translocation of sphingosine kinase 1 to the plasma membrane is mediated by calcium-and integrin-binding protein 1 KE Jarman, PAB Moretti, JR Zebol, SM Pitson Journal of Biological Chemistry 285 (1), 483-492, 2010 | 187 | 2010 |
| Sphingosine kinase modulates microvascular tone and myogenic responses through activation of RhoA/Rho kinase SS Bolz, L Vogel, D Sollinger, R Derwand, C Boer, SM Pitson, S Spiegel, ... Circulation 108 (3), 342-347, 2003 | 170 | 2003 |
| Overexpression of sphingosine kinase 1 prevents ceramide accumulation and ameliorates muscle insulin resistance in high-fat diet–fed mice CR Bruce, S Risis, JR Babb, C Yang, GM Kowalski, A Selathurai, ... Diabetes 61 (12), 3148-3155, 2012 | 165 | 2012 |
| Sphingosine-1-phosphate facilitates trafficking of hematopoietic stem cells and their mobilization by CXCR4 antagonists in mice JG Juarez, N Harun, M Thien, R Welschinger, R Baraz, A Dela Pena, ... Blood, the Journal of the American Society of Hematology 119 (3), 707-716, 2012 | 162 | 2012 |
| Regulation of the hepatitis C virus RNA replicase by endogenous lipid peroxidation D Yamane, DR McGivern, E Wauthier, MK Yi, VJ Madden, C Welsch, ... Nature medicine 20 (8), 927-935, 2014 | 161 | 2014 |
| The sphingosine and diacylglycerol kinase superfamily of signaling kinases: localization as a key to signaling function BW Wattenberg, SM Pitson, DM Raben Journal of lipid research 47 (6), 1128-1139, 2006 | 161 | 2006 |
| Reduced sphingosine kinase-1 and enhanced sphingosine 1-phosphate lyase expression demonstrate deregulated sphingosine 1-phosphate signaling in Alzheimer’s disease J Ceccom, N Loukh, V Lauwers-Cances, C Touriol, Y Nicaise, C Gentil, ... Acta neuropathologica communications 2, 1-10, 2014 | 156 | 2014 |
| The sphingosine kinase 1 inhibitor 2-(p-hydroxyanilino)-4-(p-chlorophenyl) thiazole induces proteasomal degradation of sphingosine kinase 1 in mammalian cells C Loveridge, F Tonelli, T Leclercq, KG Lim, JS Long, E Berdyshev, ... Journal of Biological Chemistry 285 (50), 38841-38852, 2010 | 146 | 2010 |
