| Double-lanthanide-binding tags: design, photophysical properties, and NMR applications LJ Martin, MJ Hähnke, M Nitz, J Wöhnert, NR Silvaggi, KN Allen, ... Journal of the American Chemical Society 129 (22), 7106-7113, 2007 | 179 | 2007 |
| Structures of Clostridium botulinum Neurotoxin Serotype A Light Chain complexed with small-molecule inhibitors highlight active-site flexibility NR Silvaggi, GE Boldt, MS Hixon, JP Kennedy, S Tzipori, KD Janda, ... Chemistry & biology 14 (5), 533-542, 2007 | 157 | 2007 |
| A 1.2-Å snapshot of the final step of bacterial cell wall biosynthesis W Lee, MA McDonough, LP Kotra, ZH Li, NR Silvaggi, Y Takeda, JA Kelly, ... Proceedings of the National Academy of Sciences 98 (4), 1427-1431, 2001 | 149 | 2001 |
| Molecular basis for ADP-ribose binding to the Mac1 domain of SARS-CoV-2 nsp3 DN Frick, RS Virdi, N Vuksanovic, N Dahal, NR Silvaggi Biochemistry 59 (28), 2608-2615, 2020 | 109 | 2020 |
| Structures of two kinetic intermediates reveal species specificity of penicillin-binding proteins MA McDonough, JW Anderson, NR Silvaggi, RF Pratt, JR Knox, JA Kelly Journal of molecular biology 322 (1), 111-122, 2002 | 109 | 2002 |
| Double-lanthanide-binding tags for macromolecular crystallographic structure determination NR Silvaggi, LJ Martin, H Schwalbe, B Imperiali, KN Allen Journal of the American Chemical Society 129 (22), 7114-7120, 2007 | 94 | 2007 |
| The X-ray crystal structures of human α-phosphomannomutase 1 reveal the structural basis of congenital disorder of glycosylation type 1a NR Silvaggi, C Zhang, Z Lu, J Dai, D Dunaway-Mariano, KN Allen Journal of Biological Chemistry 281 (21), 14918-14926, 2006 | 84 | 2006 |
| Catalytic features of the botulinum neurotoxin A light chain revealed by high resolution structure of an inhibitory peptide complex NR Silvaggi, D Wilson, S Tzipori, KN Allen Biochemistry 47 (21), 5736-5745, 2008 | 78 | 2008 |
| The Crystal Structure of Phosphonate-Inhibited d-Ala-d-Ala Peptidase Reveals an Analogue of a Tetrahedral Transition State, NR Silvaggi, JW Anderson, SR Brinsmade, RF Pratt, JA Kelly Biochemistry 42 (5), 1199-1208, 2003 | 72 | 2003 |
| Evaluation of adamantane hydroxamates as botulinum neurotoxin inhibitors: synthesis, crystallography, modeling, kinetic and cellular based studies P Šilhár, NR Silvaggi, S Pellett, K Čapková, EA Johnson, KN Allen, ... Bioorganic & medicinal chemistry 21 (5), 1344-1348, 2013 | 66 | 2013 |
| Crystal structures of complexes between the R61 DD-peptidase and peptidoglycan-mimetic β-lactams: a non-covalent complex with a “perfect penicillin” NR Silvaggi, HR Josephine, AP Kuzin, R Nagarajan, RF Pratt, JA Kelly Journal of molecular biology 345 (3), 521-533, 2005 | 66 | 2005 |
| Streptomyces wadayamensis MppP Is a Pyridoxal 5′-Phosphate-Dependent l-Arginine α-Deaminase, γ-Hydroxylase in the Enduracididine Biosynthetic Pathway L Han, AW Schwabacher, GR Moran, NR Silvaggi Biochemistry 54 (47), 7029-7040, 2015 | 53 | 2015 |
| You are lost without a map: Navigating the sea of protein structures AL Lamb, TJ Kappock, NR Silvaggi Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1854 (4), 258-268, 2015 | 45 | 2015 |
| Periplasmic Cytophaga hutchinsonii endoglucanases are required for use of crystalline cellulose as the sole source of carbon and energy Y Zhu, L Han, KL Hefferon, NR Silvaggi, DB Wilson, MJ McBride Applied and environmental microbiology 82 (15), 4835-4845, 2016 | 44 | 2016 |
| Structural and Functional Characterization of MppR, an Enduracididine Biosynthetic Enzyme from Streptomyces hygroscopicus: Functional Diversity in the … AM Burroughs, RW Hoppe, NC Goebel, BH Sayyed, TJ Voegtline, ... Biochemistry 52 (26), 4492-4506, 2013 | 44 | 2013 |
| Inactivation of Bacterial dd-Peptidase by β-Sultams A Llinás, N Ahmed, M Cordaro, AP Laws, JM Frere, M Delmarcelle, ... Biochemistry 44 (21), 7738-7746, 2005 | 39 | 2005 |
| Chirality holds the key for potent inhibition of the botulinum neurotoxin serotype a protease GN Stowe, P Šilhár, MS Hixon, NR Silvaggi, KN Allen, ST Moe, ... Organic letters 12 (4), 756-759, 2010 | 36 | 2010 |
| Streptomyces wadayamensis MppP is a PLP-Dependent Oxidase, Not an Oxygenase L Han, N Vuksanovic, SA Oehm, TG Fenske, AW Schwabacher, ... Biochemistry 57 (23), 3252-3264, 2018 | 35 | 2018 |
| Discovery of drug-like ligands for the Mac1 domain of SARS-CoV-2 Nsp3 RS Virdi, RV Bavisotto, NC Hopper, N Vuksanovic, TR Melkonian, ... SLAS DISCOVERY: Advancing the Science of Drug Discovery 25 (10), 1162-1170, 2020 | 33 | 2020 |
| RitR is an archetype for a novel family of redox sensors in the streptococci that has evolved from two-component response regulators and is required for pneumococcal colonization DG Glanville, L Han, AF Maule, A Woodacre, D Thanki, IT Abdullah, ... PLoS pathogens 14 (5), e1007052, 2018 | 33 | 2018 |
Karen N. AllenChair and Professor, Department of Chemistry, Boston UniversityVerified email at bu.edu
