| Predictive markers guide differentiation to improve graft outcome in clinical translation of hESC-based therapy for Parkinson’s disease A Kirkeby, S Nolbrant, K Tiklova, A Heuer, N Kee, T Cardoso, ... Cell stem cell 20 (1), 135-148, 2017 | 301 | 2017 |
| Maladaptive plasticity of serotonin axon terminals in levodopa‐induced dyskinesia D Rylander, M Parent, SS O'Sullivan, S Dovero, AJ Lees, E Bezard, ... Annals of neurology 68 (5), 619-628, 2010 | 296 | 2010 |
| In vivo reprogramming of striatal NG2 glia into functional neurons that integrate into local host circuitry O Torper, DR Ottosson, M Pereira, S Lau, T Cardoso, S Grealish, ... Cell reports 12 (3), 474-481, 2015 | 216 | 2015 |
| Pharmacological modulation of glutamate transmission in a rat model of L-DOPA-induced dyskinesia: effects on motor behavior and striatal nuclear signaling D Rylander, A Recchia, F Mela, A Dekundy, W Danysz, MA Cenci Journal of Pharmacology and Experimental Therapeutics 330 (1), 227-235, 2009 | 213 | 2009 |
| A mGluR5 antagonist under clinical development improves L-DOPA-induced dyskinesia in parkinsonian rats and monkeys D Rylander, H Iderberg, Q Li, A Dekundy, J Zhang, H Li, R Baishen, ... Neurobiology of disease 39 (3), 352-361, 2010 | 181 | 2010 |
| The “motor complication syndrome” in rats with 6-OHDA lesions treated chronically with L-DOPA: relation to dose and route of administration HS Lindgren, D Rylander, KE Ohlin, M Lundblad, MA Cenci Behavioural brain research 177 (1), 150-159, 2007 | 139 | 2007 |
| Direct reprogramming of resident NG2 glia into neurons with properties of fast-spiking parvalbumin-containing interneurons M Pereira, M Birtele, S Shrigley, JA Benitez, E Hedlund, M Parmar, ... Stem cell reports 9 (3), 742-751, 2017 | 118 | 2017 |
| REST suppression mediates neural conversion of adult human fibroblasts via microRNA‐dependent and‐independent pathways J Drouin‐Ouellet, S Lau, PL Brattås, D Rylander Ottosson, K Pircs, ... EMBO molecular medicine 9 (8), 1117-1131, 2017 | 115 | 2017 |
| Antagonizing L-type Ca2+ channel reduces development of abnormal involuntary movement in the rat model of L-3, 4-dihydroxyphenylalanine-induced dyskinesia S Schuster, E Doudnikoff, D Rylander, A Berthet, I Aubert, C Ittrich, ... Biological psychiatry 65 (6), 518-526, 2009 | 100 | 2009 |
| Single-cell transcriptomics captures features of human midbrain development and dopamine neuron diversity in brain organoids A Fiorenzano, E Sozzi, M Birtele, J Kajtez, J Giacomoni, F Nilsson, ... Nature communications 12 (1), 7302, 2021 | 93 | 2021 |
| Huntingtin aggregation impairs autophagy, leading to argonaute-2 accumulation and global MicroRNA dysregulation K Pircs, R Petri, S Madsen, PL Brattås, R Vuono, DR Ottosson, I St-Amour, ... Cell reports 24 (6), 1397-1406, 2018 | 90 | 2018 |
| Plastic effects of L-DOPA treatment in the basal ganglia and their relevance to the development of dyskinesia MA Cenci, KE Ohlin, D Rylander Parkinsonism & related disorders 15, S59-S63, 2009 | 69 | 2009 |
| Highly efficient generation of induced neurons from human fibroblasts that survive transplantation into the adult rat brain M Pereira, U Pfisterer, D Rylander, O Torper, S Lau, M Lundblad, ... Scientific reports 4 (1), 6330, 2014 | 66 | 2014 |
| Modulating mGluR5 and 5-HT1A/1B receptors to treat l-DOPA-induced dyskinesia: effects of combined treatment and possible mechanisms of action H Iderberg, D Rylander, Z Bimpisidis, MA Cenci Experimental neurology 250, 116-124, 2013 | 54 | 2013 |
| Embedded 3D printing in self‐healing annealable composites for precise patterning of functionally mature human neural constructs J Kajtez, MF Wesseler, M Birtele, FR Khorasgani, D Rylander Ottosson, ... Advanced Science 9 (25), 2201392, 2022 | 52 | 2022 |
| Chemogenetic modulation of cholinergic interneurons reveals their regulating role on the direct and indirect output pathways from the striatum P Aldrin-Kirk, A Heuer, DR Ottosson, M Davidsson, B Mattsson, ... Neurobiology of disease 109, 148-162, 2018 | 49 | 2018 |
| Putaminal upregulation of FosB/ΔFosB-like immunoreactivity in Parkinson's disease patients with dyskinesia HS Lindgren, D Rylander, H Iderberg, M Andersson, SS O'Sullivan, ... Journal of Parkinson's disease 1 (4), 347-357, 2011 | 45 | 2011 |
| Constitutively active SMAD2/3 are broad-scope potentiators of transcription-factor-mediated cellular reprogramming T Ruetz, U Pfisterer, B Di Stefano, J Ashmore, M Beniazza, TV Tian, ... Cell Stem Cell 21 (6), 791-805. e9, 2017 | 43 | 2017 |
| Direct neural conversion from human fibroblasts using self-regulating and nonintegrating viral vectors S Lau, DR Ottosson, J Jakobsson, M Parmar Cell Reports 9 (5), 1673-1680, 2014 | 42 | 2014 |
| Region-specific restoration of striatal synaptic plasticity by dopamine grafts in experimental parkinsonism D Rylander, V Bagetta, V Pendolino, E Zianni, S Grealish, F Gardoni, ... Proceedings of the National Academy of Sciences 110 (46), E4375-E4384, 2013 | 31 | 2013 |