| Presynaptic control of striatal glutamatergic neurotransmission by adenosine A1–A2A receptor heteromers F Ciruela, V Casadó, RJ Rodrigues, R Luján, J Burgueno, M Canals, ... Journal of Neuroscience 26 (7), 2080-2087, 2006 | 731 | 2006 |
| Coaggregation, cointernalization, and codesensitization of adenosine A2A receptors and dopamine D2Receptors J Hillion, M Canals, M Torvinen, V Casadó, R Scott, A Terasmaa, ... Journal of Biological Chemistry 277 (20), 18091-18097, 2002 | 665 | 2002 |
| Adenosine A2A-dopamine D2 receptor-receptor heteromerization: qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer M Canals, D Marcellino, F Fanelli, F Ciruela, P De Benedetti, ... Journal of Biological Chemistry 278 (47), 46741-46749, 2003 | 571 | 2003 |
| Structural basis for modulation of a G-protein-coupled receptor by allosteric drugs RO Dror, HF Green, C Valant, DW Borhani, JR Valcourt, AC Pan, ... Nature 503 (7475), 295-299, 2013 | 460 | 2013 |
| The role of kinetic context in apparent biased agonism at GPCRs C Klein Herenbrink, DA Sykes, P Donthamsetti, M Canals, T Coudrat, ... Nature communications 7 (1), 10842, 2016 | 354 | 2016 |
| Pharmacological modulation of chemokine receptor function DJ Scholten, M Canals, D Maussang, L Roumen, MJ Smit, M Wijtmans, ... British journal of pharmacology 165 (6), 1617-1643, 2012 | 316 | 2012 |
| Receptor heteromerization in adenosine A2A receptor signaling: Relevance for striatal function and Parkinson’s disease K Fuxe, LF Agnati, K Jacobsen, J Hillion, M Canals, M Torvinen, ... Neurology 61 (11_suppl_6), S19-S23, 2003 | 314 | 2003 |
| Adenosine A2A and dopamine D2 heteromeric receptor complexes and their function K Fuxe, S Ferré, M Canals, M Torvinen, A Terasmaa, D Marcellino, ... Journal of molecular neuroscience 26, 209-220, 2005 | 310 | 2005 |
| Low intrinsic efficacy for G protein activation can explain the improved side effect profiles of new opioid agonists A Gillis, AB Gondin, A Kliewer, J Sanchez, HD Lim, C Alamein, ... Science signaling 13 (625), eaaz3140, 2020 | 294 | 2020 |
| Orexin-1 receptor-cannabinoid CB1 receptor heterodimerization results in both ligand-dependent and-independent coordinated alterations of receptor localization and function J Ellis, JD Pediani, M Canals, S Milasta, G Milligan Journal of Biological Chemistry 281 (50), 38812-38824, 2006 | 284 | 2006 |
| Combining mass spectrometry and pull-down techniques for the study of receptor heteromerization. Direct epitope− epitope electrostatic interactions between adenosine A2A and … F Ciruela, J Burgueño, V Casadó, M Canals, D Marcellino, SR Goldberg, ... Analytical Chemistry 76 (18), 5354-5363, 2004 | 244 | 2004 |
| Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief DD Jensen, TM Lieu, ML Halls, NA Veldhuis, WL Imlach, QN Mai, ... Science Translational Medicine 9 (392), eaal3447, 2017 | 221 | 2017 |
| Homodimerization of adenosine A2A receptors: qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer M Canals, J Burgueño, D Marcellino, N Cabello, EI Canela, J Mallol, ... Journal of neurochemistry 88 (3), 726-734, 2004 | 219 | 2004 |
| Cannabinoid receptor type 1 protects against age-related osteoporosis by regulating osteoblast and adipocyte differentiation in marrow stromal cells AI Idris, A Sophocleous, E Landao-Bassonga, M Canals, G Milligan, ... Cell Metabolism 10 (2), 139-147, 2009 | 200 | 2009 |
| The α1b-adrenoceptor exists as a higher-order oligomer: effective oligomerization is required for receptor maturation, surface delivery, and function JF Lopez-Gimenez, M Canals, JD Pediani, G Milligan Molecular pharmacology 71 (4), 1015-1029, 2007 | 199 | 2007 |
| Adenosine A2A-dopamine D2 receptor–receptor heteromers. Targets for neuro-psychiatric disorders S Ferré, F Ciruela, M Canals, D Marcellino, J Burgueno, V Casadó, ... Parkinsonism & related disorders 10 (5), 265-271, 2004 | 190 | 2004 |
| Endosomal signaling of the receptor for calcitonin gene-related peptide mediates pain transmission RE Yarwood, WL Imlach, TM Lieu, NA Veldhuis, DD Jensen, ... Proceedings of the National Academy of Sciences 114 (46), 12309-12314, 2017 | 169 | 2017 |
| Protease-activated receptor-2 in endosomes signals persistent pain of irritable bowel syndrome NN Jimenez-Vargas, LA Pattison, P Zhao, TM Lieu, R Latorre, DD Jensen, ... Proceedings of the National Academy of Sciences 115 (31), E7438-E7447, 2018 | 167 | 2018 |
| Adenosine A2A receptor and dopamine D3 receptor interactions: evidence of functional A2A/D3 heteromeric complexes M Torvinen, D Marcellino, M Canals, LF Agnati, C Lluis, R Franco, K Fuxe Molecular pharmacology 67 (2), 400-407, 2005 | 160 | 2005 |
| Working memory deficits in transgenic rats overexpressing human adenosine A2A receptors in the brain L Giménez-Llort, SN Schiffmann, T Shmidt, L Canela, L Camón, ... Neurobiology of learning and memory 87 (1), 42-56, 2007 | 144 | 2007 |
