Articles with public access mandates - David BarfordLearn more
Not available anywhere: 10
Activation of Rho GTPases by DOCK exchange factors is mediated by a nucleotide sensor
J Yang, Z Zhang, SM Roe, CJ Marshall, D Barford
Science 325 (5946), 1398-1402, 2009
Mandates: Cancer Research UK
Insights into the anaphase-promoting complex: a molecular machine that regulates mitosis
L Chang, D Barford
Current opinion in structural biology 29, 1-9, 2014
Mandates: Cancer Research UK, UK Medical Research Council
Recombinant expression, reconstitution and structure of human anaphase-promoting complex (APC/C)
Z Zhang, J Yang, EH Kong, WCH Chao, EP Morris, PCA da Fonseca, ...
Biochemical Journal 449 (2), 365-371, 2013
Mandates: Cancer Research UK
Structural interconversions of the anaphase-promoting complex/cyclosome (APC/C) regulate cell cycle transitions
D Barford
Current opinion in structural biology 61, 86-97, 2020
Mandates: Cancer Research UK, UK Medical Research Council, UK Research & Innovation
The Structure of Tap42/α4 Reveals a Tetratricopeptide Repeat-like Fold and Provides Insights into PP2A Regulation,
J Yang, SM Roe, TD Prickett, DL Brautigan, D Barford
Biochemistry 46 (30), 8807-8815, 2007
Mandates: Cancer Research UK
Molecular structure of the N-terminal domain of the APC/C subunit Cdc27 reveals a homo-dimeric tetratricopeptide repeat architecture
Z Zhang, SM Roe, M Diogon, E Kong, H El Alaoui, D Barford
Journal of molecular biology 397 (5), 1316-1328, 2010
Mandates: Cancer Research UK
The potential of cryo-electron microscopy for structure-based drug design
A Boland, L Chang, D Barford
Essays in biochemistry 61 (5), 543-560, 2017
Mandates: Cancer Research UK, UK Medical Research Council, European Commission
Conserved and divergent mechanisms of inner kinetochore assembly onto centromeric chromatin
S Yatskevich, D Barford, KW Muir
Current Opinion in Structural Biology 81, 102638, 2023
Mandates: Cancer Research UK, UK Medical Research Council, UK Research & Innovation
Methods for preparing crystals of reversibly oxidized proteins: crystallization of protein tyrosine phosphatase 1B as an example
A Salmeen, D Barford
Redox-Mediated Signal Transduction: Methods and Protocols, 97-112, 2009
Mandates: Cancer Research UK
Methods for preparing Cryo-EM grids of large macromolecular complexes
L Chang, D Barford
The Ubiquitin Proteasome System: Methods and Protocols, 209-215, 2018
Mandates: Cancer Research UK, UK Medical Research Council, UK Research & Innovation
Available somewhere: 73
Molecular discrimination of structurally equivalent Lys 63‐linked and linear polyubiquitin chains
D Komander, F Reyes‐Turcu, JDF Licchesi, P Odenwaelder, ...
EMBO reports 10 (5), 466-473, 2009
Mandates: US National Institutes of Health, Cancer Research UK
Structure of the mitotic checkpoint complex
WCH Chao, K Kulkarni, Z Zhang, EH Kong, D Barford
Nature 484 (7393), 208-213, 2012
Mandates: Cancer Research UK
The structure of the CYLD USP domain explains its specificity for Lys63-linked polyubiquitin and reveals a B box module
D Komander, CJ Lord, H Scheel, S Swift, K Hofmann, A Ashworth, ...
Molecular cell 29 (4), 451-464, 2008
Mandates: Cancer Research UK
A Raf-induced allosteric transition of KSR stimulates phosphorylation of MEK
DF Brennan, AC Dar, NT Hertz, WCH Chao, AL Burlingame, KM Shokat, ...
Nature 472 (7343), 366-369, 2011
Mandates: US National Institutes of Health, Howard Hughes Medical Institute, Cancer …
Atomic structure of the APC/C and its mechanism of protein ubiquitination
L Chang, Z Zhang, J Yang, SH McLaughlin, D Barford
Nature 522 (7557), 450-454, 2015
Mandates: Cancer Research UK, UK Medical Research Council
Molecular basis of APC/C regulation by the spindle assembly checkpoint
C Alfieri, L Chang, Z Zhang, J Yang, S Maslen, M Skehel, D Barford
Nature 536 (7617), 431-436, 2016
Mandates: Cancer Research UK, UK Medical Research Council, UK Research & Innovation
Molecular architecture and mechanism of the anaphase-promoting complex
L Chang, Z Zhang, J Yang, SH McLaughlin, D Barford
Nature 513 (7518), 388-393, 2014
Mandates: Cancer Research UK, UK Medical Research Council, UK Research & Innovation
Structures of APC/CCdh1 with substrates identify Cdh1 and Apc10 as the D-box co-receptor
PCA da Fonseca, EH Kong, Z Zhang, A Schreiber, MA Williams, EP Morris, ...
Nature 470 (7333), 274-278, 2011
Mandates: Cancer Research UK
Molecular mechanism of APC/C activation by mitotic phosphorylation
S Zhang, L Chang, C Alfieri, Z Zhang, J Yang, S Maslen, M Skehel, ...
Nature 533 (7602), 260-264, 2016
Mandates: Bill & Melinda Gates Foundation, Cancer Research UK, UK Medical Research …
Mechanism of farnesylated CAAX protein processing by the intramembrane protease Rce1
I Manolaridis, K Kulkarni, RB Dodd, S Ogasawara, Z Zhang, G Bineva, ...
Nature 504 (7479), 301-305, 2013
Mandates: UK Biotechnology and Biological Sciences Research Council, Cancer Research …
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