Pseudouridinylation of mRNA coding sequences alters translation DE Eyler, MK Franco, Z Batool, MZ Wu, ML Dubuke, M Dobosz-Bartoszek, ... Proceedings of the National Academy of Sciences 116 (46), 23068-23074, 2019 | 197 | 2019 |
Ribosomes slide on lysine-encoding homopolymeric A stretches KS Koutmou, AP Schuller, JL Brunelle, A Radhakrishnan, S Djuranovic, ... Elife 4, e05534, 2015 | 142 | 2015 |
Translational control by lysine-encoding A-rich sequences LL Arthur, S Pavlovic-Djuranovic, KS Koutmou, R Green, P Szczesny, ... Science advances 1 (6), e1500154, 2015 | 126 | 2015 |
Identification and Quantification of Modified Nucleosides in Saccharomyces cerevisiae mRNAs M Tardu, JD Jones, RT Kennedy, Q Lin, KS Koutmou ACS chemical biology 14 (7), 1403-1409, 2019 | 93 | 2019 |
Systemic RNA interference deficiency-1 (SID-1) extracellular domain selectively binds long double-stranded RNA and is required for RNA transport by SID-1 W Li, KS Koutmou, DJ Leahy, M Li Journal of Biological Chemistry 290 (31), 18904-18913, 2015 | 69 | 2015 |
A molecular‐level perspective on the frequency, distribution, and consequences of messenger RNA modifications JD Jones, J Monroe, KS Koutmou Wiley Interdisciplinary Reviews: RNA 11 (4), e1586, 2020 | 61 | 2020 |
RF3: GTP promotes rapid dissociation of the class 1 termination factor KS Koutmou, ME McDonald, JL Brunelle, R Green Rna 20 (5), 609-620, 2014 | 58 | 2014 |
Protein–precursor tRNA contact leads to sequence-specific recognition of 5′ leaders by bacterial ribonuclease P KS Koutmou, NH Zahler, JC Kurz, FE Campbell, ME Harris, CA Fierke Journal of molecular biology 396 (1), 195-208, 2010 | 55 | 2010 |
Importance of RNA‐protein interactions in bacterial ribonuclease P structure and catalysis JK Smith, J Hsieh, CA Fierke Biopolymers: Original Research on Biomolecules 87 (5‐6), 329-338, 2007 | 54 | 2007 |
A Divalent Cation Stabilizes the Active Conformation of the B. subtilis RNase P· Pre-tRNA Complex: A Role for an Inner-Sphere Metal Ion in RNase P J Hsieh, KS Koutmou, D Rueda, M Koutmos, NG Walter, CA Fierke Journal of molecular biology 400 (1), 38-51, 2010 | 45 | 2010 |
Pseudouridine synthase 7 is an opportunistic enzyme that binds and modifies substrates with diverse sequences and structures MK Purchal, DE Eyler, M Tardu, MK Franco, MM Korn, T Khan, ... Proceedings of the National Academy of Sciences 119 (4), e2109708119, 2022 | 38 | 2022 |
NMR and XAS reveal an inner-sphere metal binding site in the P4 helix of the metallo-ribozyme ribonuclease P KS Koutmou, A Casiano-Negroni, MM Getz, S Pazicni, AJ Andrews, ... Proceedings of the National Academy of Sciences 107 (6), 2479-2484, 2010 | 36 | 2010 |
Chemical modifications to mRNA nucleobases impact translation elongation and termination MK Franco, KS Koutmou Biophysical chemistry 285, 106780, 2022 | 29 | 2022 |
CGG repeats trigger translational frameshifts that generate aggregation-prone chimeric proteins SE Wright, CM Rodriguez, J Monroe, J Xing, A Krans, BN Flores, V Barsur, ... Nucleic acids research 50 (15), 8674-8689, 2022 | 23 | 2022 |
Synthesis at the speed of codons KS Koutmou, A Radhakrishnan, R Green Trends in biochemical sciences 40 (12), 717-718, 2015 | 23 | 2015 |
The RNR motif of B. subtilis RNase P protein interacts with both PRNA and pre-tRNA to stabilize an active conformer KS Koutmou, JJ Day-Storms, CA Fierke RNA 17 (7), 1225-1235, 2011 | 21 | 2011 |
Sequence-specific capture and concentration of viral RNA by type III CRISPR system enhances diagnostic A Nemudraia, A Nemudryi, M Buyukyoruk, AM Scherffius, T Zahl, ... Nature Communications 13 (1), 7762, 2022 | 18 | 2022 |
Methylated guanosine and uridine modifications in S. cerevisiae mRNAs modulate translation elongation JD Jones, MK Franco, TJ Smith, LR Snyder, AG Anders, BT Ruotolo, ... RSC Chemical Biology 4 (5), 363-378, 2023 | 16 | 2023 |
Anticodon stem-loop tRNA modifications influence codon decoding and frame maintenance during translation TJ Smith, RN Giles, KS Koutmou Seminars in Cell & Developmental Biology 154, 105-113, 2024 | 13 | 2024 |
The cAMP signaling pathway regulates Epe1 protein levels and heterochromatin assembly K Bao, CM Shan, X Chen, G Raiymbek, JG Monroe, Y Fang, T Toda, ... PLoS genetics 18 (2), e1010049, 2022 | 13 | 2022 |