| The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance B Vandanmagsar, YH Youm, A Ravussin, JE Galgani, K Stadler, ... Nature medicine 17 (2), 179-188, 2011 | 2905 | 2011 |
| The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome–mediated inflammatory disease YH Youm, KY Nguyen, RW Grant, EL Goldberg, M Bodogai, D Kim, ... Nature medicine 21 (3), 263-269, 2015 | 2009 | 2015 |
| Canonical Nlrp3 inflammasome links systemic low-grade inflammation to functional decline in aging YH Youm, RW Grant, LR McCabe, DC Albarado, KY Nguyen, A Ravussin, ... Cell metabolism 18 (4), 519-532, 2013 | 654 | 2013 |
| Obesity increases the production of proinflammatory mediators from adipose tissue T cells and compromises TCR repertoire diversity: implications for systemic inflammation and … H Yang, YH Youm, B Vandanmagsar, A Ravussin, JM Gimble, ... The Journal of Immunology 185 (3), 1836-1845, 2010 | 537 | 2010 |
| Inflammasome-driven catecholamine catabolism in macrophages blunts lipolysis during ageing CD Camell, J Sander, O Spadaro, A Lee, KY Nguyen, A Wing, ... Nature 550 (7674), 119-123, 2017 | 416 | 2017 |
| Obesity accelerates thymic aging H Yang, YH Youm, B Vandanmagsar, J Rood, KG Kumar, AA Butler, ... Blood, The Journal of the American Society of Hematology 114 (18), 3803-3812, 2009 | 366 | 2009 |
| Ghrelin promotes thymopoiesis during aging VD Dixit, H Yang, Y Sun, AT Weeraratna, YH Youm, RG Smith, DD Taub The Journal of clinical investigation 117 (10), 2778-2790, 2007 | 263 | 2007 |
| Inhibition of thymic adipogenesis by caloric restriction is coupled with reduction in age-related thymic involution H Yang, YH Youm, VD Dixit The Journal of Immunology 183 (5), 3040-3052, 2009 | 213 | 2009 |
| Caloric restriction in humans reveals immunometabolic regulators of health span O Spadaro, Y Youm, I Shchukina, S Ryu, S Sidorov, A Ravussin, ... Science 375 (6581), 671-677, 2022 | 208 | 2022 |
| Elimination of the NLRP3-ASC inflammasome protects against chronic obesity-induced pancreatic damage YH Youm, A Adijiang, B Vandanmagsar, D Burk, A Ravussin, VD Dixit Endocrinology 152 (11), 4039-4045, 2011 | 194 | 2011 |
| IGF1 shapes macrophage activation in response to immunometabolic challenge O Spadaro, CD Camell, L Bosurgi, KY Nguyen, YH Youm, CV Rothlin, ... Cell reports 19 (2), 225-234, 2017 | 190 | 2017 |
| Biomechanical analyses of forearm pronation-supination and elbow flexion-extension Y Youm, RF Dryer, K Thambyrajah, AE Flatt, BL Sprague Journal of Biomechanics 12 (4), 245-255, 1979 | 185 | 1979 |
| Less keratinocyte-derived factors related to more keratinocyte apoptosis in depigmented than normally pigmented suction-blistered epidermis may cause passive melanocyte death … AY Lee, NH Kim, WI Choi, YH Youm Journal of investigative dermatology 124 (5), 976-983, 2005 | 182 | 2005 |
| Aging induces an Nlrp3 inflammasome-dependent expansion of adipose B cells that impairs metabolic homeostasis CD Camell, P Günther, A Lee, EL Goldberg, O Spadaro, YH Youm, ... Cell metabolism 30 (6), 1024-1039. e6, 2019 | 180 | 2019 |
| A biomechanical investigation of wrist kinematics JG Andrews, Y Youm Journal of Biomechanics 12 (1), 83-93, 1979 | 179 | 1979 |
| The Nlrp3 inflammasome promotes age-related thymic demise and immunosenescence YH Youm, TD Kanneganti, B Vandanmagsar, X Zhu, A Ravussin, ... Cell reports 1 (1), 56-68, 2012 | 166 | 2012 |
| Prolongevity hormone FGF21 protects against immune senescence by delaying age-related thymic involution YH Youm, TL Horvath, DJ Mangelsdorf, SA Kliewer, VD Dixit Proceedings of the National Academy of Sciences 113 (4), 1026-1031, 2016 | 120 | 2016 |
| Deficient ghrelin receptor-mediated signaling compromises thymic stromal cell microenvironment by accelerating thymic adiposity YH Youm, H Yang, Y Sun, RG Smith, NR Manley, B Vandanmagsar, ... Journal of Biological Chemistry 284 (11), 7068-7077, 2009 | 114 | 2009 |
| Growth hormone receptor deficiency protects against age-related NLRP3 inflammasome activation and immune senescence O Spadaro, EL Goldberg, CD Camell, YH Youm, JJ Kopchick, KY Nguyen, ... Cell reports 14 (7), 1571-1580, 2016 | 96 | 2016 |
| IL-33 causes thermogenic failure in aging by expanding dysfunctional adipose ILC2 EL Goldberg, I Shchukina, YH Youm, S Ryu, T Tsusaka, KC Young, ... Cell metabolism 33 (11), 2277-2287. e5, 2021 | 69 | 2021 |
Vishwa Deep DixitProfessor, Yale UniversityVerified email at yale.edu
